3TCF
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![BU of 3tcf by Molmil](/molmil-images/mine/3tcf) | Crystal structure of E. coli OppA complexed with endogenous ligands | 分子名称: | Endogenous peptide, Periplasmic oligopeptide-binding protein | 著者 | Klepsch, M.M, Kovermann, M, Low, C, Balbach, J, de Gier, J.W, Slotboom, D.J, Berntsson, R.P.-A. | 登録日 | 2011-08-09 | 公開日 | 2011-10-12 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Escherichia coli peptide binding protein OppA has a preference for positively charged peptides. J.Mol.Biol., 414, 2011
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4ENV
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![BU of 4env by Molmil](/molmil-images/mine/4env) | Structure of the S234I variant of E. coli KatE | 分子名称: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Loewen, P.C, Jha, V. | 登録日 | 2012-04-13 | 公開日 | 2012-05-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli. Arch.Biochem.Biophys., 526, 2012
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6EC8
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1DCM
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![BU of 1dcm by Molmil](/molmil-images/mine/1dcm) | STRUCTURE OF UNPHOSPHORYLATED FIXJ-N WITH AN ATYPICAL CONFORMER (MONOMER A) | 分子名称: | MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN FIXJ | 著者 | Gouet, P, Fabry, B, Guillet, V, Birck, C, Mourey, L, Kahn, D, Samama, J.P. | 登録日 | 1999-11-05 | 公開日 | 2000-11-08 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural transitions in the FixJ receiver domain. Structure Fold.Des., 7, 1999
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6CAW
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3TCG
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![BU of 3tcg by Molmil](/molmil-images/mine/3tcg) | Crystal structure of E. coli OppA complexed with the tripeptide KGE | 分子名称: | KGE Peptide, Periplasmic oligopeptide-binding protein | 著者 | Klepsch, M.M, Kovermann, M, Low, C, Balbach, J, de Gier, J.W, Slotboom, D.J, Berntsson, R.P.-A. | 登録日 | 2011-08-09 | 公開日 | 2011-10-12 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Escherichia coli peptide binding protein OppA has a preference for positively charged peptides. J.Mol.Biol., 414, 2011
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7UAW
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![BU of 7uaw by Molmil](/molmil-images/mine/7uaw) | Structure of Clostridium botulinum prophage Tad1 in complex with 1''-2' gcADPR | 分子名称: | (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione, ABC transporter ATPase | 著者 | Lu, A, Leavitt, A, Yirmiya, E, Amitai, G, Garb, J, Morehouse, B.R, Hobbs, S.J, Sorek, R, Kranzusch, P.J. | 登録日 | 2022-03-14 | 公開日 | 2022-10-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Viruses inhibit TIR gcADPR signalling to overcome bacterial defence. Nature, 611, 2022
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6V1I
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![BU of 6v1i by Molmil](/molmil-images/mine/6v1i) | Cryo-EM reconstruction of the thermophilic bacteriophage P74-26 small terminase- symmetric | 分子名称: | Small terminase protein | 著者 | Hayes, J.A, Hilbert, B.J, Gaubitz, C, Stone, N.P, Kelch, B.A. | 登録日 | 2019-11-20 | 公開日 | 2020-02-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry. J.Biol.Chem., 295, 2020
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8DPZ
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1DGC
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8DTK
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3KCF
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3FV3
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![BU of 3fv3 by Molmil](/molmil-images/mine/3fv3) | Secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A | 分子名称: | GLYCEROL, SULFATE ION, Sapp1p-secreted aspartic protease 1, ... | 著者 | Dostal, J, Brynda, J, Hruskova-Heidingsfeldova, O, Sieglova, I, Pichova, I, Rezacova, P. | 登録日 | 2009-01-15 | 公開日 | 2009-05-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A J.Struct.Biol., 167, 2009
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3KCJ
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6EQ4
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![BU of 6eq4 by Molmil](/molmil-images/mine/6eq4) | MTH1 in complex with fragment 8 | 分子名称: | 4-(3-fluoranylpyridin-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2017-10-12 | 公開日 | 2018-10-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Ligand retargeting by binding site analogy. Eur.J.Med.Chem., 175, 2019
