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PDB: 45955 件

6FCL
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Crystal Structure of Human APRT wild type in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase
著者Nioche, P, Huyet, J, Ozeir, M.
登録日2017-12-20
公開日2018-08-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
4QF1
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Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
著者Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2014-05-19
公開日2015-02-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
8DCX
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PI 3-kinase alpha with nanobody 3-159
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
著者Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W.
登録日2022-06-17
公開日2022-09-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
6FD6
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Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 30 days post crystallization (with AMP and PPi products fully generated)
分子名称: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, MAGNESIUM ION, ...
著者Nioche, P, Huyet, J, Ozeir, M.
登録日2017-12-21
公開日2018-08-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
5O7B
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CRYSTAL STRUCTURE OF THE SLR0328 TYROSINE PHOSPHATASE WZB FROM SYNECHOCYSTIS SP. PCC 6803
分子名称: Putative low molecular weight protein-tyrosine-phosphatase slr0328
著者Leite, J.P, Gales, L.
登録日2017-06-08
公開日2018-06-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.281 Å)
主引用文献The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803.
Microbiologyopen, 2019
3F1J
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BU of 3f1j by Molmil
Crystal structure of the Borna disease virus matrix protein (BDV-M) reveals RNA binding properties
分子名称: CYTIDINE-5'-MONOPHOSPHATE, Matrix protein, SULFATE ION
著者Neumann, P, Lieber, D, Meyer, S, Dautel, P, Kerth, A, Kraus, I, Garten, W, Stubbs, M.T.
登録日2008-10-28
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the Borna disease virus matrix protein (BDV-M) reveals ssRNA binding properties
Proc.Natl.Acad.Sci.USA, 106, 2009
6UOI
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Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with malonate
分子名称: FE (III) ION, FE3-S4 CLUSTER, Fumarate hydratase 2, ...
著者Feliciano, P.R, Drennan, C.L.
登録日2019-10-15
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase fromLeishmania major.
Biochemistry, 58, 2019
6ACS
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poly-cis-prenyltransferase
分子名称: CITRIC ACID, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), GLYCEROL, ...
著者Ko, T.-P, Chen, Y.
登録日2018-07-27
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure of undecaprenyl pyrophosphate synthase from Acinetobacter baumannii
Acta Crystallogr F Struct Biol Commun, 74, 2018
8SFX
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High Affinity nanobodies against GFP
分子名称: D-MALATE, GLYCEROL, Green fluorescent protein, ...
著者Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C.
登録日2023-04-11
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献High Affinity nanobodies against GFP
To Be Published
6EV4
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Structure of wild type A. niger Fdc1 purified in the dark with prFMN in the iminium form
分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Ferulic acid decarboxylase 1, MANGANESE (II) ION, ...
著者Bailey, S.S, David, L, Payne, K.A.P.
登録日2017-11-01
公開日2017-12-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis.
J. Biol. Chem., 293, 2018
6UPQ
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BU of 6upq by Molmil
Crystal Structure of GTPase Domain of Human Septin 2 / Septin 11 Heterocomplex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Leonardo, D.A, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C.
登録日2019-10-18
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Molecular Recognition at Septin Interfaces: The Switches Hold the Key.
J.Mol.Biol., 432, 2020
6M69
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Crystal structure of Mycobacterium smegmatis MutT1 in complex with GMPPCP (GDP)
分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Hydrolase, ...
著者Raj, P, Karthik, S, Arif, S.M, Varshney, U, Vijayan, M.
登録日2020-03-13
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1.
Acta Crystallogr D Struct Biol, 76, 2020
8D1M
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BU of 8d1m by Molmil
hBest1 Ca2+-unbound closed state
分子名称: Bestrophin-1
