3F8F
| Crystal structure of multidrug binding transcriptional regulator LmrR complexed with Daunomycin | 分子名称: | DAUNOMYCIN, Transcriptional regulator, PadR-like family | 著者 | Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H. | 登録日 | 2008-11-12 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. Embo J., 28, 2009
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6T1N
| Crystal structure of MLLT1 (ENL) YEATS domain in complexed with benzimidazole-amide derivative 5 | 分子名称: | 1,2-ETHANEDIOL, 4-chloranyl-~{N}-[2-(piperidin-1-ylmethyl)-3~{H}-benzimidazol-5-yl]benzamide, Protein ENL | 著者 | Chaikuad, A, Heidenreich, D, Moustakim, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Fedorov, O, Brennan, P.E, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2019-10-04 | 公開日 | 2019-11-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1. Acs Med.Chem.Lett., 10, 2019
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6TIK
| Hepatitis B virus core shell--virus-like particle with NadA epitope | 分子名称: | Capsid protein,Putative adhesin/invasin,Capsid protein,Factor H-binding protein | 著者 | Roseman, A.M, Colllins, R.F, Derrick, J.P. | 登録日 | 2019-11-22 | 公開日 | 2020-04-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | An assessment of the use of Hepatitis B Virus core protein virus-like particles to display heterologous antigens from Neisseria meningitidis. Vaccine, 38, 2020
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3FH3
| Crystal structure of a putative ECF-type sigma factor negative effector from Bacillus anthracis str. Sterne | 分子名称: | NICKEL (II) ION, putative ECF-type sigma factor negative effector | 著者 | Nocek, B, Kim, Y, Joachimiak, G, Du, J, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-12-08 | 公開日 | 2009-01-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Crystal structure of a putative ECF-type sigma factor negative effector from Bacillus anthracis str. Sterne To be Published
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6DWG
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4MSI
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4N72
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4N9M
| Joint neutron/x-ray structure of urate oxidase in complex with 8-hydroxyxanthine | 分子名称: | 8-hydroxy-3,9-dihydro-1H-purine-2,6-dione, CHLORIDE ION, SODIUM ION, ... | 著者 | Oksanen, E, Blakeley, M.P, Budayova-Spano, M. | 登録日 | 2013-10-21 | 公開日 | 2014-02-05 | 最終更新日 | 2018-06-13 | 実験手法 | NEUTRON DIFFRACTION (2.023 Å), X-RAY DIFFRACTION | 主引用文献 | The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation. Plos One, 9, 2014
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3FOL
| Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFERI | 分子名称: | 8 residue synthetic peptide, Beta-2-microglobulin, MHC | 著者 | Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P. | 登録日 | 2008-12-30 | 公開日 | 2010-01-12 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect Int.Immunol., 22, 2010
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3FOT
| Structural and Functional Characterization of TRI3 Trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides | 分子名称: | 15-O-acetyltransferase, GLYCEROL, SULFATE ION | 著者 | Garvey, G.S, Rayment, I, McCormick, S.P, Alexander, N.J. | 登録日 | 2009-01-01 | 公開日 | 2009-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and functional characterization of TRI3 trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides Protein Sci., 18, 2009
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3FPF
| Crystal Structure of MtNAS in complex with MTA and tNA | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, BROMIDE ION, N-[(3S)-3-{[(3S)-3-amino-3-carboxypropyl]amino}-3-carboxypropyl]-L-glutamic acid, ... | 著者 | Dreyfus, C, Pignol, D, Arnoux, P. | 登録日 | 2009-01-05 | 公開日 | 2009-10-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Crystallographic snapshots of iterative substrate translocations during nicotianamine synthesis in Archaea Proc.Natl.Acad.Sci.USA, 106, 2009
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6DQH
| Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif | 分子名称: | Beta-lactamase, PHOSPHATE ION, ZINC ION | 著者 | Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G. | 登録日 | 2018-06-11 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.104 Å) | 主引用文献 | Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse Protein Cell, 2020
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4NFF
