1TYK
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![BU of 1tyk by Molmil](/molmil-images/mine/1tyk) | SOLUTION STRUCTURE OF A TOXIN FROM THE TARANTULA, GRAMMOSTOLA SPATULATA, WHICH INHIBITS MECHANOSENSITIVE ION CHANNELS | Descriptor: | Toxin GsMTx-4 | Authors: | Oswald, R.E, Suchyna, T.M, Mcfeeters, R, Gottlieb, P, Sachs, F. | Deposit date: | 2004-07-08 | Release date: | 2004-07-13 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution Structure of Peptide Toxins that Block Mechanosensitive Ion Channels J.Biol.Chem., 277, 2002
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2NBT
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![BU of 2nbt by Molmil](/molmil-images/mine/2nbt) | NEURONAL BUNGAROTOXIN, NMR, 10 STRUCTURES | Descriptor: | NEURONAL BUNGAROTOXIN | Authors: | Oswald, R.E, Sutcliffe, M.J, Bamberger, M, Loring, R.H, Braswell, E, Dobson, C.M. | Deposit date: | 1997-10-29 | Release date: | 1998-03-11 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of neuronal bungarotoxin determined by two-dimensional NMR spectroscopy: calculation of tertiary structure using systematic homologous model building, dynamical simulated annealing, and restrained molecular dynamics. Biochemistry, 31, 1992
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1LUP
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![BU of 1lup by Molmil](/molmil-images/mine/1lup) | Solution structure of a toxin (GsMTx2) from the tarantula, Grammostola spatulata, which inhibits mechanosensitive ion channels | Descriptor: | GsMTx2 | Authors: | Oswald, R.E, Suchyna, T.M, McFeeters, R, Gottlieb, P, Sachs, F. | Deposit date: | 2002-05-23 | Release date: | 2002-08-07 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of peptide toxins that block mechanosensitive ion channels J.Biol.Chem., 277, 2002
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3LSW
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![BU of 3lsw by Molmil](/molmil-images/mine/3lsw) | Aniracetam bound to the ligand binding domain of GluA3 | Descriptor: | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, GLUTAMIC ACID, GluA2 S1S2 domain, ... | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2010-02-13 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
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1EES
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![BU of 1ees by Molmil](/molmil-images/mine/1ees) | SOLUTION STRUCTURE OF CDC42HS COMPLEXED WITH A PEPTIDE DERIVED FROM P-21 ACTIVATED KINASE, NMR, 20 STRUCTURES | Descriptor: | GTP-BINDING PROTEIN, P21-ACTIVATED KINASE | Authors: | Gizachew, D, Guo, W, Chohan, K.C, Sutcliffe, M.J, Oswald, R.E. | Deposit date: | 2000-02-02 | Release date: | 2000-03-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase. Biochemistry, 39, 2000
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4F22
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![BU of 4f22 by Molmil](/molmil-images/mine/4f22) | |
2KB0
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![BU of 2kb0 by Molmil](/molmil-images/mine/2kb0) | Cdc42(T35A) | Descriptor: | Cell division control protein 42 homolog | Authors: | Adams, P.D, Oswald, R.E, McFeeters, R. | Deposit date: | 2008-11-18 | Release date: | 2009-12-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Cdc42(T35A) To be Published
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4GXS
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![BU of 4gxs by Molmil](/molmil-images/mine/4gxs) | Ligand binding domain of GluA2 (AMPA/glutamate receptor) bound to (-)-kaitocephalin | Descriptor: | (5R)-2-[(1S,2R)-2-amino-2-carboxy-1-hydroxyethyl]-5-{(2S)-2-carboxy-2-[(3,5-dichloro-4-hydroxybenzoyl)amino]ethyl}-L-proline, Glutamate receptor 2, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-09-04 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9634 Å) | Cite: | The structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2. J.Biol.Chem., 287, 2012
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4Q30
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![BU of 4q30 by Molmil](/molmil-images/mine/4q30) | Nitrowillardiine bound to the ligand binding domain of GluA2 at pH 3.5 | Descriptor: | 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, Glutamate receptor 2 CHIMERIC PROTEIN, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2014-04-10 | Release date: | 2014-06-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Thermodynamics and mechanism of the interaction of willardiine partial agonists with a glutamate receptor: implications for drug development. Biochemistry, 53, 2014
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7TOD
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![BU of 7tod by Molmil](/molmil-images/mine/7tod) | Solution structure of the phosphatidylinositol 3-phosphate binding domain from the Legionella effector SetA | Descriptor: | Subversion of eukaryotic traffic protein A | Authors: | Beck, W.H.J, Enoki, T.A, Feigenson, G.W, Nicholson, L, Oswald, R, Mao, Y. | Deposit date: | 2022-01-24 | Release date: | 2023-02-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the phosphatidylinositol 3-phosphate binding domain from the Legionella effector SetA To Be Published
