6X5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x5e by Molmil](/molmil-images/mine/6x5e) | |
6X5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x5j by Molmil](/molmil-images/mine/6x5j) | Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors | 分子名称: | 2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, CITRIC ACID, Coagulation factor IX, ... | 著者 | Jayne, C.L, Andreani, T, Chan, T, Chelliah, M.V, Clasby, M.C, Dwyer, M, Eagen, K.A, Fried, S, Greenlee, W.J, Guo, Z, Hawes, B, Hruza, A, Ingram, R, Keertikar, K.M, Neelamkavil, S, Reichert, P, Xia, Y, Chackalamannil, S. | 登録日 | 2020-05-26 | 公開日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (2.513 Å) | 主引用文献 | Discovery of hydroxy pyrimidine Factor IXa inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
|
|
6X5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x5l by Molmil](/molmil-images/mine/6x5l) | Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors | 分子名称: | 4-{[5-hydroxy-6-(4-methylphenyl)pyrimidin-4-yl]amino}benzene-1-carboximidamide, CITRIC ACID, Coagulation factor IX, ... | 著者 | Jayne, C.L, Andreani, T, Chan, T, Chelliah, M.V, Clasby, M.C, Dwyer, M, Eagen, K.A, Fried, S, Greenlee, W.J, Guo, Z, Hawes, B, Hruza, A, Ingram, R, Keertikar, K.M, Neelamkavil, S, Reichert, P, Xia, Y, Chackalamannil, S. | 登録日 | 2020-05-26 | 公開日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (2.246 Å) | 主引用文献 | Discovery of hydroxy pyrimidine Factor IXa inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
|
|
8D30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d30 by Molmil](/molmil-images/mine/8d30) | Crystal structure of the human COPB2 WD-domains | 分子名称: | 1,2-ETHANEDIOL, Coatomer subunit beta' | 著者 | Zeng, H, Dong, A, Hutchinson, A, Seitova, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2022-05-31 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the human COPB2 WD-domains To Be Published
|
|
3K1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k1f by Molmil](/molmil-images/mine/3k1f) | Crystal structure of RNA Polymerase II in complex with TFIIB | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P. | 登録日 | 2009-09-27 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | RNA polymerase II-TFIIB structure and mechanism of transcription initiation. Nature, 462, 2009
|
|
2B8S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b8s by Molmil](/molmil-images/mine/2b8s) | Structure of HIV-1(MAL) genomic RNA DIS | 分子名称: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, SODIUM ION, ... | 著者 | Ennifar, E, Walter, P, Ehresmann, B, Ehresmann, C, Dumas, P. | 登録日 | 2005-10-10 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site NAT.STRUCT.BIOL., 8, 2001
|
|
6WBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wbx by Molmil](/molmil-images/mine/6wbx) | Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 1 | 分子名称: | CALCIUM ION, DUF3367 domain-containing protein | 著者 | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | 登録日 | 2020-03-27 | 公開日 | 2020-05-13 | 最終更新日 | 2020-06-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
|
|
6MYY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6myy by Molmil](/molmil-images/mine/6myy) | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | 登録日 | 2018-11-02 | 公開日 | 2018-11-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
|
|
8UWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uwb by Molmil](/molmil-images/mine/8uwb) | Crystal structure of PP2A PPP2R1A-PPP2CA-PPP2R5E phosphatase. | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | 著者 | Wachter, F, Nowak, R.P, Fischer, E.S. | 登録日 | 2023-11-06 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural characterization of methylation-independent PP2A assembly guides alphafold2Multimer prediction of family-wide PP2A complexes. J.Biol.Chem., 300, 2024
|
|
1TGL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tgl by Molmil](/molmil-images/mine/1tgl) | A SERINE PROTEASE TRIAD FORMS THE CATALYTIC CENTRE OF A TRIACYLGLYCEROL LIPASE | 分子名称: | TRIACYL-GLYCEROL ACYLHYDROLASE | 著者 | Brady, L, Brzozowski, A.M, Derewenda, Z.S, Dodson, E.J, Dodson, G.G, Tolley, S.P, Turkenburg, J.P, Christiansen, L, Huge-Jensen, B, Norskov, L, Thim, L. | 登録日 | 1990-02-05 | 公開日 | 1990-10-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A serine protease triad forms the catalytic centre of a triacylglycerol lipase. Nature, 343, 1990
|
|
6WBY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wby by Molmil](/molmil-images/mine/6wby) | Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 2 | 分子名称: | CALCIUM ION, DUF3367 domain-containing protein | 著者 | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | 登録日 | 2020-03-27 | 公開日 | 2020-05-13 | 最終更新日 | 2020-06-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
|
|
6N10
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n10 by Molmil](/molmil-images/mine/6n10) | Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP | 分子名称: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ... | 著者 | Noel, J.P, Thomas, S.T, Louie, G.V. | 登録日 | 2018-11-07 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
