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PDB: 36 件
7LN4
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BU of 7ln4 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LMY
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BU of 7lmy by Molmil
Cryo-EM structure of human p97 in complex with NMS-873 in the presence of ATP, Npl4/Ufd1, and Ub6
分子名称: 3-[3-cyclopentylsulfanyl-5-[[3-methyl-4-(4-methylsulfonylphenyl)phenoxy]methyl]-1,2,4-triazol-4-yl]pyridine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN5
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BU of 7ln5 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 1, Close State)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN3
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BU of 7ln3 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN0
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BU of 7ln0 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN1
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BU of 7ln1 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN2
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BU of 7ln2 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LMZ
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BU of 7lmz by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN6
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BU of 7ln6 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7MEX
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BU of 7mex by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and N-degron
分子名称: E3 ubiquitin-protein ligase UBR1, N-degron, Ubiquitin, ...
著者Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
登録日2021-04-08
公開日2021-11-24
最終更新日2021-12-22
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
7MEY
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BU of 7mey by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron
分子名称: 2-(ethylamino)ethane-1-thiol, E3 ubiquitin-protein ligase UBR1, Monoubiquitinated N-degron, ...
著者Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
登録日2021-04-08
公開日2021-11-24
最終更新日2021-12-22
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
5JBY
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BU of 5jby by Molmil
Lys27-linked triubiquitin
分子名称: D-ubiquitin, ubiquitin
著者Pan, M, Gao, S, Zheng, Y.
登録日2016-04-14
公開日2016-07-20
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (1.987 Å)
主引用文献Structure of Lys27-linked triubiquitin
To Be Published
5JBV
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BU of 5jbv by Molmil
Lys27-linked triubiquitin
分子名称: D-ubiquitin, NITRATE ION, Ubiquitin
著者Pan, M, Gao, S, Zheng, Y.
登録日2016-04-13
公開日2016-05-18
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Structure of Lys27-linked triubiquitin
To Be Published
5J8P
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BU of 5j8p by Molmil
Lys27-linked diubiquitin
分子名称: D-ubiquitin, MAGNESIUM ION, ubiquitin
著者Pan, M, Gao, S, Zheng, Y.
登録日2016-04-08
公開日2016-05-18
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (1.554 Å)
主引用文献Structure of Lys27-linked diubiquitin
To Be Published
7JY5
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BU of 7jy5 by Molmil
Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97)
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2020-08-28
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative.
Nat Commun, 12, 2021
6ISU
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BU of 6isu by Molmil
Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L3
著者Ding, S, Pan, M, Zheng, Q, Ren, Y, Hong, D.
登録日2018-11-19
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.866 Å)
主引用文献Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains.
Angew. Chem. Int. Ed. Engl., 58, 2019
8IEJ
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BU of 8iej by Molmil
RNF20-RNF40/hRad6A-Ub/nucleosome complex
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Ai, H, Deng, Z, Sun, M, Du, Y, Pan, M, Liu, L.
登録日2023-02-15
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
7MGQ
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BU of 7mgq by Molmil
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans
分子名称: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, MAGNESIUM ION
著者Wizrah, M.S, Chua, S.M.H, Luo, Z, Manik, M.K, Pan, M, Whyte, J.M, Robertson, A.B, Kappler, U, Kobe, B, Fraser, J.A.
登録日2021-04-13
公開日2022-04-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
J.Biol.Chem., 298, 2022
8IEG
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BU of 8ieg by Molmil
Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase BRE1, Histone H2A type 1-B/E, ...
著者Ai, H, Deng, Z, Pan, M, Liu, L.
登録日2023-02-15
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
3LX2
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BU of 3lx2 by Molmil
Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582
分子名称: DNA polymerase sliding clamp 2, SULFATE ION
著者Ladner, J.E, Kelman, Z, Pan, M.
登録日2010-02-24
公開日2011-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3LX1
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BU of 3lx1 by Molmil
Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535
分子名称: DNA polymerase sliding clamp 1, SULFATE ION
著者Ladner, J.E, Kelman, Z, Pan, M.
登録日2010-02-24
公開日2011-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
5GO7
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BU of 5go7 by Molmil
Linear tri-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOC
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BU of 5goc by Molmil
Lys11-linked diubiquitin
分子名称: D-ubiquitin, SODIUM ION, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.733 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOI
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BU of 5goi by Molmil
Lys48-linked di-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y, Liu, L.
登録日2016-07-27
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5GOG
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BU of 5gog by Molmil
Lys29-linked di-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-27
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.977 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016

 

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