4F22

Kainate bound to the K660A mutant of the ligand binding domain of GluA3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glutamate receptor 3	polymer	258	28898.3	1	UniProt (P19492) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (rat)	GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3
2	B (A)	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE	non-polymer		213.2	1	Chemie (KAI)
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	D (A)	water	water		18.0	235	Chemie (HOH)

Sequence modifications

A: 4 - 117 (UniProt: P19492)
A: 120 - 261 (UniProt: P19492)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Ala 144	Lys 682	engineered mutation
Thr 232	Asn 770	SEE REMARK 999
Pro 233	Ala 771	SEE REMARK 999
Ser 242	Asn 780	SEE REMARK 999
Ile 246	Leu 784	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28898.3
Non-Polymers*	Number of molecules	2
	Total formula weight	278.6
All*	Total formula weight	29177.0

*Water molecules are not included.