|
|
6N1A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n1a by Molmil](/molmil-images/mine/6n1a) | Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii | 分子名称: | CALCIUM ION, Carbohydrate-binding protein, GLYCEROL, ... | 著者 | Sim, L, Rahfeld, P, Withers, S.G. | 登録日 | 2018-11-08 | 公開日 | 2019-06-12 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nat Microbiol, 4, 2019
|
|
2AIB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2aib by Molmil](/molmil-images/mine/2aib) | beta-cinnamomin in complex with ergosterol | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-elicitin cinnamomin, ERGOSTEROL, ... | 著者 | Rodrigues, M.L, Archer, M, Martel, P, Miranda, S, Thomaz, M, Enguita, F.J, Baptista, R.P, Melo, E.P, Sousa, N, Cravador, A, Carrondo, M.A. | 登録日 | 2005-07-29 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Crystal structures of the free and sterol-bound forms of beta-cinnamomin Biochim.Biophys.Acta, 1764, 2006
|
|
4TSH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tsh by Molmil](/molmil-images/mine/4tsh) | A Novel Protein Fold Forms an Intramolecular Lock to Stabilize the Tertiary Structure of Streptococcus mutans Adhesin P1 | 分子名称: | CALCIUM ION, MAGNESIUM ION, Surface protein adhesin | 著者 | Heim, K.P, Kailasan, S, McKenna, R, Brady, L.J. | 登録日 | 2014-06-18 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6CG4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cg4 by Molmil](/molmil-images/mine/6cg4) | |
6FW7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fw7 by Molmil](/molmil-images/mine/6fw7) | Crystal structure of L-tryptophan oxidase VioA from Chromobacterium violaceum in complex with 4-Fluoro-L-Tryptophan | 分子名称: | 4-FLUOROTRYPTOPHANE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent L-tryptophan oxidase VioA, ... | 著者 | Lai, H.E, Morgan, M, Moore, S, Freemont, P. | 登録日 | 2018-03-05 | 公開日 | 2019-02-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A GenoChemetic strategy for derivatization of the violacein natural product scaffold Biorxiv, 2019
|
|
2JYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jyu by Molmil](/molmil-images/mine/2jyu) | Human Granulin C, isomer 2 | 分子名称: | Granulin-5 | 著者 | Tolkatchev, D, Wang, P, Chen, Z, Xu, P, Ni, F. | 登録日 | 2007-12-19 | 公開日 | 2008-04-22 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities. Protein Sci., 17, 2008
|
|
6O24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o24 by Molmil](/molmil-images/mine/6o24) | Crystal structure of 4498 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain | 分子名称: | 1,2-ETHANEDIOL, 4498 Fab heavy chain, 4498 Kappa light chain, ... | 著者 | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | 登録日 | 2019-02-22 | 公開日 | 2020-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nat. Med., 26, 2020
|
|
6WZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wz6 by Molmil](/molmil-images/mine/6wz6) | Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Glu at pH 5. Covalent acyl-enzyme intermediate | 分子名称: | 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutaminase-asparaginase | 著者 | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | 登録日 | 2020-05-13 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria. Sci Rep, 10, 2020
|
|
1U01
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u01 by Molmil](/molmil-images/mine/1u01) | High resolution NMR structure of 5-d(GCGT*GCG)-3/5-d(CGCACGC)-3 (T*represents a cyclohexenyl nucleotide) | 分子名称: | 5'-D(*CP*GP*CP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*(XTR)P*GP*CP*G)-3' | 著者 | Nauwelaerts, K, Lescrinier, E, Sclep, G, Herdewijn, P. | 登録日 | 2004-07-12 | 公開日 | 2005-05-31 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides. Nucleic Acids Res., 33, 2005
|
|
6G7E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g7e by Molmil](/molmil-images/mine/6g7e) | |
3DLE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dle by Molmil](/molmil-images/mine/3dle) | |
4KKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kks by Molmil](/molmil-images/mine/4kks) | Crystal Structure of BesA (C2 form) | 分子名称: | Membrane fusion protein, PHOSPHATE ION | 著者 | Greene, N.P, Hinchliffe, P, Crow, A, Ababou, A, Hughes, C, Koronakis, V. | 登録日 | 2013-05-06 | 公開日 | 2013-07-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi. Febs Lett., 587, 2013
|
|
3R2M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r2m by Molmil](/molmil-images/mine/3r2m) | 1.8A resolution structure of Doubly Soaked FtnA from Pseudomonas aeruginosa (pH 7.5) | 分子名称: | Bacterioferritin, FE (III) ION, SODIUM ION | 著者 | Lovell, S.W, Battaile, K.P, Yao, H, Jepkorir, G, Nama, P.V, Weeratunga, S, Rivera, M. | 登録日 | 2011-03-14 | 公開日 | 2011-05-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Two distinct ferritin-like molecules in Pseudomonas aeruginosa: the product of the bfrA gene is a bacterial ferritin (FtnA) and not a bacterioferritin (Bfr). Biochemistry, 50, 2011
|
|