4F22
Kainate bound to the K660A mutant of the ligand binding domain of GluA3
Summary for 4F22
Entry DOI | 10.2210/pdb4f22/pdb |
Related | 4F1Y 4F29 4F2O 4F2Q 4F31 |
Descriptor | Glutamate receptor 3, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ZINC ION, ... (4 entities in total) |
Functional Keywords | glutamate receptor, glua3, glur3, ampa receptor, s1s2, lbd, neurotransmitter receptor, kainate, transport protein, transport protein-agonist complex, transport protein/agonist |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : P19492 |
Total number of polymer chains | 1 |
Total formula weight | 29176.95 |
Authors | Ahmed, A.H.,Oswald, R.E. (deposition date: 2012-05-07, release date: 2012-05-16, Last modification date: 2023-09-13) |
Primary citation | Holley, S.M.,Ahmed, A.H.,Srinivasan, J.,Murthy, S.E.,Weiland, G.A.,Oswald, R.E.,Nowak, L.M. The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51:4015-4027, 2012 Cited by PubMed: 22512472DOI: 10.1021/bi3001837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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