4A7X
| Crystal structure of uridylate kinase from Helicobacter pylori | Descriptor: | URIDINE-5'-DIPHOSPHATE, URIDYLATE KINASE | Authors: | Chu, C.H, Liu, M.H, Chen, P.C, Sun, Y.J. | Deposit date: | 2011-11-15 | Release date: | 2012-06-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structures of Helicobacter Pylori Uridylate Kinase: Insight Into Release of the Product Udp Acta Crystallogr.,Sect.D, 68, 2012
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1IQD
| Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab. | Descriptor: | HUMAN FACTOR VIII, HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN, HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN | Authors: | Spiegel Jr, P.C, Jacquemin, M, Saint-Remy, J.M, Stoddard, B.L, Pratt, K.P. | Deposit date: | 2001-07-21 | Release date: | 2001-08-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII. Blood, 98, 2001
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2VCN
| Structure of isoniazid (INH) bound to cytosolic soybean ascorbate peroxidase mutant W41A | Descriptor: | 4-(DIAZENYLCARBONYL)PYRIDINE, ASCORBATE PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Metcalfe, C.L, Macdonald, I.K, Brown, K.A, Raven, E.L, Moody, P.C.E. | Deposit date: | 2007-09-25 | Release date: | 2007-12-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem., 283, 2008
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2V2E
| Structure of isoniazid (INH) bound to cytochrome c peroxidase mutant N184R Y36A | Descriptor: | 4-(DIAZENYLCARBONYL)PYRIDINE, CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Metcalfe, C.L, Macdonald, I.K, Brown, K.A, Raven, E.L, Moody, P.C.E. | Deposit date: | 2007-06-05 | Release date: | 2007-12-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem., 283, 2008
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4ATO
| New insights into the mechanism of bacterial Type III toxin-antitoxin systems: selective toxin inhibition by a non-coding RNA pseudoknot | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, TOXI, TOXN | Authors: | Short, F.L, Pei, X.Y, Blower, T.R, Ong, S.L, Luisi, B.F, Salmond, G.P.C. | Deposit date: | 2012-05-09 | Release date: | 2012-12-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Selectivity and Self-Assembly in the Control of a Bacterial Toxin by an Antitoxic Noncoding RNA Pseudoknot. Proc.Natl.Acad.Sci.USA, 110, 2013
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5SW4
| Crystal structure of native catalase-peroxidase KatG at pH8.0 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ... | Authors: | Loewen, P.C. | Deposit date: | 2016-08-08 | Release date: | 2016-08-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases. EMBO Rep., 6, 2005
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2X72
| CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE. | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ACETATE ION, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | Authors: | Standfuss, J, Edwards, P.C, Dantona, A, Fransen, M, Xie, G, Oprian, D.D, Schertler, G.F.X. | Deposit date: | 2010-02-22 | Release date: | 2011-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin Nature, 471, 2011
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5SYL
| B. pseudomallei KatG with KCN bound | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, CYANIDE ION, ... | Authors: | Loewen, P.C. | Deposit date: | 2016-08-11 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of B. pseudomallei KatG with cyanide bound To be published
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1LHZ
| Structure of a Human Bence-Jones Dimer Crystallized in U.S. Space Shuttle Mission STS-95: 293K | Descriptor: | IMMUNOGLOBULIN LAMBDA LIGHT CHAIN | Authors: | Terzyan, S.S, DeWitt, C.R, Ramsland, P.A, Bourne, P.C, Edmundson, A.B. | Deposit date: | 2002-04-17 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Comparison of the three-dimensional structures of a human Bence-Jones dimer
crystallized on Earth and aboard US Space Shuttle Mission STS-95 J.MOL.RECOG., 16, 2003
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5SX2
| Crystal structure of the D141E mutant of B. pseudomallei KatG at pH 8.0. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ... | Authors: | Loewen, P.C. | Deposit date: | 2016-08-09 | Release date: | 2016-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Two alternative substrate paths for compound I formation and reduction in catalase-peroxidase KatG from Burkholderia pseudomallei. Proteins, 66, 2007
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5SYJ
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5SYY
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1HRN
| HIGH RESOLUTION CRYSTAL STRUCTURES OF RECOMBINANT HUMAN RENIN IN COMPLEX WITH POLYHYDROXYMONOAMIDE INHIBITORS | Descriptor: | (2R,4S,5S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(cyclopropylmethyl)-4,5-dihydroxy-6-phenylhexanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, RENIN | Authors: | Tong, L, Anderson, P.C. | Deposit date: | 1995-03-31 | Release date: | 1995-06-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors. J.Mol.Biol., 250, 1995
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2WKW
