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PDB: 46375 件

2WHD
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Barley NADPH-dependent thioredoxin reductase 2
分子名称: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, THIOREDOXIN REDUCTASE
著者Kirkensgaard, K.G, Hagglund, P, Finnie, C, Svensson, B, Henriksen, A.
登録日2009-05-04
公開日2009-09-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Hordeum Vulgare Nadph-Dependent Thioredoxin Reductase 2. Unwinding the Reaction Mechanism.
Acta Crystallogr.,Sect.D, 65, 2009
5WL4
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Crystal structure of chalcone isomerase engineered from ancestral inference (ancR3)
分子名称: Engineered Chalcone Isomerase ancR3, FORMIC ACID
著者Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P.
登録日2017-07-25
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
6P60
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BU of 6p60 by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody A12V163-a.02 in complex with HIV fusion peptide (residue 512-519)
分子名称: Antibody A12V163-a.02 heavy chain, Antibody A12V163-a.02 light chain, HIV fusion peptide residue 512-519
著者Xu, K, Liu, K, Kwong, P.D.
登録日2019-05-31
公開日2020-06-03
実験手法X-RAY DIFFRACTION (2.498 Å)
主引用文献Vaccine-elicited NHP FP-targeting neutralizing antibody A12V163-a.02 in complex with HIV fusion peptide (residue 512-519)
To Be Published
5MDN
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Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis
分子名称: DNA polymerase, MAGNESIUM ION
著者Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M.
登録日2016-11-12
公開日2016-12-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
6S9X
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Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 15c
分子名称: RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-[(4-hydroxyphenyl)methyl]-6-oxidanylidene-2-phenyl-1~{H}-pyrazin-3-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2019-07-15
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity.
Angew.Chem.Int.Ed.Engl., 58, 2019
3OUQ
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BU of 3ouq by Molmil
Structure of N-terminal hexaheme fragment of GSU1996
分子名称: Cytochrome c family protein, HEME C
著者Pokkuluri, P.R, Schiffer, M.
登録日2010-09-15
公開日2010-12-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes.
J.Struct.Biol., 174, 2011
8NSE
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BU of 8nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, NNA COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, CACODYLIC ACID, GLYCEROL, ...
著者Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L.
登録日1999-01-14
公開日2001-11-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
6SA5
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SALSA / DMBT1 / GP340 SRCR domain 8
分子名称: Deleted in malignant brain tumors 1 protein, GLYCEROL, MAGNESIUM ION, ...
著者Reichhardt, M.P, Johnson, S, Loimaranta, V, Lea, S.M.
登録日2019-07-16
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold.
Life Sci Alliance, 3, 2020
5WTU
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BU of 5wtu by Molmil
Crystal structure of DndE G21/24K mutant involved in DNA phosphorothioation
分子名称: DNA sulfur modification protein DndE
著者Yao, P, Liu, Y, Wang, C, Cao, C.
登録日2016-12-14
公開日2018-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of DndE G21/24K mutant involved in DNA phosphorothioation
To Be Published
2X5S
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BU of 2x5s by Molmil
Crystal structure of T. maritima GDP-mannose pyrophosphorylase in apo state.
分子名称: MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE
著者Pelissier, M.C, Lesley, S, Kuhn, P, Bourne, Y.
登録日2010-02-10
公開日2010-06-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Insights Into the Catalytic Mechanism of Bacterial Guanosine-Diphospho-D-Mannose Pyrophosphorylase and its Regulation by Divalent Ions.
J.Biol.Chem., 285, 2010
5WJ7
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Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Xrcc4
分子名称: DNA repair protein XRCC4,Myosin-7
著者Andreas, M.P, Ajay, G, Gellings, J, Rayment, I.
登録日2017-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod.
J. Struct. Biol., 200, 2017
3ORH
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BU of 3orh by Molmil
Human guanidinoacetate N-methyltransferase with SAH
分子名称: Guanidinoacetate N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Dong, A, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2010-09-07
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The crystal structure of human guanidinoacetate N-methyltransferase with SAH
TO BE PUBLISHED
5WKS
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BU of 5wks by Molmil
Crystal structure of chalcone isomerase engineered from ancestral inference complexed with naringenin (ancR1)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Engineered Chalcone Isomerase ancR1, FORMIC ACID, ...
著者Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P.
登録日2017-07-25
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
7X05
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CryoEM structure of chitin synthase 1 from Phytophthora sojae complexed with the nascent chitooligosaccharide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin synthase, MANGANESE (II) ION, ...
著者Chen, W, Cao, P, Gong, Y, Yang, Q.
登録日2022-02-21
公開日2022-09-28
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for directional chitin biosynthesis.
