7LNX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lnx by Molmil](/molmil-images/mine/7lnx) | I146A mutant of the isopentenyl phosphate kinase from Candidatus methanomethylophilus alvus | 分子名称: | (2E)-3-methylhept-2-en-1-yl dihydrogen phosphate, (2Z)-3-methylhept-2-en-1-yl trihydrogen diphosphate, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Thomas, L.M, Singh, S, Johnson, B.P. | 登録日 | 2021-02-08 | 公開日 | 2021-12-22 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
|
|
5VJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vj0 by Molmil](/molmil-images/mine/5vj0) | |
5VJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vjs by Molmil](/molmil-images/mine/5vjs) | De Novo Photosynthetic Reaction Center Protein Equipped with Heme B, a synthetic Zn porphyrin, and Zn(II) cations | 分子名称: | CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Reaction Center Maquette, ... | 著者 | Ennist, N.M, Dutton, P.L, Stayrook, S.E, Moser, C.C. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | De novo protein design of photochemical reaction centers. Nat Commun, 13, 2022
|
|
7QU9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qu9 by Molmil](/molmil-images/mine/7qu9) | Structure of aminodeoxychorismate synthase component 1 (PabB) from Bacillus subtilis spizizenii. | 分子名称: | Anthranilate synthase component I family protein, GLYCEROL, TRYPTOPHAN | 著者 | Rooms, L.D, Race, P.R, Back, C.B, Burton, N.B, Willis, C.L, Stach, J.E.M, Duke, P.W, Hawkins, C. | 登録日 | 2022-01-17 | 公開日 | 2023-01-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structure of aminodeoxychorismate synthase component 1 (PabB) from Bacillus subtilis spizizenii. To Be Published
|
|
5VKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vkb by Molmil](/molmil-images/mine/5vkb) | Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and argininamide | 分子名称: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININEAMIDE, ... | 著者 | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | 登録日 | 2017-04-21 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.139 Å) | 主引用文献 | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
|
|
3UUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uub by Molmil](/molmil-images/mine/3uub) | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in solution | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | 登録日 | 2011-11-28 | 公開日 | 2012-05-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
|
|
7QXV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qxv by Molmil](/molmil-images/mine/7qxv) | Crystal Structure of Haem-Binding Protein HemS Mutant F104A F199A, from Yersinia enterocolitica | 分子名称: | DI(HYDROXYETHYL)ETHER, Hemin transport protein | 著者 | Barker, P.D, Keith, A, Brear, P, Wales, D. | 登録日 | 2022-01-27 | 公開日 | 2023-02-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Crystal Structure of Haem-Binding Protein HemS Mutant F104A F199A, from Yersinia enterocolitica To Be Published
|
|
6KCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kcm by Molmil](/molmil-images/mine/6kcm) | Crystal structure of Plasmodium falciparum HPPK-DHPS S436F/A437G/A613S with pterin and p-hydrobenzoate | 分子名称: | 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Chitnumsub, P, Jaruwat, A, Yuthavong, Y. | 登録日 | 2019-06-28 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
|
|
3HA4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ha4 by Molmil](/molmil-images/mine/3ha4) | |
3UM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3um8 by Molmil](/molmil-images/mine/3um8) | Wild-type Plasmodium falciparum DHFR-TS complexed with cycloguanil and NADPH | 分子名称: | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Vanichtanankul, J, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y. | 登録日 | 2011-11-12 | 公開日 | 2012-07-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil. Antimicrob.Agents Chemother., 56, 2012
|
|
5CYO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cyo by Molmil](/molmil-images/mine/5cyo) | High resolution Septin 9 GTPase domain in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-9 | 著者 | Matos, S.S, Leonardo, D.A, Pereira, H.M, Horjales, E, Araujo, A.P.U, Garratt, R.C. | 登録日 | 2015-07-30 | 公開日 | 2016-08-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.0354 Å) | 主引用文献 | A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface Iucrj, 2020
|
|
6KL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kl8 by Molmil](/molmil-images/mine/6kl8) | Crystal structure of Piptidyl t-RNA hydrolase from Acinetobacter baumannii with bound NaCl at the substrate binding site | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase, ... | 著者 | Viswanathan, V, Sharma, P, Singh, P.K, Sharma, S, Singh, T.P. | 登録日 | 2019-07-29 | 公開日 | 2019-08-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of Piptidyl t-RNA hydrolase from Acinetobacter baumannii with bound NaCl at the substrate binding site To Be Published
|
|
