Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 46375 件

3I9A
DownloadVisualize
BU of 3i9a by Molmil
Crystal structure of human transthyretin variant A25T - #1
分子名称: TRIETHYLENE GLYCOL, Transthyretin
著者Palmieri, L.C, Freire, J.B.B, Palhano, F.L, Azevedo, E.P.C, Foguel, D, Lima, L.M.T.R.
登録日2009-07-10
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of human transthyretin variant A25T - #1
To be Published
6B1I
DownloadVisualize
BU of 6b1i by Molmil
Disrupted hydrogen bond network impairs ATPase activity in an Hsc70 cysteine mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock protein family A (Hsp70) member 8, ...
著者O'Donnell, J.P.
登録日2017-09-18
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Disrupted Hydrogen-Bond Network and Impaired ATPase Activity in an Hsc70 Cysteine Mutant.
Biochemistry, 57, 2018
6ULR
DownloadVisualize
BU of 6ulr by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, HLA class I antigen, ...
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
3IU1
DownloadVisualize
BU of 3iu1 by Molmil
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA
分子名称: Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA
著者Qiu, W, Hutchinson, A, Wernimont, A, Lin, Y.-H, Kania, A, Ravichandran, M, Kozieradzki, I, Cossar, D, Schapira, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Wyatt, P.G, Ferguson, M.A.J, Frearson, J.A, Brand, S.Y, Robinson, D.A, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
登録日2009-08-29
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA
To be Published
6TVC
DownloadVisualize
BU of 6tvc by Molmil
Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Haemagglutinin HA1, Haemagglutinin HA2
著者Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
登録日2020-01-09
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals.
Cell Host Microbe, 28, 2020
6HWM
DownloadVisualize
BU of 6hwm by Molmil
Structure of Thermus thermophilus ClpP in complex with bortezomib
分子名称: ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE
著者Felix, J, Schanda, P, Fraga, H, Morlot, C.
登録日2018-10-12
公開日2019-09-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors.
Sci Adv, 5, 2019
1LUR
DownloadVisualize
BU of 1lur by Molmil
Crystal Structure of the GalM/aldose Epimerase Homologue from C. elegans, Northeast Structural Genomics Target WR66
分子名称: SULFATE ION, aldose 1-epimerase
著者Keller, J.P, Xiao, R, MacDonald, L, Shen, J, Acton, T, Montelione, G, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2002-05-23
公開日2003-07-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the GalM/aldose Epimerase Homologue from C. elegans, Northeast Structural Genomics Target WR66
TO BE PUBLISHED
1CEO
DownloadVisualize
BU of 1ceo by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN
分子名称: CELLULASE CELC
著者Dominguez, R, Alzari, P.M.
登録日1995-12-04
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
1LXC
DownloadVisualize
BU of 1lxc by Molmil
Crystal Structure of E. Coli Enoyl Reductase-NAD+ with a Bound Acrylamide Inhibitor
分子名称: 3-(6-AMINOPYRIDIN-3-YL)-N-METHYL-N-[(1-METHYL-1H-INDOL-2-YL)METHYL]ACRYLAMIDE, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Miller, W.H, Seefeld, M.A, Newlander, K.A, Uzinskas, I.N, Burgess, W.J, Heerding, D.A, Yuan, C.C.K, Head, M.S, Payne, D.J, Rittenhouse, S.F, Moore, T.D, Pearson, S.C, Dewolf, V, Berry, W.E, Keller, P.M, Polizzi, B.J, Qiu, X, Janson, C.A, Huffman, W.F.
登録日2002-06-05
公開日2002-09-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
J.Med.Chem., 45, 2002
1D8B
DownloadVisualize
BU of 1d8b by Molmil
NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE
分子名称: SGS1 RECQ HELICASE
著者Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M.
登録日1999-10-21
公開日2000-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
1CIT
DownloadVisualize
BU of 1cit by Molmil
DNA-BINDING MECHANISM OF THE MONOMERIC ORPHAN NUCLEAR RECEPTOR NGFI-B
分子名称: DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), PROTEIN (ORPHAN NUCLEAR RECEPTOR NGFI-B), ...
著者Meinke, G, Sigler, P.B.
登録日1999-04-05
公開日1999-05-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B.
Nat.Struct.Biol., 6, 1999
1CEN
DownloadVisualize
BU of 1cen by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN COMPLEXED WITH CELLOHEXAOSE
分子名称: CELLULASE CELC, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Dominguez, R, Alzari, P.M.
登録日1995-12-04
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
1LXY
DownloadVisualize
BU of 1lxy by Molmil
Crystal Structure of Arginine Deiminase covalently linked with L-citrulline
