8IYO
| Crystal structure of a protein acetyltransferase, HP0935, acetyl-CoA bound form | Descriptor: | ACETYL COENZYME *A, N-acetyltransferase domain-containing protein | Authors: | Dadireddy, V, Mahanta, P, Kumar, A, Desirazu, R.N, Ramakumar, S. | Deposit date: | 2023-04-05 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a protein acetyltransferase, HP0935, acetyl-CoA bound form To be published
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3MLE
| Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori cocrystallized with ATP | Descriptor: | 8-aminooctanoic acid, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Nicholls, R, Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Joachimiak, A, Murshudov, G, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-04-16 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
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3MLX
| Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with an MN V3 peptide | Descriptor: | HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain | Authors: | Kong, X.-P. | Deposit date: | 2010-04-18 | Release date: | 2010-07-14 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol., 17, 2010
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3MM8
| Dissimilatory sulfite reductase nitrate complex | Descriptor: | IRON/SULFUR CLUSTER, NITRATE ION, SIROHEME, ... | Authors: | Parey, K, Warkentin, E, Kroneck, P.M.H, Ermler, U. | Deposit date: | 2010-04-19 | Release date: | 2010-07-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Reaction cycle of the dissimilatory sulfite reductase from Archaeoglobus fulgidus. Biochemistry, 49, 2010
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6XXW
| Structure of beta-D-Glucuronidase for Dictyoglomus thermophilum. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucuronidase, ... | Authors: | Lafite, P, Daniellou, R. | Deposit date: | 2020-01-28 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Thioglycoligation of aromatic thiols using a natural glucuronide donor. Org.Biomol.Chem., 18, 2020
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5TNZ
| HtrA2 S142D mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, Serine protease HTRA2, ... | Authors: | Macedo-Ribeiro, S, Merski, M, Pereira, P.J.B. | Deposit date: | 2016-10-15 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death Dis, 8, 2017
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1JQA
| Bacillus stearothermophilus glycerol dehydrogenase complex with glycerol | Descriptor: | GLYCEROL, Glycerol Dehydrogenase, ZINC ION | Authors: | Ruzheinikov, S.N, Burke, J, Sedelnikova, S, Baker, P.J, Taylor, R, Bullough, P.A, Muir, N.M, Gore, M.G, Rice, D.W. | Deposit date: | 2001-08-04 | Release date: | 2001-10-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase. Structure, 9, 2001
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2W1H
| Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity | Descriptor: | CELL DIVISION PROTEIN KINASE 2, N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE | Authors: | Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. | Deposit date: | 2008-10-17 | Release date: | 2009-01-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity. J.Med.Chem., 52, 2009
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2VTA
| Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H- pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design. | Descriptor: | 1H-indazole, CELL DIVISION PROTEIN KINASE 2, GLYCEROL | Authors: | Wyatt, P.G, Woodhead, A.J, Boulstridge, J.A, Berdini, V, Carr, M.G, Cross, D.M, Danillon, D, Davis, D.J, Devine, L.A, Early, T.R, Feltell, R.E, Lewis, E.J, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Reule, M, Saxty, G, Seavers, L.C.A, Smith, D, Squires, M.S, Trewartha, G, Walker, M.T, Woolford, A.J. | Deposit date: | 2008-05-13 | Release date: | 2008-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of N-(4-Piperidinyl)-4-(2,6-Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design. J.Med.Chem., 51, 2008
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1QQ3
| THE SOLUTION STRUCTURE OF THE HEME BINDING VARIANT ARG98CYS OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562 | Descriptor: | CYTOCHROME B562, HEME B/C | Authors: | Arnesano, F, Banci, L, Bertini, I, Ciofi-Baffoni, S, Barker, P.D, Woodyear, T. | Deposit date: | 1999-06-10 | Release date: | 2000-05-24 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Structural consequences of b- to c-type heme conversion in oxidized Escherichia coli cytochrome b562. Biochemistry, 39, 2000
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2AGA
| De-ubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain | Descriptor: | Machado-Joseph disease protein 1 | Authors: | Mao, Y, Senic-Matuglia, F, Di Fiore, P, Polo, S, Hodsdon, M.E, De Camilli, P. | Deposit date: | 2005-07-26 | Release date: | 2005-08-30 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain. Proc.Natl.Acad.Sci.Usa, 102, 2005
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5MUF
| Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in its enzymatically active dodecameric form induced by the presence of the N-terminal WDPNWD motif | Descriptor: | PHOSPHATE ION, Serine/threonine-protein phosphatase PGAM5, mitochondrial | Authors: | Chaikuad, A, Alfano, I, Picaud, S, Filippakopoulos, P, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2017-01-13 | Release date: | 2017-07-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly. Structure, 25, 2017
