1P1V
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![BU of 1p1v by Molmil](/molmil-images/mine/1p1v) | Crystal Structure of FALS-associated human Copper-Zinc Superoxide Dismutase (CuZnSOD) Mutant D125H to 1.4A | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Elam, J.S, Malek, K, Rodriguez, J.A, Doucette, P.A, Taylor, A.B, Hayward, L.J, Cabelli, D.E, Valentine, J.S, Hart, P.J. | Deposit date: | 2003-04-14 | Release date: | 2003-08-26 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | An Alternative Mechanism of Bicarbonate-mediated Peroxidation by Copper-Zinc Superoxide Dismutase: RATES ENHANCED VIA PROPOSED ENZYME-ASSOCIATED PEROXYCARBONATE INTERMEDIATE J.Biol.Chem., 278, 2003
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4IQG
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![BU of 4iqg by Molmil](/molmil-images/mine/4iqg) | Crystal structure of BPRO0239 oxidoreductase from Polaromonas sp. JS666 in NADP bound form | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, GLYCEROL, ... | Authors: | Niedzialkowska, E, Majorek, K.A, Porebski, P.J, Al Obaidi, N, Hammonds, J, Hillerich, B, Seidel, R, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-01-11 | Release date: | 2013-01-30 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of oxidoreductase from Polaromonas sp. in NADP bound form To be Published
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4ILB
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![BU of 4ilb by Molmil](/molmil-images/mine/4ilb) | The pentameric ligand-gated ion channel GLIC A237F in complex with Rubidium | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Sauguet, L, Corringer, P.J, Delarue, M. | Deposit date: | 2012-12-29 | Release date: | 2013-02-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4H7W
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![BU of 4h7w by Molmil](/molmil-images/mine/4h7w) | Crystal Structure of Human C16orf57 | Descriptor: | CHLORIDE ION, GLYCEROL, UPF0406 protein C16orf57 | Authors: | Hilcenko, C, Simpson, P.J, Warren, A.J. | Deposit date: | 2012-09-21 | Release date: | 2013-02-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Aberrant 3' oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia. Blood, 121, 2013
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4PHN
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![BU of 4phn by Molmil](/molmil-images/mine/4phn) | The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids | Descriptor: | CALCIUM ION, Calpain small subunit 1 | Authors: | Allemann, R.K, Rizkallah, P.J, Adams, S.E, Miller, D.J, Hallett, M.B. | Deposit date: | 2014-05-06 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
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1N4R
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![BU of 1n4r by Molmil](/molmil-images/mine/1n4r) | Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ... | Authors: | Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S. | Deposit date: | 2002-11-01 | Release date: | 2003-11-18 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of mammalian protein geranylgeranyltransferase type-I EMBO J., 22, 2003
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1N4P
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![BU of 1n4p by Molmil](/molmil-images/mine/1n4p) | Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate | Descriptor: | CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ... | Authors: | Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S. | Deposit date: | 2002-11-01 | Release date: | 2003-11-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of mammalian protein geranylgeranyltransferase type-I EMBO J., 22, 2003
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4PHJ
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![BU of 4phj by Molmil](/molmil-images/mine/4phj) | The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids: Human unliganded protein | Descriptor: | CALCIUM ION, Calpain small subunit 1 | Authors: | Adams, S.E, Rizkallah, P.J, Allemann, R.K, Miller, D.J, Hallett, M.B, Robinson, E. | Deposit date: | 2014-05-06 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
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1PWB
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![BU of 1pwb by Molmil](/molmil-images/mine/1pwb) | High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D with maltose | Descriptor: | CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-glucopyranose, ... | Authors: | Shrive, A.K, Tharia, H.A, Strong, P, Kishore, U, Burns, I, Rizkallah, P.J, Reid, K.B, Greenhough, T.J. | Deposit date: | 2003-07-01 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D J.Mol.Biol., 331, 2003
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1Q52
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![BU of 1q52 by Molmil](/molmil-images/mine/1q52) | Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis | Descriptor: | menB | Authors: | Truglio, J.J, Theis, K, Feng, Y, Gajda, R, Machutta, C, Tonge, P.J, Kisker, C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-08-05 | Release date: | 2004-01-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J.Biol.Chem., 278, 2003
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1PW9
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![BU of 1pw9 by Molmil](/molmil-images/mine/1pw9) | High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D | Descriptor: | CALCIUM ION, Pulmonary surfactant-associated protein D | Authors: | Shrive, A.K, Tharia, H.A, Strong, P, Kishore, U, Burns, I, Rizkallah, P.J, Reid, K.B, Greenhough, T.J. | Deposit date: | 2003-07-01 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D J.Mol.Biol., 331, 2003
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4HFI
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![BU of 4hfi by Molmil](/molmil-images/mine/4hfi) | The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Sauguet, L, Corringer, P.J, Delarue, M. | Deposit date: | 2012-10-05 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4HFE
