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PDB: 216 件
2QOF
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Human EphA3 kinase and juxtamembrane region, Y596F mutant
分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QO2
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Human EphA3 kinase and juxtamembrane region, dephosphorylated, apo structure
分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-19
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2R2P
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BU of 2r2p by Molmil
Kinase domain of human ephrin type-A receptor 5 (EphA5)
分子名称: CHLORIDE ION, Ephrin type-A receptor 5, SULFATE ION
著者Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-08-27
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Kinase Domain of Human Ephrin Type-A Receptor 5 (EphA5).
To be Published
2G7R
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BU of 2g7r by Molmil
X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1
分子名称: Mucosa-associated lymphoid tissue lymphoma translocation protein 1
著者Walker, J.R, Wybenga-Groot, L, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-02-28
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1
To be Published
2QO7
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BU of 2qo7 by Molmil
Human EphA3 kinase and juxtamembrane region, dephosphorylated, AMP-PNP bound
分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor, GLYCEROL, ...
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.605 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOI
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BU of 2qoi by Molmil
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F double mutant
分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2GSF
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BU of 2gsf by Molmil
The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region
分子名称: Ephrin type-A receptor 3
著者Walker, J.R, Davis, T, Dong, A, Newman, E.M, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-04-26
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure Of The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region
To be Published
3DL2
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BU of 3dl2 by Molmil
Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
分子名称: PHOSPHATE ION, SODIUM ION, Ubiquitin-conjugating enzyme E2 variant 3
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Bountra, C, Wolkstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-06-26
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Investigation Into the L-Lactate Dehydrogenase Domain of Human Ubiquitin-Conjugating Enzyme E2-Like Isoform A.
To be Published
3ECI
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BU of 3eci by Molmil
Microtubule-associated protein 1 light chain 3 alpha isoform A (MAP1ALC3)
分子名称: Microtubule-associated protein 1 light chain 3 alpha
著者Walker, J.R, Davis, T.L, Mujib, S, Butler-Cole, C, Tempel, W, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S.
登録日2008-08-30
公開日2008-10-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Human Autophagy-Related Protein LC3 A
To be Published
2H6D
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BU of 2h6d by Molmil
Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain)
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-2
著者Littler, D.R, Walker, J.R, Wybenga-Groot, L, Newman, E.M, Butler-Cole, C, Mackenzie, F, Finerty, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-05-31
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Acta Crystallogr.,Sect.F, 66, 2010
2QFE
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BU of 2qfe by Molmil
Distal C2-Like Domain of Human Calpain-7
分子名称: BROMIDE ION, Calpain-7
著者Walker, J.R, Cuerrier, D, Ravulapalli, R, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S.
登録日2007-06-27
公開日2007-07-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of the C2 Domain of Human Calpain-7
To be Published
3CEG
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BU of 3ceg by Molmil
Crystal structure of the UBC domain of baculoviral IAP repeat-containing protein 6
分子名称: Baculoviral IAP repeat-containing protein 6
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-02-29
公開日2008-04-01
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.008 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2QOC
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BU of 2qoc by Molmil
Human EphA3 kinase domain, phosphorylated, AMP-PNP bound structure
分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor, MAGNESIUM ION, ...
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOK
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BU of 2qok by Molmil
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:S768A triple mutant
分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2FK9
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BU of 2fk9 by Molmil
Human protein kinase C, eta
分子名称: protein kinase C, eta type
著者Walker, J.R, Littler, D.R, Finerty Jr, P.J, MacKenzie, F, Newman, E.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-01-04
公開日2006-01-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of human protein kinase C eta (PKCeta) C2 domain and identification of phosphorylation sites.
Biochem.Biophys.Res.Commun., 349, 2006
3EPZ
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BU of 3epz by Molmil
Structure of the replication foci-targeting sequence of human DNA cytosine methyltransferase DNMT1
分子名称: DNA (cytosine-5)-methyltransferase 1, GLYCEROL, SODIUM ION, ...
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-09-30
公開日2008-11-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.
J.Biol.Chem., 286, 2011
3FL2
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BU of 3fl2 by Molmil
Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-12-18
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of the Ring Domain of the E3 Ubiquitin-Protein Ligase Uhrf1
To be Published
3BPR
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BU of 3bpr by Molmil
Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52
分子名称: 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase MER, ...
著者Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-12-19
公開日2008-01-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the inhibited states of the Mer receptor tyrosine kinase.
J.Struct.Biol., 165, 2009
2QOO
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BU of 2qoo by Molmil
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742F triple mutant
分子名称: Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QON
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BU of 2qon by Molmil
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742A triple mutant
分子名称: Ephrin receptor, GLYCEROL
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOD
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BU of 2qod by Molmil
Human EphA3 kinase and juxtamembrane region, Y602F mutant
分子名称: Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2LFE
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BU of 2lfe by Molmil
Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A
分子名称: E3 ubiquitin-protein ligase HECW2
著者Lemak, A, Yee, A, Houliston, S, Garcia, M, Chitayat, S, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2011-06-29
公開日2011-07-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure of N-terminal domain of E3 ligase HECW2
To be Published
2QO9
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BU of 2qo9 by Molmil
Human EphA3 kinase and juxtamembrane region, phosphorylated, AMP-PNP bound
分子名称: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QOL
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BU of 2qol by Molmil
Human EphA3 kinase and juxtamembrane region, Y596:Y602:S768G triple mutant
分子名称: Ephrin receptor
著者Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-20
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2REI
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BU of 2rei by Molmil
Kinase domain of human ephrin type-A receptor 7 (Epha7)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Ephrin type-A receptor 7
著者Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-09-26
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Kinase Domain of Human Ephrin Type-A Receptor 7 (Epha7).
To be Published

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