3VG0
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![BU of 3vg0 by Molmil](/molmil-images/mine/3vg0) | Antibody Fab fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Monoclonal antibody 9F8 Fab fragment H chain, ... | 著者 | Carpenter, B, Hemsworth, G.R, Ross, R.J, Artymiuk, P.J. | 登録日 | 2012-01-10 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody. Structure, 20, 2012
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1BWP
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![BU of 1bwp by Molmil](/molmil-images/mine/1bwp) | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | 著者 | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | 登録日 | 1998-09-27 | 公開日 | 1999-05-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase Protein Eng., 12, 1999
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2W0F
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![BU of 2w0f by Molmil](/molmil-images/mine/2w0f) | Potassium Channel KcsA-Fab Complex with Tetraoctylammonium | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | 著者 | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | 登録日 | 2008-08-14 | 公開日 | 2009-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
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1BSX
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![BU of 1bsx by Molmil](/molmil-images/mine/1bsx) | STRUCTURE AND SPECIFICITY OF NUCLEAR RECEPTOR-COACTIVATOR INTERACTIONS | 分子名称: | 3,5,3'TRIIODOTHYRONINE, PROTEIN (GRIP1), PROTEIN (THYROID HORMONE RECEPTOR BETA) | 著者 | Wagner, R.L, Darimont, B.D, Apriletti, J.W, Stallcup, M.R, Kushner, P.J, Baxter, J.D, Fletterick, R.J, Yamamoto, K.R. | 登録日 | 1998-08-31 | 公開日 | 1999-08-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev., 12, 1998
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1BWR
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![BU of 1bwr by Molmil](/molmil-images/mine/1bwr) | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | 著者 | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | 登録日 | 1998-09-27 | 公開日 | 1999-05-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase Protein Eng., 12, 1999
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2WUW
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![BU of 2wuw by Molmil](/molmil-images/mine/2wuw) | Crystallographic analysis of counter-ion effects on subtilisin enzymatic action in acetonitrile (native data) | 分子名称: | ACETONITRILE, CALCIUM ION, SODIUM ION, ... | 著者 | Cianci, M, Tomaszewki, B, Helliwell, J.R, Halling, P.J. | 登録日 | 2009-10-09 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Crystallographic Analysis of Counterion Effects on Subtilisin Enzymatic Action in Acetonitrile. J.Am.Chem.Soc., 132, 2010
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3E0G
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![BU of 3e0g by Molmil](/molmil-images/mine/3e0g) | Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ... | 著者 | Lupardus, P.J, Garcia, K.C. | 登録日 | 2008-07-31 | 公開日 | 2008-09-23 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol.Cell, 31, 2008
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2X22
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![BU of 2x22 by Molmil](/molmil-images/mine/2x22) | crystal structure of M. tuberculosis InhA inhibited by PT70 | 分子名称: | 5-HEXYL-2-(2-METHYLPHENOXY)PHENOL, DIMETHYL SULFOXIDE, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], ... | 著者 | Luckner, S.R, Liu, N, am Ende, C.W, Tonge, P.J, Kisker, C. | 登録日 | 2010-01-10 | 公開日 | 2010-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Slow, Tight Binding Inhibitor of Inha, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium Tuberculosis. J.Biol.Chem., 285, 2010
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1BVE
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![BU of 1bve by Molmil](/molmil-images/mine/1bve) | HIV-1 PROTEASE-DMP323 COMPLEX IN SOLUTION, NMR, 28 STRUCTURES | 分子名称: | HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE | 著者 | Yamazaki, T, Hinck, A.P, Wang, Y.-X, Nicholson, L.K, Torchia, D.A, Wingfield, P, Stahl, S.J, Kaufman, J.D, Chang, C, Domaille, P.J, Lam, P.Y.S. | 登録日 | 1996-01-16 | 公開日 | 1996-08-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy. Protein Sci., 5, 1996
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3GZO
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![BU of 3gzo by Molmil](/molmil-images/mine/3gzo) | HUMAN SOD1 G93A Variant | 分子名称: | COPPER (II) ION, GLYCEROL, MALONATE ION, ... | 著者 | Galaleldeen, A, Taylor, A.B, Narayana, N, Whitson, L.J, Hart, P.J. | 登録日 | 2009-04-07 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A. Arch.Biochem.Biophys., 492, 2009
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4A20
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![BU of 4a20 by Molmil](/molmil-images/mine/4a20) | Crystal structure of the Ubl domain of Mdy2 (Get5) at 1.78A | 分子名称: | SULFATE ION, UBIQUITIN-LIKE PROTEIN MDY2 | 著者 | Simon, A.C, Simpson, P.J, Murray, J.W, Isaacson, R.L. | 登録日 | 2011-09-21 | 公開日 | 2012-11-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of the Sgt2/Get5 Complex Provides Insights Into Get-Mediated Targeting of Tail-Anchored Membrane Proteins Proc.Natl.Acad.Sci.USA, 110, 2013