著者Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y.
登録日2022-05-27
公開日2022-07-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
8SG3
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BU of 8sg3 by Molmil
High Affinity nanobodies against GFP
分子名称: Green fluorescent protein, LaG41
著者Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C.
登録日2023-04-11
公開日2024-05-22
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献High Affinity nanobodies against GFP
To Be Published
6URJ
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BU of 6urj by Molmil
Barrier-to-autointegration factor soaked in Acetone: 1 of 14 in MSCS set
分子名称: Barrier-to-autointegration factor, ETHANOL
著者Agarwal, S, Smith, M, De La Rosa, I, Kliment, A.V, Swartz, P, Segura-Totten, M, Mattos, C.
登録日2019-10-23
公開日2020-10-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor.
Acta Crystallogr D Struct Biol, 76, 2020
5O7H
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BU of 5o7h by Molmil
Structure of the Cascade-I-Fv complex from Shewanella putrefaciens
分子名称: CRISPR-associated protein, Csy4 family, Cas5fv, ...
著者Pausch, P, Altegoer, F, Bange, G.
登録日2017-06-08
公開日2017-08-16
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell, 67, 2017
5OLL
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BU of 5oll by Molmil
Crystal structure of gurmarin, a sweet taste suppressing polypeptide
分子名称: Gurmarin, NICKEL (II) ION
著者Sigoillot, M, Neiers, F, Legrand, P, Roblin, P, Briand, L.
登録日2017-07-28
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Crystal Structure of Gurmarin, a Sweet Taste-Suppressing Protein: Identification of the Amino Acid Residues Essential for Inhibition.
Chem. Senses, 43, 2018
6USB
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BU of 6usb by Molmil
Barrier-to-autointegration factor soaked in urea: 1 of 14 in MSCS set
分子名称: Barrier-to-autointegration factor, ETHANOL
著者Agarwal, S, Smith, M, De La Rosa, I, Kliment, A.V, Swartz, P, Segura-Totten, M, Mattos, C.
登録日2019-10-25
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor.
Acta Crystallogr D Struct Biol, 76, 2020
6MB5
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AAC-IIIb binary with NEOMYCIN
分子名称: Aac(3)-IIIb protein, NEOMYCIN
著者Cuneo, M.J, Kumar, P.
登録日2018-08-29
公開日2018-11-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
J. Med. Chem., 61, 2018
4L1L
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Rat PKC C2 domain bound to CD
分子名称: CADMIUM ION, Protein kinase C alpha type, SULFATE ION
著者Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I.
登録日2013-06-03
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional.
J.Am.Chem.Soc., 135, 2013
6MB7
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Binary (paromomycin) structure of AAC-IIIb
分子名称: Aac(3)-IIIb protein, PAROMOMYCIN
著者Cuneo, M.J, Kumar, P.
登録日2018-08-29
公開日2018-11-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
J. Med. Chem., 61, 2018
3IGO
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BU of 3igo by Molmil
Crystal structure of Cryptosporidium parvum CDPK1, cgd3_920
分子名称: CALCIUM ION, Calmodulin-domain protein kinase 1, GLYCEROL, ...
著者Wernimont, A.K, Artz, J.D, Finnerty, P, Amani, M, Allali-Hassanali, A, Vedadi, M, Tempel, W, MacKenzie, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC)
登録日2009-07-28
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.
Nat.Struct.Mol.Biol., 17, 2010
3FDN
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Structure-based drug design of novel Aurora kinase A inhibitors: Structure basis for potency and specificity
分子名称: N-[3-(acetylamino)phenyl]-5-{(2E)-2-[(4-methoxyphenyl)methylidene]hydrazino}-3-methyl-1H-pyrazole-4-carboxamide, Serine/threonine-protein kinase 6
著者Leou, J.S, Wu, J.S, Coumar, M.S, Shukla, P, Hsieh, H.P, Wu, S.Y.
登録日2008-11-26
公開日2009-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity
J.Med.Chem., 52, 2009
6MEE
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Crystal structure of broadly neutralizing antibody HEPC74
分子名称: antibody HEPC74 Heavy Chain, antibody HEPC74 Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2018-09-06
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
6EV8
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Structure of E277Q A. niger Fdc1 with prFMN in the hydroxylated form
分子名称: Ferulic acid decarboxylase 1, MANGANESE (II) ION, POTASSIUM ION, ...
著者Bailey, S.S, David, L, Payne, K.A.P.
登録日2017-11-01
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis.
J. Biol. Chem., 293, 2018

224004

件を2024-08-21に公開中

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