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arginine Deiminase, CITRULLINE
著者Das, K, Buttler, G.H, Kwiatkowski, V, Yadav, P, Arnold, E.
登録日2002-06-06
公開日2004-01-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism
Structure, 12, 2004
4QKZ
DownloadVisualize
BU of 4qkz by Molmil
X-ray structure of the catalytic domain of MMP-8 with the inhibitor ML115
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Neutrophil collagenase, ...
著者Pochetti, G, Montanari, R, Capelli, D, Tortorella, P.
登録日2014-06-10
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy.
Pharmaceuticals, 13, 2020
4N1H
DownloadVisualize
BU of 4n1h by Molmil
Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis
分子名称: Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N
著者Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
登録日2013-10-04
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
3IPT
DownloadVisualize
BU of 3ipt by Molmil
Crystal Structure of Ketosteroid Isomerase Y16S/D40N from Pseudomonas putida with Bound Equilenin
分子名称: EQUILENIN, Steroid Delta-isomerase
著者Fenn, T.D, Sigala, P.A, Herschlag, D.
登録日2009-08-18
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.632 Å)
主引用文献Dissecting the paradoxical effects of hydrogen bond mutations in the ketosteroid isomerase oxyanion hole.
Proc.Natl.Acad.Sci.USA, 107, 2010
4QMA
DownloadVisualize
BU of 4qma by Molmil
Crystal Structure of a Putative Cysteine Dioxygnase From Ralstonia eutropha: An Alternative Modeling of 2GM6 from JCSG Target 361076
分子名称: 1,2-ETHANEDIOL, Cysteine dioxygenase type I, FE (III) ION, ...
著者Hartman, S.H, Driggers, C.M, Karplus, P.A, Joint Center for Structural Genomics (JCSG)
登録日2014-06-15
公開日2014-11-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of Arg- and Gln-type bacterial cysteine dioxygenase homologs.
Protein Sci., 24, 2015
4QOK
DownloadVisualize
BU of 4qok by Molmil
Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
登録日2014-06-20
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.
Eur.J.Immunol., 45, 2015
6ZJC
DownloadVisualize
BU of 6zjc by Molmil
Crystal structure of Equus ferus caballus glutathione transferase A3-3 in complex with glutathione and triethyltin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLUTATHIONE, Glutathione S-transferase, ...
著者Skerlova, J, Ismail, A, Lindstrom, H, Sjodin, B, Mannervik, B, Stenmark, P.
登録日2020-06-28
公開日2020-11-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants.
Environ Pollut, 268, 2021
6LCM
DownloadVisualize
BU of 6lcm by Molmil
Crystal structure of chloroplast resolvase ZmMOC1 with the magic triangle I3C
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, ZmMoc1
著者Yan, J.J, Hong, S.X, Guan, Z.Y, Yin, P.
登録日2019-11-19
公開日2020-04-08
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1.
Nat Commun, 11, 2020
1M9F
DownloadVisualize
BU of 1m9f by Molmil
X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,A88M Complex.
分子名称: Cyclophilin A, HIV-1 Capsid
著者Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
登録日2002-07-28
公開日2003-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
3ISZ
DownloadVisualize
BU of 3isz by Molmil
Crystal structure of mono-zinc form of succinyl-diaminopimelate desuccinylase from Haemophilus influenzae
分子名称: SULFATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION
著者Nocek, B.P, Gillner, D.M, Holz, R.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-08-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase.
J.Mol.Biol., 397, 2010
6HGS
DownloadVisualize
BU of 6hgs by Molmil
Crystal Structure of Human APRT wild type in complex with GMP
分子名称: Adenine phosphoribosyltransferase, GUANOSINE-5'-MONOPHOSPHATE
著者Nioche, P, Huyet, J, Ozeir, M.
登録日2018-08-23
公開日2019-07-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.
J.Biol.Chem., 294, 2019
1CVY
DownloadVisualize
BU of 1cvy by Molmil
CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYPYPYBETADP)2 BOUND TO CCAGATCTGG
分子名称: 5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', IMIDAZOLE-PYRROLE POLYAMIDE
著者Kielkopf, C.L, Bremer, R.E, White, S, Baird, E.E, Dervan, P.B, Rees, D.C.
登録日1999-08-24
公開日2000-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
3ILS
DownloadVisualize
BU of 3ils by Molmil
The Thioesterase Domain from PksA
分子名称: Aflatoxin biosynthesis polyketide synthase
著者Korman, T.P.
登録日2009-08-07
公開日2010-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis.
Proc.Natl.Acad.Sci.USA, 107, 2010

226262

件を2024-10-16に公開中

PDB statisticsPDBj update infoContact PDBjnumon