8JI8
| Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ... | 著者 | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | 登録日 | 2023-05-26 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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1P6F
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6EC8
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6O6Q
| Crystal structure of Cka1p, a casein kinase 2 alpha ortholog from Candida albicans | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Casein kinase 2 catalytic subunit, ... | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-03-07 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of Cka1p, a casein kinase 2 alpha ortholog from Candida albicans To Be Published
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3VZC
| Crystal structure of Sphingosine Kinase 1 with inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino}phenol, Sphingosine kinase 1 | 著者 | Min, X, Walker, N.P, Wang, Z. | 登録日 | 2012-10-11 | 公開日 | 2013-05-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis of sphingosine kinase 1 substrate recognition and catalysis. Structure, 21, 2013
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3SVF
| Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand | 分子名称: | (4S)-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-(2-hydroxyethoxy)-3-methyl-3,4-dihydroquinazolin-2(1H)-one, Bromodomain-containing protein 4 | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-07-12 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | 主引用文献 | Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand TO BE PUBLISHED
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1OTV
| PqqC, Pyrroloquinolinquinone Synthase C | 分子名称: | Coenzyme PQQ synthesis protein C | 著者 | Magnusson, O.T, Toyama, H, Saeki, M, Rojas, A, Reed, J.C, Adachi, O, Klinman, J.P, SChwarzenbacher, R. | 登録日 | 2003-03-23 | 公開日 | 2004-05-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Quinone Biogenesis: Structure and Mechanism of PqqC, the Final Catalyst in the Production of Pyrroloquinoline Quinone. Proc.Natl.Acad.Sci.USA, 101, 2004
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6YWO
| CutA in complex with A3 RNA | 分子名称: | CHLORIDE ION, CutA, MAGNESIUM ION, ... | 著者 | Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M. | 登録日 | 2020-04-29 | 公開日 | 2020-08-05 | 最終更新日 | 2020-09-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine. Nucleic Acids Res., 48, 2020
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6RTV
| Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-glucuronoyl methylesterase, ... | 著者 | Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S. | 登録日 | 2019-05-27 | 公開日 | 2020-03-18 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | The structural basis of fungal glucuronoyl esterase activity on natural substrates. Nat Commun, 11, 2020
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7U1Z
| Crystal structure of the DRBD and CROPs of TcdA | 分子名称: | SULFATE ION, Toxin A | 著者 | Baohua, C, Peng, C, Kay, P, Rongsheng, J. | 登録日 | 2022-02-22 | 公開日 | 2022-03-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | Structure and conformational dynamics of Clostridioides difficile toxin A. Life Sci Alliance, 5, 2022
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32C2
| STRUCTURE OF AN ACTIVITY SUPPRESSING FAB FRAGMENT TO CYTOCHROME P450 AROMATASE | 分子名称: | IGG1 ANTIBODY 32C2 | 著者 | Sawicki, M.W, Ng, P.C, Burkhart, B, Pletnev, V, Higashiyama, T, Osawa, Y, Ghosh, D. | 登録日 | 1999-04-21 | 公開日 | 2000-04-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of an activity suppressing Fab fragment to cytochrome P450 aromatase: insights into the antibody-antigen interactions. Mol.Immunol., 36, 1999
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3VZO
| Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose | 分子名称: | Endo-1,4-beta-xylanase, SULFATE ION, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | 登録日 | 2012-10-15 | 公開日 | 2013-05-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
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6Z12
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3VZK
| Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant | 分子名称: | Endo-1,4-beta-xylanase, SULFATE ION | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | 登録日 | 2012-10-14 | 公開日 | 2013-05-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
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5M4Q
| Crystal Structure of Wild-Type Human Prolidase with Mn ions and Pro ligand | 分子名称: | GLYCEROL, HYDROXIDE ION, MANGANESE (II) ION, ... | 著者 | Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. | 登録日 | 2016-10-18 | 公開日 | 2017-07-12 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Substrate specificity and reaction mechanism of human prolidase. FEBS J., 284, 2017
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2NMM
| Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409 | 分子名称: | 14 kDa phosphohistidine phosphatase, SULFATE ION | 著者 | Kuzin, A.P, Abashidze, M, Forouhar, F, Seetharaman, J, Kent, C, Fang, Y, Cunningham, K, Conover, K, Ma, L.C, Xiao, R, Acton, T, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-10-22 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409 To be Published
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2NMZ
| Crystal structure analysis of HIV-1 protease mutant V82A with a inhibitor saquinavir | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, PROTEASE, SULFATE ION | 著者 | Tie, Y, Kovalevsky, A.Y, Boross, P, Wang, Y.F, Ghosh, A.K, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2006-10-23 | 公開日 | 2007-03-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir. Proteins, 67, 2007
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6EIC
| Crystal structure of Rv0183, a Monoglyceride Lipase from Mycobacterium Tuberculosis | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Mycobacterium Tuberculosis Monoglyceride Lipase, NITRATE ION, ... | 著者 | Aschauer, P, Pavkov-Keller, T, Oberer, M. | 登録日 | 2017-09-19 | 公開日 | 2018-06-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition. Sci Rep, 8, 2018
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6OBT
| Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases | 分子名称: | Borrelidin polyketide synthase, type I | 著者 | McAndrew, R.P, Barajas, J.F, Pereira, J.H, Keasling, J.D, Adams, P.D. | 登録日 | 2019-03-21 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases. J Ind Microbiol Biotechnol., 46, 2019
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1OZ7
| Crystal structure of Echicetin from the venom of Indian saw-scaled viper (Echis carinatus) at 2.4 resolution | 分子名称: | echicetin A-chain, echicetin B-chain | 著者 | Jasti, J, Paramasivam, M, Srinivasan, A, Singh, T.P. | 登録日 | 2003-04-08 | 公開日 | 2003-12-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of echicetin from Echis carinatus (Indian saw-scaled viper) at 2.4A resolution. J.Mol.Biol., 335, 2004
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6RWI
| Fragment AZ-002 binding at the p53pT387/14-3-3 sigma interface | 分子名称: | 14-3-3 protein sigma, 5-phenylthiophene-2-carboximidamide, CALCIUM ION, ... | 著者 | Leysen, S, Guillory, X, Wolter, M, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C. | 登録日 | 2019-06-05 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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1OZL
| Crystal Structures of the Ferric, Ferrous, and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications | 分子名称: | Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L. | 登録日 | 2003-04-09 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications J.Mol.Biol., 330, 2003
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1OZW
| Crystal Structures of the Ferric, Ferrous and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications | 分子名称: | Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L. | 登録日 | 2003-04-09 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications J.Mol.Biol., 330, 2003
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2NNK
| Crystal structure analysis of HIV-1 protease mutant I84V with a inhibitor saquinavir | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETIC ACID, CHLORIDE ION, ... | 著者 | Tie, Y, Kovalevsky, A.Y, Boross, P, Wang, Y.F, Ghosh, A.K, Tozser, J, Harrison, R.W, Weber, I.T. | 登録日 | 2006-10-24 | 公開日 | 2007-03-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir. Proteins, 67, 2007
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7TYY
| Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... | 著者 | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | 登録日 | 2022-02-14 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A structural basis for amylin receptor phenotype. Science, 375, 2022
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