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6EQ6
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![BU of 6eq6 by Molmil](/molmil-images/mine/6eq6) | MTH1 in complex with fragment 1 | 分子名称: | 3-pyrrolidin-1-ylquinoxalin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2017-10-12 | 公開日 | 2018-10-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Ligand retargeting by binding site analogy. Eur.J.Med.Chem., 175, 2019
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6WYW
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![BU of 6wyw by Molmil](/molmil-images/mine/6wyw) | Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 4.5 | 分子名称: | ASPARTIC ACID, Glutaminase-asparaginase | 著者 | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | 登録日 | 2020-05-13 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep, 10, 2020
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6I6J
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7UN9
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![BU of 7un9 by Molmil](/molmil-images/mine/7un9) | SfSTING with c-di-GMP double fiber | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12 | 著者 | Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. | 登録日 | 2022-04-09 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
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4R2X
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![BU of 4r2x by Molmil](/molmil-images/mine/4r2x) | Unique conformation of uridine and asymmetry of the hexameric molecule revealed in the high-resolution structures of Shewanella oneidensis uridine phosphorylase in the free form and in complex with uridine | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Safonova, T.N, Mordkovich, N.N, Manuvera, V.A, Veiko, V.P, Popov, V.O, Polyakov, K.M. | 登録日 | 2014-08-13 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.93 Å) | 主引用文献 | High-syn conformation of uridine and asymmetry of the hexameric molecule revealed in the high-resolution structures of Shewanella oneidensis MR-1 uridine phosphorylase in the free form and in complex with uridine. Acta Crystallogr.,Sect.D, 70, 2014
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6CMS
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![BU of 6cms by Molmil](/molmil-images/mine/6cms) | Closed structure of active SHP2 mutant E76K bound to SHP099 inhibitor | 分子名称: | 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Padua, R.A.P, Sun, Y, Marko, I, Pitsawong, W, Kern, D. | 登録日 | 2018-03-06 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2. Nat Commun, 9, 2018
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5O0J
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![BU of 5o0j by Molmil](/molmil-images/mine/5o0j) | ADP-dependent glucokinase from Pyrococcus horikoshii | 分子名称: | 8-BROMO-ADENOSINE-5'-MONOPHOSPHATE, ADP-dependent glucokinase, alpha-D-glucopyranose | 著者 | Grudnik, P, Dubin, G. | 登録日 | 2017-05-16 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide. J. Biol. Chem., 293, 2018
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2JYV
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![BU of 2jyv by Molmil](/molmil-images/mine/2jyv) | Human Granulin F | 分子名称: | Granulin-2 | 著者 | Tolkatchev, D, Wang, P, Chen, Z, Xu, P, Ni, F. | 登録日 | 2007-12-19 | 公開日 | 2008-04-22 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities. Protein Sci., 17, 2008
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6WUQ
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![BU of 6wuq by Molmil](/molmil-images/mine/6wuq) | Crystal structure of AjiA1 in apo form | 分子名称: | AjiA1, MAGNESIUM ION, ZINC ION | 著者 | Paiva, F.C.R, Chan, K, Leadlay, P, Dias, M.V.B. | 登録日 | 2020-05-05 | 公開日 | 2020-12-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | The crystal structure of AjiA1 reveals a novel structural motion mechanism in the adenylate-forming enzyme family Acta Crystallogr.,Sect.D, 76, 2020
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4JPO
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![BU of 4jpo by Molmil](/molmil-images/mine/4jpo) | 5A resolution structure of Proteasome Assembly Chaperone Hsm3 in complex with a C-terminal fragment of Rpt1 | 分子名称: | 26S protease regulatory subunit 7 homolog, DNA mismatch repair protein HSM3 | 著者 | Lovell, S, Battaile, K.P, Singh, R, Roelofs, J. | 登録日 | 2013-03-19 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Reconfiguration of the proteasome during chaperone-mediated assembly. Nature, 497, 2013
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