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PDB: 191 results

6WRP
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Crystal Structure of PI3-E12 Fab, An Antibody Against Human Parainfluenza Virus Type III
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2020-04-29
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Protective antibodies against human parainfluenza virus type 3 infection.
Mabs, 13, 2021
6XE1
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Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a potent neutralizing antibody, CV30 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV30 Fab Heavy chain, CV30 Fab Kappa chain, ...
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2020-06-11
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
Nat Commun, 11, 2020
6OL7
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BU of 6ol7 by Molmil
Crystal structure of glVRC01 scFv in complex with anti-idiotype iv8 scFv
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2019-04-15
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.419 Å)
Cite:Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
J.Exp.Med., 216, 2019
6XOC
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BU of 6xoc by Molmil
Crystal structure of glVRC01 Fab in complex with anti-idiotypic iv4 Fab
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Aljedani, S.S, Weidle, C, Pancera, M.
Deposit date:2020-07-06
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6OL5
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Structure of iglb12 Fab in complex with anti-idiotype ib3 Fab
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2019-04-15
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6XLZ
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BU of 6xlz by Molmil
Structure of NHP D11A.F2 Fab in complex with 16055 V2b peptide
Descriptor: (R,R)-2,3-BUTANEDIOL, Envelope glycoprotein gp160, NHP_D11A.F2_Fab_Heavy_chain, ...
Authors:Aljedani, S, Rodarte, J, Liban, T, Pancera, M.
Deposit date:2020-06-29
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6XSN
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BU of 6xsn by Molmil
Crystal structure of NHP VD20.5A4 Fab in complex with 16055 V1V2 1FD6 scaffold
Descriptor: 1,2-ETHANEDIOL, 16055_V1V2-1FD6, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Aljedani, S, Pancera, M.
Deposit date:2020-07-15
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
7MYT
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BU of 7myt by Molmil
Crystal Structure of HPV L1-directed B25.M05 Fab
Descriptor: B25.M05 Fab Heavy Chain, B25.M05 Fab Light Chain
Authors:Singh, S, Pancera, M.
Deposit date:2021-05-21
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of Immune Responses to HPV vaccination
To Be Published
8DG8
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BU of 8dg8 by Molmil
Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3x1 monoclonal antibody, VH region, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2022-06-23
Release date:2023-02-22
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
8DG9
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BU of 8dg9 by Molmil
Cryo-EM Structure of RSV prefusion F trimer in complex with three MxR Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAb MxR Heavy Chain, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2022-06-23
Release date:2023-02-22
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
3TCL
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BU of 3tcl by Molmil
Crystal Structure of HIV-1 Neutralizing Antibody CH04
Descriptor: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
Authors:Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D.
Deposit date:2011-08-09
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
1FSK
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BU of 1fsk by Molmil
COMPLEX FORMATION BETWEEN A FAB FRAGMENT OF A MONOCLONAL IGG ANTIBODY AND THE MAJOR ALLERGEN FROM BIRCH POLLEN BET V 1
Descriptor: ANTIBODY HEAVY CHAIN FAB, IMMUNOGLOBULIN KAPPA LIGHT CHAIN, MAJOR POLLEN ALLERGEN BET V 1-A
Authors:Mirza, O, Henriksen, A, Ipsen, H, Larsen, J, Wissenbach, M, Spangfort, M, Gajhede, M.
Deposit date:2000-09-11
Release date:2000-10-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1.
J.Immunol., 165, 2000
6C5V
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BU of 6c5v by Molmil
An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ...
Authors:Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-16
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
7RAQ
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BU of 7raq by Molmil
Crystal structure of CV3-25 Fab bound to SARS-CoV-2 spike stem helix peptide
Descriptor: CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, GLYCEROL, ...
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2021-07-02
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
Commun Biol, 5, 2022
7RDW
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BU of 7rdw by Molmil
Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2021-07-12
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.
Sci Adv, 8, 2022
3U46
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BU of 3u46 by Molmil
CH04H/CH02L P212121
Descriptor: CH02 Light chain Fab, CH04 Heavy chain Fab
Authors:Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4E
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BU of 3u4e by Molmil
Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain CAP45
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG9 Heavy Chain, PG9 Light Chain, ...
Authors:Gorman, J, McLellan, J, Pancera, M, Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.185 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U2S
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BU of 3u2s by Molmil
Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:McLellan, J.S, Pancera, M, Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
1FB5
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BU of 1fb5 by Molmil
LOW RESOLUTION STRUCTURE OF OVINE ORNITHINE TRANSCARBMOYLASE IN THE UNLIGANDED STATE
Descriptor: NORVALINE, ORNITHINE TRANSCARBAMOYLASE
Authors:Zanotti, G, Battistutta, R, Panzalorto, M, Francescato, P, Bruno, G, De Gregorio, A.
Deposit date:2000-07-14
Release date:2003-08-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Functional and structural characterization of ovine ornithine transcarbamoylase.
Org.Biomol.Chem., 1, 2003
2KM2
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BU of 2km2 by Molmil
Galectin-1 dimer
Descriptor: Galectin-1
Authors:Nesmelova, I.V, Ermakova, E, Daragan, V.A, Pang, M, Baum, L.G, Mayo, K.H.
Deposit date:2009-07-16
Release date:2010-04-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Lactose binding to galectin-1 modulates structural dynamics, increases conformational entropy, and occurs with apparent negative cooperativity.
J.Mol.Biol., 397, 2010
8EN4
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BU of 8en4 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 53
Descriptor: 1,2-ETHANEDIOL, Nanobody 53, VP1
Authors:Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN5
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BU of 8en5 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 56
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GII.4 P domain, ...
Authors:Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EMZ
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BU of 8emz by Molmil
Structure of GII.17 norovirus in complex with Nanobody 2
Descriptor: 1,2-ETHANEDIOL, GII.17 P domain, Nanobody 2
Authors:Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN0
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Structure of GII.17 norovirus in complex with Nanobody 7
Descriptor: Capsid protein VP1, Nanobody 7
Authors:Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN1
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BU of 8en1 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 30
Descriptor: GII.4 P domain, Nanobody 30
Authors:Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023

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