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1BVG
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![BU of 1bvg by Molmil](/molmil-images/mine/1bvg) | HIV-1 PROTEASE-DMP323 COMPLEX IN SOLUTION, NMR MINIMIZED AVERAGE STRUCTURE | 分子名称: | HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE | 著者 | Yamazaki, T, Hinck, A.P, Wang, Y.-X, Nicholson, L.K, Torchia, D.A, Wingfield, P, Stahl, S.J, Kaufman, J.D, Chang, C, Domaille, P.J, Lam, P.Y.S. | 登録日 | 1996-01-16 | 公開日 | 1996-08-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy. Protein Sci., 5, 1996
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3H2Q
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![BU of 3h2q by Molmil](/molmil-images/mine/3h2q) | Human SOD1 H80R variant, P21 crystal form | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J. | 登録日 | 2009-04-14 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding
and Compromised Post-translational Modification by the Copper Chaperone CCS To be Published
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3H0C
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![BU of 3h0c by Molmil](/molmil-images/mine/3h0c) | Crystal Structure of Human Dipeptidyl Peptidase IV (CD26) in Complex with a Reversed Amide Inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide | 著者 | Nordhoff, S, Cerezo-Galvez, S, Deppe, H, Hill, O, Lopez-Canet, M, Rummey, C, Thiemann, M, Matassa, V.G, Edwards, P.J, Feurer, A. | 登録日 | 2009-04-09 | 公開日 | 2009-06-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Discovery of b-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV To be Published
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4AGG
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![BU of 4agg by Molmil](/molmil-images/mine/4agg) | Structure of a tetrameric galectin from Cinachyrella sp. (Ball sponge) | 分子名称: | CHLORIDE ION, GALECTIN | 著者 | Freymann, D.M, Focia, P.J, Sakai, R, Swanson, G.T. | 登録日 | 2012-01-27 | 公開日 | 2012-08-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Structure of a Tetrameric Galectin from Cinachyrella Sp. (Ball Sponge). Acta Crystallogr.,Sect.D, 68, 2012
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4ALI
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![BU of 4ali by Molmil](/molmil-images/mine/4ali) | Crystal structure of S. aureus FabI in complex with NADP and triclosan (P1) | 分子名称: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | 登録日 | 2012-03-04 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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3ZDC
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![BU of 3zdc by Molmil](/molmil-images/mine/3zdc) | Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, potassium and calcium | 分子名称: | 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ... | 著者 | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | 登録日 | 2012-11-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases Nucleic Acids Res., 41, 2013
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6GWN
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![BU of 6gwn by Molmil](/molmil-images/mine/6gwn) | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) | 分子名称: | Plasminogen activator inhibitor 1, VHH-2g-42, VHH-2w-64 | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2018-06-25 | 公開日 | 2020-01-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
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3CD4
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![BU of 3cd4 by Molmil](/molmil-images/mine/3cd4) | |
6H2D
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![BU of 6h2d by Molmil](/molmil-images/mine/6h2d) | |
1DJD
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![BU of 1djd by Molmil](/molmil-images/mine/1djd) | THE SOLUTION STRUCTURE OF A NON-BAY REGION 11R-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE | 分子名称: | 8,9,10,11-TETRAHYDRO-BENZO[A]ANTHRACENE-8,9,10-TRIOL, DNA(5'-D(*CT*GT*GT*AT*CT*AT*AT*GT*AT*AT*G)-3'), DNA(5'-D(*CT*TT*TT*CT*TT*TT*GT*TT*CT*CT*G)-3') | 著者 | Li, Z, Kim, H.Y, Tamura, P.J, Harris, C.M, Harris, T.M, Stone, M.P. | 登録日 | 1999-12-02 | 公開日 | 1999-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Role of a polycyclic aromatic hydrocarbon bay region ring in modulating DNA adduct structure: the non-bay region (8S,9R,10S, 11R)-N(6)-[11-(8,9,10,11-tetrahydro-8,9, 10-trihydroxybenz[a]anthracenyl)]-2' -deoxyadenosyl adduct in codon 61 of the human N-ras protooncogene Biochemistry, 38, 1999
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6GRK
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![BU of 6grk by Molmil](/molmil-images/mine/6grk) | |
3GQF
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![BU of 3gqf by Molmil](/molmil-images/mine/3gqf) | |
3GZP
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![BU of 3gzp by Molmil](/molmil-images/mine/3gzp) | |
4ALK
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![BU of 4alk by Molmil](/molmil-images/mine/4alk) | Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol | 分子名称: | 5-ETHYL-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | 登録日 | 2012-03-04 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
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