| Alcaligenes esterase complexed with product analogue | Descriptor: | CARBOXYLESTERASE, GLYCEROL, SULFATE ION, ... | Authors: | Bourne, P.C, Isupov, M.N, Littlechild, J.A. | Deposit date: | 2009-06-18 | Release date: | 2009-06-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | The Atomic-Resolution Structure of a Novel Bacterial Esterase. Structure, 8, 2000
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1KV8
| Crystal Structure of 3-Keto-L-Gulonate 6-Phosphate Decarboxylase | Descriptor: | 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, MAGNESIUM ION, PHOSPHATE ION | Authors: | Wise, E, Yew, W.S, Babbitt, P.C, Gerlt, J.A, Rayment, I. | Deposit date: | 2002-01-25 | Release date: | 2002-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry, 41, 2002
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2WD4
| Ascorbate Peroxidase as a heme oxygenase: w41A variant product with t-butyl peroxide | Descriptor: | 3-[2-[[3-(2-CARBOXYETHYL)-5-[[3-ETHENYL-4-METHYL-5-[(2-METHYLPROPAN-2-YL)OXY]-1H-PYRROL-2-YL]METHYL]-4-METHYL-1H-PYRROL -2-YL]METHYL]-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXO-PYRROL-2-YLIDENE)METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC ACID, ASCORBATE PEROXIDASE, FE (III) ION, ... | Authors: | Badyal, S.K, Metcalfe, C.L, Gumiero, A, Raven, E.L, Moody, P.C.E. | Deposit date: | 2009-03-19 | Release date: | 2009-04-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Evidence for Heme Oxygenase Activity in a Heme Peroxidase. Biochemistry, 48, 2009
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5V2D
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1LGV
| Structure of a Human Bence-Jones Dimer Crystallized in U.S. Space Shuttle Mission STS-95: 100K | Descriptor: | IMMUNOGLOBULIN LAMBDA LIGHT CHAIN | Authors: | Terzyan, S.S, DeWitt, C.R, Ramsland, P.A, Bourne, P.C, Edmundson, A.B. | Deposit date: | 2002-04-16 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Comparison of the three-dimensional structures of a human Bence-Jones dimer
crystallized on Earth and aboard US Space Shuttle Mission STS-95 J.MOL.RECOG., 16, 2003
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1LHF
| HUMAN ALPHA-THROMBIN COMPLEXED WITH AC-(D)PHE-PRO-BORO-HOMOLYS-OH | Descriptor: | AC-(D)PHE-PRO-BOROHOMOLYS-OH, ALPHA-THROMBIN, HIRUDIN | Authors: | Weber, P.C, Lee, S.L, Lewandowski, F.A, Schadt, M.C, Chang, C.H, Kettner, C.A. | Deposit date: | 1994-12-27 | Release date: | 1996-11-08 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Kinetic and crystallographic studies of thrombin with Ac-(D)Phe-Pro-boroArg-OH and its lysine, amidine, homolysine, and ornithine analogs. Biochemistry, 34, 1995
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2X07
| cytochrome c peroxidase: engineered ascorbate binding site | Descriptor: | Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Murphy, E.J, Metcalfe, C.L, Gumiero, A, Raven, E.L, Moody, P.C.E. | Deposit date: | 2009-12-07 | Release date: | 2010-11-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase. Biochemistry, 47, 2008
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2WRY
| Crystal structure of chicken cytokine interleukin 1 beta | Descriptor: | INTERLEUKIN-1BETA | Authors: | Lu, W.S, Cheng, C.S, Lyu, P.C, Lee, L.H, Wang, W.C, Yin, H.S. | Deposit date: | 2009-09-03 | Release date: | 2010-09-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human. Mol.Immunol., 48, 2011
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2V6H
| Crystal structure of the C1 domain of cardiac myosin binding protein-C | Descriptor: | MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE | Authors: | Govata, L, Carpenter, L, Da Fonseca, P.C.A, Helliwell, J.R, Rizkallah, P.J, Flashman, E, Chayen, N.E, Redwood, C, Squire, J.M. | Deposit date: | 2007-07-18 | Release date: | 2008-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy. J. Mol. Biol., 378, 2008
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1L3L
| Crystal structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA | Descriptor: | 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*GP*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP*CP*TP*GP*CP*AP*CP*AP*TP*C)-3', Transcriptional activator protein traR | Authors: | Zhang, R, Pappas, T, Brace, J.L, Miller, P.C, Oulmassov, T, Molyneaux, J.M, Anderson, J.C, Bashkin, J.K, Winans, S.C, Joachimiak, A. | Deposit date: | 2002-02-27 | Release date: | 2002-07-03 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature, 417, 2002
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1L2T
| Dimeric Structure of MJ0796, a Bacterial ABC Transporter Cassette | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Hypothetical ABC transporter ATP-binding protein MJ0796, ISOPROPYL ALCOHOL, ... | Authors: | Smith, P.C, Karpowich, N, Rosen, J, Hunt, J.F. | Deposit date: | 2002-02-24 | Release date: | 2002-07-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol.Cell, 10, 2002
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2W1O
| NMR structure of dimerization domain of human ribosomal protein P2 | Descriptor: | 60S ACIDIC RIBOSOMAL PROTEIN P2 | Authors: | Lee, K.M, Chan, D.S, Sze, K.H, Zhu, G, Shaw, P.C, Wong, K.B. | Deposit date: | 2008-10-20 | Release date: | 2009-11-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Dimerization Domain of Ribosomal Protein P2 Provides Insights for the Structural Organization of Eukaryotic Stalk. Nucleic Acids Res., 38, 2010
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