8D3R
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8D33
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7JZS
| Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with CoA | 分子名称: | Aminoglycoside 2'-N-acetyltransferase, COENZYME A, DI(HYDROXYETHYL)ETHER, ... | 著者 | Park, J, Bassenden, A.V, Berghuis, A.M. | 登録日 | 2020-09-02 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep, 11, 2021
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7SVU
| TnsBctd-TnsC-TniQ complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex Nature, 613, 2023
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5BYE
| Crystal structure of human ribokinase in P212121 spacegroup | 分子名称: | CHLORIDE ION, Ribokinase, SODIUM ION | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-10 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of human ribokinase in P212121 spacegroup To Be Published
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5BYC
| Crystal structure of human ribokinase in C2 spacegroup | 分子名称: | Ribokinase, SODIUM ION | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-10 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of unliganded human ribokinase in C2 spacegroup To Be Published
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5C41
| Crystal structure of human ribokinase in complex with AMPPCP in P21 spacegroup and with 4 protomers | 分子名称: | PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ribokinase, ... | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-17 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of human ribokinase in complex with AMPPCP in P21 spacegroup and with 4 protomers To Be Published
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5C3Z
| Crystal structure of human ribokinase in complex with AMPPCP in C2 spacegroup | 分子名称: | CHLORIDE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ribokinase, ... | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-17 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human ribokinase in complex with AMPPCP in C2 spacegroup To Be Published
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5BYD
| Crystal structure of human ribokinase in P21 spacegroup | 分子名称: | POTASSIUM ION, Ribokinase, SODIUM ION | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-10 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of human ribokinase in P21 spacegroup To Be Published
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5BYF
| Crystal structure of human ribokinase in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Ribokinase, ... | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-10 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of human ribokinase in complex with AMP To Be Published
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5C40
| Crystal structure of human ribokinase in complex with AMPPCP in P21 spacegroup | 分子名称: | PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ribokinase, ... | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-17 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of human ribokinase in complex with AMPPCP in P21 spacegroup To Be Published
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5C3Y
| Structure of human ribokinase crystallized with AMPPNP | 分子名称: | AMP PHOSPHORAMIDATE, Ribokinase, SODIUM ION | 著者 | Park, J, Chakrabarti, J, Singh, B, Gupta, R.S, Junop, M.S. | 登録日 | 2015-06-17 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human ribokinase crystallized with AMPPNP To Be Published
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4GO6
| Crystal structure of HCF-1 self-association sequence 1 | 分子名称: | HCF C-terminal chain 1, HCF N-terminal chain 1, SULFATE ION | 著者 | Park, J, Lammers, F, Herr, W, Song, J. | 登録日 | 2012-08-18 | 公開日 | 2012-10-17 | 最終更新日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | HCF-1 self-association via an interdigitated Fn3 structure facilitates transcriptional regulatory complex formation Proc.Natl.Acad.Sci.USA, 109, 2012
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6LE5
| Crystal structure of the mitochondrial calcium uptake 1 and 2 heterodimer (MICU1-MICU2 heterodimer) in an apo state | 分子名称: | Calcium uptake protein 1, mitochondrial, Calcium uptake protein 2 | 著者 | Park, J, Lee, Y, Park, T, Kang, J.Y, Jin, M, Yang, J, Eom, S.H. | 登録日 | 2019-11-24 | 公開日 | 2020-03-04 | 最終更新日 | 2020-03-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the MICU1-MICU2 heterodimer provides insights into the gatekeeping threshold shift. Iucrj, 7, 2020
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4DEM
| Crystal structure of human FPPS in complex with YS_04_70 | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, [({4-[4-(propan-2-yloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid) | 著者 | Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2012-01-20 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. J.Med.Chem., 55, 2012
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6C56
| Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in its Apo form | 分子名称: | Geranylgeranyl pyrophosphate synthase, {[(2-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid) | 著者 | Park, J, Ta, V, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2018-01-15 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. J. Med. Chem., 61, 2018
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6C57
| Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in complex with bisphosphonate inhibitor FV0109 | 分子名称: | Geranylgeranyl pyrophosphate synthase, {[(2-{3-[(4-fluorobenzene-1-carbonyl)amino]phenyl}thieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid) | 著者 | Park, J, Bin, X, Vincent, F, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2018-01-15 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. J. Med. Chem., 61, 2018
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4LPG
| Crystal structure of human FPPS in complex with CL01131 | 分子名称: | ({[6-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methanediyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, PHOSPHATE ION | 著者 | Park, J, Leung, C.Y, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2013-07-16 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. J.Med.Chem., 57, 2014
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7VGM
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7SVV
| TnsBctd-TnsC complex | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | 登録日 | 2021-11-19 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SVW
| Strand-transfer complex of TnsB from ShCAST | 分子名称: | MAGNESIUM ION, STC_LE_For, STC_LE_Rev1, ... | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | 登録日 | 2021-11-19 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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4XQT
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4XQS
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4ZEV
| Crystal structure of PfHAD1 in complex with mannose-6-phosphate | 分子名称: | 6-O-phosphono-alpha-D-mannopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Park, J, Tolia, N.H. | 登録日 | 2015-04-20 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEW
| Crystal structure of PfHAD1 in complex with glucose-6-phosphate | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Park, J, Tolia, N.H. | 登録日 | 2015-04-20 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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