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1AJE
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![BU of 1aje by Molmil](/molmil-images/mine/1aje) | CDC42 FROM HUMAN, NMR, 20 STRUCTURES | Descriptor: | CDC42HS | Authors: | Feltham, J.L, Dotsch, V, Raza, S, Manor, D, Cerione, R.A, Sutcliffe, M.J, Wagner, G, Oswald, R.E. | Deposit date: | 1997-05-02 | Release date: | 1997-11-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Definition of the switch surface in the solution structure of Cdc42Hs. Biochemistry, 36, 1997
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4F29
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![BU of 4f29 by Molmil](/molmil-images/mine/4f29) | Quisqualate bound to the ligand binding domain of GluA3i | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-05-07 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51, 2012
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4F1Y
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![BU of 4f1y by Molmil](/molmil-images/mine/4f1y) | CNQX bound to the ligand binding domain of GluA3 | Descriptor: | 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 3, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-05-07 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51, 2012
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4F2Q
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![BU of 4f2q by Molmil](/molmil-images/mine/4f2q) | Quisqualate bound to the D655A mutant of the ligand binding domain of GluA3 | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-05-08 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51, 2012
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4F3B
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![BU of 4f3b by Molmil](/molmil-images/mine/4f3b) | |
4F31
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![BU of 4f31 by Molmil](/molmil-images/mine/4f31) | |
4F39
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![BU of 4f39 by Molmil](/molmil-images/mine/4f39) | Kainate bound to the ligand binding domain of GluA3 | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 3, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-05-09 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.834 Å) | Cite: | The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51, 2012
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4F2O
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![BU of 4f2o by Molmil](/molmil-images/mine/4f2o) | Quisqualate bound to the D655A mutant of the ligand binding domain of GluA3 | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-05-08 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.912 Å) | Cite: | The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51, 2012
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4F3G
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![BU of 4f3g by Molmil](/molmil-images/mine/4f3g) | Kainate bound to the ligand binding domain of GluA3i | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 3, ZINC ION | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2012-05-09 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.064 Å) | Cite: | The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51, 2012
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2MOG
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![BU of 2mog by Molmil](/molmil-images/mine/2mog) | Solution structure of the terminal Ig-like domain from Leptospira interrogans LigB | Descriptor: | Bacterial Ig-like domain, group 2 | Authors: | Ptak, C.P, Hsieh, C, Lin, Y, Maltsev, A.S, Raman, R, Sharma, Y, Oswald, R.E, Chang, Y. | Deposit date: | 2014-04-25 | Release date: | 2014-08-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of the Terminal Immunoglobulin-like Domain from the Leptospira Host-Interacting Outer Membrane Protein, LigB. Biochemistry, 53, 2014
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3T9U
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![BU of 3t9u by Molmil](/molmil-images/mine/3t9u) | |
3LSF
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![BU of 3lsf by Molmil](/molmil-images/mine/3lsf) | Piracetam bound to the ligand binding domain of GluA2 | Descriptor: | 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ... | Authors: | Ahmed, A.H, Ptak, C.P, Oswald, R.E. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
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3LSL
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![BU of 3lsl by Molmil](/molmil-images/mine/3lsl) | Piracetam bound to the ligand binding domain of GluA2 (flop form) | Descriptor: | 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ... | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.122 Å) | Cite: | Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
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2ASE
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![BU of 2ase by Molmil](/molmil-images/mine/2ase) | |
3H06
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![BU of 3h06 by Molmil](/molmil-images/mine/3h06) | |