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![BU of 4hfe by Molmil](/molmil-images/mine/4hfe) | The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to ethanol | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. | Deposit date: | 2012-10-05 | Release date: | 2013-04-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4, 2013
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1Q4G
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![BU of 1q4g by Molmil](/molmil-images/mine/1q4g) | 2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid | Descriptor: | 2-(1,1'-BIPHENYL-4-YL)PROPANOIC ACID, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Gupta, K, Selinksy, B.S, Kaub, C.J, Katz, A.K, Loll, P.J. | Deposit date: | 2003-08-03 | Release date: | 2004-01-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0A Resolution Crystal Structure of Prostaglandin H(2) Synthase-1: Structural Insights into an Unusual Peroxidase J.Mol.Biol., 335, 2004
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4QQ6
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![BU of 4qq6 by Molmil](/molmil-images/mine/4qq6) | Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule | Descriptor: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION | Authors: | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2014-06-26 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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4QQD
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![BU of 4qqd by Molmil](/molmil-images/mine/4qqd) | Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule | Descriptor: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, E3 ubiquitin-protein ligase UHRF1, UNKNOWN ATOM OR ION | Authors: | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2014-06-27 | Release date: | 2014-08-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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1PL7
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![BU of 1pl7 by Molmil](/molmil-images/mine/1pl7) | Human Sorbitol Dehydrogenase (apo) | Descriptor: | Sorbitol dehydrogenase, ZINC ION | Authors: | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | Deposit date: | 2003-06-07 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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4P48
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![BU of 4p48 by Molmil](/molmil-images/mine/4p48) | The structure of a chicken anti-cardiac Troponin I scFv | Descriptor: | Antibody scFv 180 | Authors: | Conroy, P.J, Law, R.H.P, Gillgunn, S, Hearty, S, Caradoc-Davies, T.T, Llyod, G, O'Kennedy, R.J, Whisstock, J.C. | Deposit date: | 2014-03-12 | Release date: | 2014-04-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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4P49
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![BU of 4p49 by Molmil](/molmil-images/mine/4p49) | The structure of a chicken anti-prostate specific antigen scFv | Descriptor: | ACETATE ION, Antibody scFv B8, SULFATE ION | Authors: | Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C. | Deposit date: | 2014-03-12 | Release date: | 2014-04-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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4P6I
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![BU of 4p6i by Molmil](/molmil-images/mine/4p6i) | Crystal structure of the Cas1-Cas2 complex from Escherichia coli | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 | Authors: | Nunez, J.K, Kranzusch, P.J, Noeske, J, Doudna, J.A. | Deposit date: | 2014-03-24 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity. Nat.Struct.Mol.Biol., 21, 2014
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1PL6
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![BU of 1pl6 by Molmil](/molmil-images/mine/1pl6) | Human SDH/NADH/inhibitor complex | Descriptor: | 4-[2-(HYDROXYMETHYL)PYRIMIDIN-4-YL]-N,N-DIMETHYLPIPERAZINE-1-SULFONAMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Sorbitol dehydrogenase, ... | Authors: | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | Deposit date: | 2003-06-07 | Release date: | 2004-02-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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4GKZ
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![BU of 4gkz by Molmil](/molmil-images/mine/4gkz) | HA1.7, a MHC class II restricted TCR specific for haemagglutinin | Descriptor: | 1,2-ETHANEDIOL, Alpha chain of Class II TCR, Beta Chain of Class II TCR, ... | Authors: | Holland, C.J, Rizkallah, P.J, Cole, D.K, Sewell, A.K, Godkin, A.J. | Deposit date: | 2012-08-13 | Release date: | 2012-11-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers. Sci Rep, 2, 2012
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1PL8
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![BU of 1pl8 by Molmil](/molmil-images/mine/1pl8) | human SDH/NAD+ complex | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, human sorbitol dehydrogenase | Authors: | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | Deposit date: | 2003-06-07 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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1Q2J
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![BU of 1q2j by Molmil](/molmil-images/mine/1q2j) | Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA | Descriptor: | Mu-conotoxin SmIIIA | Authors: | Keizer, D.W, West, P.J, Lee, E.F, Olivera, B.M, Bulaj, G, Yoshikami, D, Norton, R.S. | Deposit date: | 2003-07-24 | Release date: | 2004-02-24 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA. J.Biol.Chem., 278, 2003
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1Q51
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![BU of 1q51 by Molmil](/molmil-images/mine/1q51) | Crystal Structure of Mycobacterium tuberculosis MenB in Complex with Acetoacetyl-Coenzyme A, a Key Enzyme in Vitamin K2 Biosynthesis | Descriptor: | ACETOACETYL-COENZYME A, menB | Authors: | Truglio, J.J, Theis, K, Feng, Y, Gajda, R, Machutta, C, Tonge, P.J, Kisker, C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-08-05 | Release date: | 2004-01-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J.Biol.Chem., 278, 2003
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