6YU2
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![BU of 6yu2 by Molmil](/molmil-images/mine/6yu2) | Crystal structure of MhsT in complex with L-isoleucine | Descriptor: | ISOLEUCINE, SODIUM ION, Sodium-dependent transporter, ... | Authors: | Focht, D, Neumann, C, Lyons, J, Eguskiza Bilbao, A, Blunck, R, Malinauskaite, L, Schwarz, I.O, Javitch, J.A, Quick, M, Nissen, P. | Deposit date: | 2020-04-25 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition. Embo J., 40, 2021
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4O21
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![BU of 4o21 by Molmil](/molmil-images/mine/4o21) | Product complex of metal-free PKAc, ATP-gamma-S and SP20. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha | Authors: | Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S. | Deposit date: | 2013-12-16 | Release date: | 2014-05-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
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3UIR
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![BU of 3uir by Molmil](/molmil-images/mine/3uir) | Crystal structure of the plasmin-textilinin-1 complex | Descriptor: | Plasmin light chain B, SULFATE ION, Textilinin-1 | Authors: | Guddat, L.W, Millers, E.K, de jersey, J, Lavin, M.F, Masci, P.M. | Deposit date: | 2011-11-05 | Release date: | 2012-12-26 | Last modified: | 2013-07-17 | Method: | X-RAY DIFFRACTION (2.777 Å) | Cite: | The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake. Plos One, 8, 2013
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3UF1
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![BU of 3uf1 by Molmil](/molmil-images/mine/3uf1) | Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B | Descriptor: | Vimentin | Authors: | Kuzin, A, Abashidze, M, Vorobiev, S.M, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-10-31 | Release date: | 2011-11-30 | Last modified: | 2013-04-24 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography. J.Biol.Chem., 287, 2012
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7QTV
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![BU of 7qtv by Molmil](/molmil-images/mine/7qtv) | Beryllium fluoride form of the Na+,K+-ATPase (E2-BeFx) | Descriptor: | 1-O-decanoyl-beta-D-tagatofuranosyl beta-D-allopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shahsavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P. | Deposit date: | 2022-01-16 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.05 Å) | Cite: | The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. J.Biol.Chem., 298, 2022
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1VZM
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![BU of 1vzm by Molmil](/molmil-images/mine/1vzm) | OSTEOCALCIN FROM FISH ARGYROSOMUS REGIUS | Descriptor: | MAGNESIUM ION, OSTEOCALCIN | Authors: | Frazao, C, Simes, D.C, Coelho, R, Alves, D, Williamson, M.K, Price, P.A, Cancela, M.L, Carrondo, M.A. | Deposit date: | 2004-05-21 | Release date: | 2004-09-10 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Evidence of a Fourth Gla Residue in Fish Osteocalcin: Biological Implications Biochemistry, 44, 2005
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4UXN
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![BU of 4uxn by Molmil](/molmil-images/mine/4uxn) | LSD1(KDM1A)-CoREST in complex with Z-Pro derivative of MC2580 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, ... | Authors: | Rodriguez, V, Valente, S, Stazi, G, Lucidi, A, Mercurio, C, Vianello, P, Ciossani, G, Mattevi, A, Botrugno, O.A, Dessanti, P, Minucci, S, Varasi, M, Mai, A. | Deposit date: | 2014-08-27 | Release date: | 2015-02-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Pyrrole- and Indole-Containing Tranylcypromine Derivatives as Novel Lysine-Specific Demethylase 1 Inhibitors Active on Cancer Cells Chemmedchem, 6, 2015
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6DD4
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![BU of 6dd4 by Molmil](/molmil-images/mine/6dd4) | Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor | Descriptor: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-dipropyl-7,8-dihydropteridin-6(5H)-one, ACETATE ION, CHLORIDE ION, ... | Authors: | dos Reis, C.V, Santiago, A.S, de Souza, G.P, Counago, R.M, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-05-09 | Release date: | 2018-05-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor To Be Published
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7QCA
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![BU of 7qca by Molmil](/molmil-images/mine/7qca) | Spraguea lophii ribosome | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | Deposit date: | 2021-11-22 | Release date: | 2022-11-30 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state Nat Microbiol, 2023
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3UEC
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![BU of 3uec by Molmil](/molmil-images/mine/3uec) | Crystal structure of human Survivin bound to histone H3 phosphorylated on threonine-3. | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Baculoviral IAP repeat-containing protein 5, ... | Authors: | Niedzialkowska, E, Porebski, P.J, Cooper, D.R, Chruszcz, M, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | Deposit date: | 2011-10-30 | Release date: | 2012-03-07 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol.Biol.Cell, 23, 2012
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6Z20
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![BU of 6z20 by Molmil](/molmil-images/mine/6z20) | Structure of the EC2 domain of CD9 in complex with nanobody 4C8 | Descriptor: | CD9 antigen, CHLORIDE ION, GLYCEROL, ... | Authors: | Oosterheert, W, Manshande, J, Pearce, N.M, Lutz, M, Gros, P. | Deposit date: | 2020-05-14 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life Sci Alliance, 3, 2020
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4O1Y