3H7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h7h by Molmil](/molmil-images/mine/3h7h) | Crystal structure of the human transcription elongation factor DSIF, hSpt4/hSpt5 (176-273) | 分子名称: | BETA-MERCAPTOETHANOL, Transcription elongation factor SPT4, Transcription elongation factor SPT5, ... | 著者 | Wenzel, S, Wohrl, B.M, Rosch, P, Martins, B.M. | 登録日 | 2009-04-27 | 公開日 | 2009-12-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface Biochem.J., 425, 2010
|
|
3HVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hvt by Molmil](/molmil-images/mine/3hvt) | STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) | 著者 | Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A. | 登録日 | 1994-07-25 | 公開日 | 1994-10-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc.Natl.Acad.Sci.Usa, 91, 1994
|
|
5D2H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d2h by Molmil](/molmil-images/mine/5d2h) | |
2GDR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gdr by Molmil](/molmil-images/mine/2gdr) | Crystal structure of a bacterial glutathione transferase | 分子名称: | GLUTATHIONE, glutathione S-transferase | 著者 | Tocheva, E.I, Fortin, P.D, Eltis, L.D, Murphy, M.E.P. | 登録日 | 2006-03-16 | 公開日 | 2006-08-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of Ternary Complexes of BphK, a Bacterial Glutathione S-Transferase That Reductively Dechlorinates Polychlorinated Biphenyl Metabolites. J.Biol.Chem., 281, 2006
|
|
5VJU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vju by Molmil](/molmil-images/mine/5vju) | De Novo Photosynthetic Reaction Center Protein Variant Equipped with His-Tyr H-bond, Heme B, and Cd(II) ions | 分子名称: | CADMIUM ION, PROTOPORPHYRIN IX CONTAINING FE, Reaction Center Maquette Leu71His variant | 著者 | Ennist, N.M, Stayrook, S.E, Dutton, P.L, Moser, C.C. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | De novo protein design of photochemical reaction centers. Nat Commun, 13, 2022
|
|
5VKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vkl by Molmil](/molmil-images/mine/5vkl) | SPT6 tSH2-RPB1 1476-1500 pS1493 | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 | 著者 | Sdano, M.A, Whitby, F.G, Hill, C.P. | 登録日 | 2017-04-21 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife, 6, 2017
|
|
4OQP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oqp by Molmil](/molmil-images/mine/4oqp) | |
4OIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oit by Molmil](/molmil-images/mine/4oit) | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis | 分子名称: | LysM domain protein, alpha-D-mannopyranose, beta-D-mannopyranose | 著者 | Patra, D, Mishra, P, Surolia, A, Vijayan, M. | 登録日 | 2014-01-20 | 公開日 | 2014-07-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis. Glycobiology, 24, 2014
|
|
4OOA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ooa by Molmil](/molmil-images/mine/4ooa) | CRYSTAL STRUCTURE of NAF1 (MINER1): H114C THE REDOX-ACTIVE 2FE-2S PROTEIN | 分子名称: | CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER | 著者 | Tamir, S, Eisenberg-Domovich, Y, Conlan, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Mittler, R, Jennings, P.A, Livnah, O, Nechushtai, R. | 登録日 | 2014-01-31 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties. Acta Crystallogr.,Sect.D, 70, 2014
|
|
5W2Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w2y by Molmil](/molmil-images/mine/5w2y) | INFLUENZA VIRUS NEURAMINIDASE N9 IN COMPLEX WITH 9-DEOXYGENATED 2,3-DIFLUORO-N-ACETYLNEURAMINIC ACID | 分子名称: | (2R,3R,4R,5R,6R)-5-acetamido-6-[(1R,2R)-1,2-bis(oxidanyl)propyl]-2,3-bis(fluoranyl)-4-oxidanyl-oxane-2-carboxylic acid, (2~{R},3~{R},4~{R},5~{R})-3-acetamido-2-[(1~{R},2~{R})-1,2-bis(oxidanyl)propyl]-5-fluoranyl-4-oxidanyl-2,3,4,5-tetrahydropyran-1-ium-6-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Streltsov, V.A, Mckimm-Breschkin, J, Barrett, S, Pilling, P, Hader, S, Watt, A.G. | 登録日 | 2017-06-07 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural and Functional Analysis of Anti-Influenza Activity of 4-, 7-, 8- and 9-Deoxygenated 2,3-Difluoro- N-acetylneuraminic Acid Derivatives. J. Med. Chem., 61, 2018
|
|
3V09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v09 by Molmil](/molmil-images/mine/3v09) | Crystal structure of Rabbit Serum Albumin | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Majorek, K.A, Porebski, P.J, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2011-12-07 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural and immunologic characterization of bovine, horse, and rabbit serum albumins. Mol.Immunol., 52, 2012
|
|
4O87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o87 by Molmil](/molmil-images/mine/4o87) | Crystal structure of a N-tagged Nuclease | 分子名称: | CITRIC ACID, N-tagged Nuclease, SULFATE ION | 著者 | Chakravarty, A.K, Smith, P, Shuman, S. | 登録日 | 2013-12-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination. Cell Rep, 7, 2014
|
|
4ODA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oda by Molmil](/molmil-images/mine/4oda) | Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminus | 分子名称: | DNA polymerase processivity factor component A20, GLYCEROL, SULFATE ION, ... | 著者 | Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Iseni, F. | 登録日 | 2014-01-10 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit d4 in complex with the a20 N-terminal domain. Plos Pathog., 10, 2014
|
|