8UWB

Crystal structure of PP2A PPP2R1A-PPP2CA-PPP2R5E phosphatase.

Summary for 8UWB

• Entry DOI: 10.2210/pdb8uwb/pdb
• Descriptor: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... (4 entities in total)
• Functional Keywords: pp2a, protein phosphatase, serine/threonine-protein phosphatase 2a, b56epsilon, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 322604.72

Authors

Wachter, F.,Nowak, R.P.,Fischer, E.S. (deposition date: 2023-11-06, release date: 2024-04-17)

• Primary citation: Wachter, F.,Nowak, R.P.,Ficarro, S.,Marto, J.,Fischer, E.S.; Structural characterization of methylation-independent PP2A assembly guides Alphafold2Multimer prediction of family-wide PP2A complexes.; J.Biol.Chem., :107268-107268, 2024; PubMed: 38582449; DOI: 10.1016/j.jbc.2024.107268

Experimental method

X-RAY DIFFRACTION (3.15 Å)