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![BU of 4o1y by Molmil](/molmil-images/mine/4o1y) | Crystal structure of Porcine Pancreatic Phospholipase A2 in complex with 1-Naphthaleneacetic acid | Descriptor: | CALCIUM ION, NAPHTHALEN-1-YL-ACETIC ACID, Phospholipase A2, ... | Authors: | Dileep, K.V, Remya, C, Tintu, I, Mandal, P.K, Karthe, P, Haridas, M, Sadasivan, C. | Deposit date: | 2013-12-16 | Release date: | 2014-01-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Porcine Pancreatic Phospholipase A2 in complex with 1-Naphthaleneacetic acid To be published
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9BKF
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![BU of 9bkf by Molmil](/molmil-images/mine/9bkf) | |
9BKL
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![BU of 9bkl by Molmil](/molmil-images/mine/9bkl) | |
1VJK
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![BU of 1vjk by Molmil](/molmil-images/mine/1vjk) | Putative molybdopterin converting factor, subunit 1 from Pyrococcus furiosus, Pfu-562899-001 | Descriptor: | molybdopterin converting factor, subunit 1 | Authors: | Chen, L, Liu, Z.J, Tempel, W, Shah, A, Lee, D, Rose, J.P, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-03-10 | Release date: | 2004-08-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Putative molybdopterin converting factor, subunit 1 from Pyrococcus furiosus, Pfu-562899-001 ' To be published
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1VQ2
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![BU of 1vq2 by Molmil](/molmil-images/mine/1vq2) | CRYSTAL STRUCTURE OF T4-BACTERIOPHAGE DEOXYCYTIDYLATE DEAMINASE, MUTANT R115E | Descriptor: | 3,4-DIHYDRO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, DEOXYCYTIDYLATE DEAMINASE, ZINC ION | Authors: | Almog, R, Maley, F, Maley, G.F, Maccoll, R, Van Roey, P. | Deposit date: | 2004-12-15 | Release date: | 2004-12-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-Dimensional Structure of the R115E Mutant of T4-Bacteriophage 2'-Deoxycytidylate Deaminase Biochemistry, 43, 2004
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9BKP
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8Z9Z
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![BU of 8z9z by Molmil](/molmil-images/mine/8z9z) | Cryo-EM structure of the insect olfactory receptor OR5-Orco heterocomplex from Acyrthosiphon pisum | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Odorant receptor, ApisOR5, ... | Authors: | Wang, Y.D, Qiu, L, Guan, Z.Y, Wang, Q, Wang, G.R, Yin, P. | Deposit date: | 2024-04-24 | Release date: | 2024-06-19 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for odorant recognition of the insect odorant receptor OR-Orco heterocomplex. Science, 384, 2024
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7LOO
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![BU of 7loo by Molmil](/molmil-images/mine/7loo) | S-adenosyl methionine transferase cocrystallized with ATP | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Jackson, C.J, Tan, L.L, Laurino, P. | Deposit date: | 2021-02-10 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases. Jacs Au, 1, 2021
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4V3O
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![BU of 4v3o by Molmil](/molmil-images/mine/4v3o) | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | Descriptor: | ACETATE ION, CALCIUM ION, YIII_M5_AII | Authors: | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | Deposit date: | 2014-10-20 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
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7LXT
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![BU of 7lxt by Molmil](/molmil-images/mine/7lxt) | Structure of Plasmodium falciparum 20S proteasome with bound bortezomib | Descriptor: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | Authors: | Morton, C.J, Metcalfe, R.D, Liu, B, Xie, S.C, Hanssen, E, Leis, A.P, Tilley, L, Griffin, M.D.W. | Deposit date: | 2021-03-05 | Release date: | 2021-09-22 | Last modified: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc.Natl.Acad.Sci.USA, 118, 2021
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4O5Q
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![BU of 4o5q by Molmil](/molmil-images/mine/4o5q) | Crystal Structure of the Alkylhydroperoxide Reductase AhpF from Escherichia coli | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkyl hydroperoxide reductase subunit F, CADMIUM ION, ... | Authors: | Dip, P.V, Kamariah, N, Manimekalai, M.S.S, Balakrishna, A.M, Gruber, G. | Deposit date: | 2013-12-20 | Release date: | 2014-11-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli Acta Crystallogr.,Sect.D, 70, 2014
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7LXU
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![BU of 7lxu by Molmil](/molmil-images/mine/7lxu) | Structure of Plasmodium falciparum 20S proteasome with bound MPI-5 | Descriptor: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | Authors: | Metcalfe, R.D, Morton, C.J, Xie, S.C, Liu, B, Hanssen, E, Leis, A.P, Tilley, L, Griffin, M.D.W. | Deposit date: | 2021-03-05 | Release date: | 2021-09-22 | Last modified: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc.Natl.Acad.Sci.USA, 118, 2021
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3GVW
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![BU of 3gvw by Molmil](/molmil-images/mine/3gvw) | Single-chain UROD F217Y (YF) mutation | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | Deposit date: | 2009-03-31 | Release date: | 2009-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J.Mol.Biol., 389, 2009
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3UDG
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![BU of 3udg by Molmil](/molmil-images/mine/3udg) | Structure of Deinococcus radiodurans SSB bound to ssDNA | Descriptor: | 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', Single-stranded DNA-binding protein, THYMIDINE-5'-PHOSPHATE | Authors: | George, N.P, Ngo, K.V, Chitteni-Patu, S, Norais, C.A, Battista, J.R, Cox, M.M, Keck, J.L. | Deposit date: | 2011-10-28 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Cellular Dynamics of Deinococcus radiodurans Single-stranded DNA (ssDNA)-binding Protein (SSB)-DNA Complexes. J.Biol.Chem., 287, 2012
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