| Human kallikrein-related peptidase 2 in complex with PPACK | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2 | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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3F7L
| X-ray Crystal Structure of Alvinella pompejana Cu,Zn Superoxide Dismutase | 分子名称: | ACETIC ACID, COPPER (I) ION, COPPER (II) ION, ... | 著者 | Shin, D.S, DiDonato, M, Barondeau, D.P, Getzoff, E.D, Tainer, J.A. | 登録日 | 2008-11-09 | 公開日 | 2009-02-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | 主引用文献 | Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis. J.Mol.Biol., 385, 2009
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3FE2
| Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX5, ... | 著者 | Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-11-27 | 公開日 | 2008-12-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Comparative Structural Analysis of Human DEAD-Box RNA Helicases Plos One, 5, 2010
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3FGU
| Catalytic complex of Human Glucokinase | 分子名称: | Glucokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Petit, P, Lagarde, A, Boutin, J.A, Ferry, G, Vuillard, L. | 登録日 | 2008-12-08 | 公開日 | 2009-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The active conformation of human glucokinase is not altered by allosteric activators Acta Crystallogr.,Sect.D, 67, 2011
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4NL4
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6T77
| Crystal structure of Klebsiella pneumoniae FabG(NADPH-dependent) NADP-complex at 1.75 A resolution | 分子名称: | 3-oxoacyl-ACP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Vella, P, Schnell, R, Lindqvist, Y, Schneider, G. | 登録日 | 2019-10-21 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens. Bioorg.Med.Chem., 30, 2021
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3FHN
| Structure of Tip20p | 分子名称: | Protein transport protein TIP20 | 著者 | Tripathi, A, Ren, Y, Jeffrey, P.D, Hughson, F.M. | 登録日 | 2008-12-09 | 公開日 | 2009-01-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat.Struct.Mol.Biol., 16, 2009
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6D9H
| Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist | 分子名称: | ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Draper-Joyce, C.J, Khoshouei, M, Thal, D.M, Liang, Y.-L, Nguyen, A.T.N, Furness, S.G.B, Venugopal, H, Baltos, J, Plitzko, J.M, Danev, R, Baumeister, W, May, L.T, Wootten, D, Sexton, P, Glukhova, A, Christopoulos, A. | 登録日 | 2018-04-29 | 公開日 | 2018-06-20 | 最終更新日 | 2018-07-11 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the adenosine-bound human adenosine A1receptor-Gicomplex. Nature, 558, 2018
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3FKC
| Crystal Structure of Human Zinc finger and BTB domain containing 33 | 分子名称: | Transcriptional regulator Kaiso | 著者 | Filippakopoulos, P, Bullock, A, Keates, T, Burgess-Brown, N, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-16 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Human Zinc finger and BTB domain containing 33 To be Published
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6DQ2
| Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif mutant S60 | 分子名称: | Beta-lactamase, PHOSPHATE ION | 著者 | Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G. | 登録日 | 2018-06-10 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.158 Å) | 主引用文献 | Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse Protein Cell, 2020
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3FM7
| Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain | 分子名称: | Dynein intermediate chain, cytosolic, Dynein light chain 1, ... | 著者 | Hall, J.D, Karplus, P.A, Barbar, E.J. | 登録日 | 2008-12-19 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Multivalency in the assembly of intrinsically disordered Dynein intermediate chain. J.Biol.Chem., 284, 2009
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3FMD
| Crystal Structure of Human Haspin with an Isoquinoline ligand | 分子名称: | 1,2-ETHANEDIOL, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, NICKEL (II) ION, ... | 著者 | Filippakopoulos, P, Eswaran, J, Keates, T, Burgess-Brown, N, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-21 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Haspin with an Isoquinoline ligand To be Published
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3FPH
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