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3ZS0
| Human Myeloperoxidase inactivated by TX2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-FLUOROBENZYL)-2-THIOXO-1,2,3,7-TETRAHYDRO-6H-PURIN-6-ONE, ACETATE ION, ... | Authors: | Tiden, A.K, Sjogren, T, Svensson, M, Bernlind, A, Senthilmohan, R, Auchere, F, Norman, H, Markgren, P.O, Gustavsson, S, Schmidt, S, Lundquist, S, Forbes, L.V, Magon, N.J, Jameson, G.N, Eriksson, H, Kettle, A.J. | Deposit date: | 2011-06-21 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | 2-Thioxanthines are Mechanism-Based Inactivators of Myeloperoxidase that Block Oxidative Stress During Inflammation. J.Biol.Chem., 286, 2011
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3ZUP
| The 3-dimensional structure of MpgP from Thermus thermophilus HB27, in complex with the alpha-mannosylglycerate and orthophosphate reaction products. | Descriptor: | (2R)-3-hydroxy-2-(alpha-D-mannopyranosyloxy)propanoic acid, MAGNESIUM ION, MANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE, ... | Authors: | Goncalves, S, Esteves, A.M, Santos, H, Borges, N, Matias, P.M. | Deposit date: | 2011-07-19 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.804 Å) | Cite: | The Three-Dimensional Structure of Mannosyl-3-Phosphoglycerate Phosphatase from Thermus Thermophilus Hb27: A New Member of the Haloalkanoic Acid Dehalogenase Superfamily. Biochemistry, 50, 2011
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2W3J
| Structure of a family 35 carbohydrate binding module from an environmental isolate | Descriptor: | CALCIUM ION, CARBOHYDRATE BINDING MODULE | Authors: | Montainer, C, Flint, J, Gloster, T.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | Deposit date: | 2008-11-12 | Release date: | 2009-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function. Proc.Natl.Acad.Sci.USA, 106, 2009
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1JZD
| DsbC-DsbDalpha complex | Descriptor: | thiol:disulfide interchange protein dsbc, thiol:disulfide interchange protein dsbd | Authors: | Haebel, P.W, Goldstone, D, Katzen, F, Beckwith, J, Metcalf, P. | Deposit date: | 2001-09-15 | Release date: | 2003-03-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Disulfide Bond Isomerase DsbC is Activated by an
Immunoglobulin-fold Thiol Oxidoreductase: Crystal structure of the
DsbC-DsbDalpha complex. Embo J., 21, 2002
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1ADX
| FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, 14 STRUCTURES | Descriptor: | THROMBOMODULIN | Authors: | Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A. | Deposit date: | 1997-02-18 | Release date: | 1997-12-24 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern. J.Mol.Biol., 273, 1997
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2XI1
| Crystal structure of the HIV-1 Nef sequenced from a patient's sample | Descriptor: | NEF | Authors: | Yadav, G.P, Singh, P, Gupta, S, Tripathi, A.K, Tripathi, R.K, Ramachandran, R. | Deposit date: | 2010-06-25 | Release date: | 2011-08-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef. Plos One, 6, 2011
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2BAA
| THE REFINED CRYSTAL STRUCTURE OF AN ENDOCHITINASE FROM HORDEUM VULGARE L. SEEDS TO 1.8 ANGSTROMS RESOLUTION | Descriptor: | ENDOCHITINASE (26 KD) | Authors: | Hart, P.J, Pfluger, H.D, Monzingo, A.F, Ready, M.P, Ernst, S.R, Hollis, T, Robertus, J.D. | Deposit date: | 1995-01-26 | Release date: | 1996-01-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 A resolution. J.Mol.Biol., 248, 1995
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6XCR
| NMR structure of Ost4 in DPC micelles | Descriptor: | Oligosaccharyltransferase | Authors: | Chaudhary, B.P. | Deposit date: | 2020-06-09 | Release date: | 2021-02-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR and MD simulations reveal the impact of the V23D mutation on the function of yeast oligosaccharyltransferase subunit Ost4. Glycobiology, 31, 2021
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7RFA
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1KX2
| Minimized average structure of a mono-heme ferrocytochrome c from Shewanella putrefaciens | Descriptor: | HEME C, mono-heme c-type cytochrome ScyA | Authors: | Bartalesi, I, Bertini, I, Hajieva, P, Rosato, A, Vasos, P.R. | Deposit date: | 2002-01-30 | Release date: | 2002-02-13 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of a monoheme ferrocytochrome c from Shewanella putrefaciens and structural analysis of sequence-similar proteins: functional implications. Biochemistry, 41, 2002
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4XVP
| X-ray structure of bGFP-C / EGFP complex | Descriptor: | BGFP-C, Green fluorescent protein | Authors: | Chevrel, A, Urvoas, A, Li de la Sierra-Gallay, I, Van Tilbeurgh, H, Minard, P, Valerio-Lepiniec, M. | Deposit date: | 2015-01-27 | Release date: | 2015-08-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Specific GFP-binding artificial proteins ( alpha Rep): a new tool for in vitro to live cell applications. Biosci.Rep., 35, 2015
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8HX1
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8HX0
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