4PHN

The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids

Summary for 4PHN

• Entry DOI: 10.2210/pdb4phn/pdb
• Related: 4PHJ
• Descriptor: Calpain small subunit 1, CALCIUM ION (3 entities in total)
• Functional Keywords: calcium binding, protease, hydrolase
• Biological source: Sus scrofa (Pig)
• Cellular location: Cytoplasm : P04574
• Total number of polymer chains: 2
• Total formula weight: 40087.58

Authors

Allemann, R.K.,Rizkallah, P.J.,Adams, S.E.,Miller, D.J.,Hallett, M.B. (deposition date: 2014-05-06, release date: 2014-08-13, Last modification date: 2023-12-20)

• Primary citation: Adams, S.E.,Rizkallah, P.J.,Miller, D.J.,Robinson, E.J.,Hallett, M.B.,Allemann, R.K.; The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids.; J.Struct.Biol., 187:236-241, 2014; PubMed: 25086406; DOI: 10.1016/j.jsb.2014.07.004

Experimental method

X-RAY DIFFRACTION (1.79 Å)