Nature, 610, 2022
5WKZ
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VH1-69 germline antibody predicted from CR6261
分子名称: Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION
著者Lang, S, Lee, P.S.
登録日2017-07-25
公開日2018-08-01
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem
To Be Published
2X16
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Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
分子名称: TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL
著者Salin, M, Kapetaniou, E.G, Vaismaa, M, Lajunen, M, Casteleijn, M.G, Neubauer, P, Salmon, L, Wierenga, R.
登録日2009-12-21
公開日2009-12-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystallographic Binding Studies with an Engineered Monomeric Variant of Triosephosphate Isomerase
Acta Crystallogr.,Sect.D, 66, 2010
6SHW
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BU of 6shw by Molmil
N-terminal domain of Drosophila X Virus VP3
分子名称: SULFATE ION, Structural polyprotein
著者Ferrero, D.S, Garriga, D, Guerra, P, Uson, I, Verdaguer, N.
登録日2019-08-08
公開日2020-11-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and dsRNA-binding activity of the Birnavirus Drosophila X Virus VP3 protein.
J.Virol., 2020
5WL5
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BU of 5wl5 by Molmil
Crystal structure of chalcone isomerase engineered from ancestral inference (ancR5)
分子名称: CHLORIDE ION, Engineered Chalcone Isomerase ancR5, SULFATE ION
著者Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P.
登録日2017-07-25
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.513 Å)
主引用文献Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
5WL7
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Crystal structure of chalcone isomerase engineered from ancestral inference (ancCHI*)
分子名称: CHLORIDE ION, Engineered Chalcone Isomerase ancCHI*
著者Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P.
登録日2017-07-25
公開日2018-05-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
2WOU
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ALK5 IN COMPLEX WITH 4-((4-((2,6-dimethyl-3-pyridyl)oxy)-2-pyridyl) amino)benzenesulfonamide
分子名称: 1,2-ETHANEDIOL, 4-({4-[(2,6-DIMETHYLPYRIDIN-3-YL)OXY]PYRIDIN-2-YL}AMINO)BENZENESULFONAMIDE, TGF-BETA RECEPTOR TYPE-1
著者Debreczeni, J.E, Norman, R.A, Goldberg, F.W, Ward, R.A, Finlay, R, Powell, S.J, Roberts, N.J, Dishington, A.P, Gingell, H.J, Wickson, K.F, Roberts, A.L.
登録日2009-07-28
公開日2009-09-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rapid Generation of a High Quality Lead for Transforming Growth Factor-Beta (Tgf-Beta) Type I Receptor (Alk5).
J.Med.Chem., 52, 2009
6SIN
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BU of 6sin by Molmil
Fragment AZ-020 binding at the p53pT387/14-3-3 sigma interface
分子名称: 14-3-3 protein sigma, Cellular tumor antigen p53, ~{N}-[2-(5-carbamimidoylthiophen-3-yl)phenyl]prop-2-enamide
著者Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Patel, J, Castaldi, P, Ottmann, C.
登録日2019-08-10
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Fragment-based Differential Targeting of PPI Stabilizer Interfaces.
J.Med.Chem., 63, 2020
2WSN
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Structure of Enhanced Cyan Fluorescent Protein at physiological pH
分子名称: GREEN FLUORESCENT PROTEIN
著者Lelimousin, M, Noirclerc-Savoye, M, Lazareno-Saez, C, Paetzold, B, Le Vot, S, Chazal, R, Macheboeuf, P, Field, M.J, Bourgeois, D, Royant, A.
登録日2009-09-08
公開日2009-09-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Intrinsic Dynamics in Ecfp and Cerulean Control Fluorescence Quantum Yield.
Biochemistry, 48, 2009
3P6B
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The crystal structure of CelK CBM4 from Clostridium thermocellum
分子名称: ACETATE ION, CALCIUM ION, Cellulose 1,4-beta-cellobiosidase, ...
著者Alahuhta, P.M, Luo, Y, Lunin, V.V.
登録日2010-10-11
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of CBM4 from Clostridium thermocellum cellulase K.
Acta Crystallogr.,Sect.F, 67, 2011
7X06
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CryoEM structure of chitin synthase 1 from Phytophthora sojae complexed with UDP
分子名称: Chitin synthase, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE
著者Chen, W, Cao, P, Gong, Y, Yang, Q.
登録日2022-02-21
公開日2022-09-28
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for directional chitin biosynthesis.
Nature, 610, 2022
3P48
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Structure of the yeast dUTPase DUT1 in complex with dUMPNPP
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION
著者Petit, P, Singer, A.U, Evdokimova, E, Kudritska, M, Edwards, A.M, Yakunin, A.F, Savchenko, A, Ontario Centre for Structural Proteomics (OCSP)
登録日2010-10-06
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.
Biochem.J., 437, 2011

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