4PHJ

The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids: Human unliganded protein

Summary for 4PHJ

Entry DOI	10.2210/pdb4phj/pdb
Descriptor	Calpain small subunit 1, CALCIUM ION (3 entities in total)
Functional Keywords	domain vi, pef(s), calcium binding, protease, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P04632
Total number of polymer chains	2
Total formula weight	40353.84
Authors	Adams, S.E.,Rizkallah, P.J.,Allemann, R.K.,Miller, D.J.,Hallett, M.B.,Robinson, E. (deposition date: 2014-05-06, release date: 2014-08-13, Last modification date: 2023-12-20)
Primary citation	Adams, S.E.,Rizkallah, P.J.,Miller, D.J.,Robinson, E.J.,Hallett, M.B.,Allemann, R.K. The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187:236-241, 2014 Cited by PubMed: 25086406 DOI: 10.1016/j.jsb.2014.07.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation