6TB4
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![BU of 6tb4 by Molmil](/molmil-images/mine/6tb4) | Structure of SAGA bound to TBP | Descriptor: | SAGA-associated factor 73 (Sgf73), Spt20, Subunit (17 kDa) of TFIID and SAGA complexes, ... | Authors: | Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. | Deposit date: | 2019-10-31 | Release date: | 2020-01-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of SAGA and mechanism of TBP deposition on gene promoters. Nature, 577, 2020
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6TGV
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![BU of 6tgv by Molmil](/molmil-images/mine/6tgv) | Crystal structure of Mycobacterium smegmatis CoaBC in complex with CTP and FMN | Descriptor: | 1,2-ETHANEDIOL, CYTIDINE-5'-TRIPHOSPHATE, Coenzyme A biosynthesis bifunctional protein CoaBC, ... | Authors: | Mendes, V, Blaszczyk, M, Bryant, O, Cory-Wright, J, Blundell, T.L. | Deposit date: | 2019-11-18 | Release date: | 2020-11-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nat Commun, 12, 2021
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6UWF
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![BU of 6uwf by Molmil](/molmil-images/mine/6uwf) | GltPh in complex with L-aspartate and sodium ions in outward-facing state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Wang, X, Boudker, O. | Deposit date: | 2019-11-05 | Release date: | 2020-06-03 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Use of paramagnetic 19 F NMR to monitor domain movement in a glutamate transporter homolog. Nat.Chem.Biol., 16, 2020
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1YUO
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![BU of 1yuo by Molmil](/molmil-images/mine/1yuo) | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua) | Descriptor: | Uracil-DNA glycosylase | Authors: | Moe, E, Leiros, I, Riise, E.K, Olufsen, M, Lanes, O, Smalas, A.O, Willassen, N.P. | Deposit date: | 2005-02-14 | Release date: | 2005-03-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua) J.Mol.Biol., 343, 2004
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1YNJ
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![BU of 1ynj by Molmil](/molmil-images/mine/1ynj) | Taq RNA polymerase-Sorangicin complex | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. | Deposit date: | 2005-01-24 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
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2IT8
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![BU of 2it8 by Molmil](/molmil-images/mine/2it8) | |
6VBB
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![BU of 6vbb by Molmil](/molmil-images/mine/6vbb) | 2.60 Angstrom Resolution Crystal Structure of Peptidase S41 from Acinetobacter baumannii | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Peptidase S41, ... | Authors: | Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-12-18 | Release date: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | 2.60 Angstrom Resolution Crystal Structure of Peptidase S41 from Acinetobacter baumannii To Be Published
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6UWL
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![BU of 6uwl by Molmil](/molmil-images/mine/6uwl) | |
1X6J
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![BU of 1x6j by Molmil](/molmil-images/mine/1x6j) | Crystal structure of ygfY from Escherichia coli | Descriptor: | Hypothetical protein ygfY | Authors: | Lim, K, Doseeva, V, Sarikaya Demirkan, E, Pullalarevu, S, Krajewski, W, Galkin, A, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | Deposit date: | 2004-08-11 | Release date: | 2005-02-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the YgfY from Escherichia coli, a protein that may be involved in transcriptional regulation Proteins, 58, 2005
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1XG3
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![BU of 1xg3 by Molmil](/molmil-images/mine/1xg3) | Crystal structure of the C123S 2-methylisocitrate lyase mutant from Escherichia coli in complex with the reaction product, Mg(II)-pyruvate and succinate | Descriptor: | MAGNESIUM ION, PYRUVIC ACID, Probable methylisocitrate lyase, ... | Authors: | Liu, S, Lu, Z, Han, Y, Melamud, E, Dunaway-Mariano, D, Herzberg, O. | Deposit date: | 2004-09-16 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate Specificity, Catalysis and Evolution Biochemistry, 44, 2005
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1XFH
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![BU of 1xfh by Molmil](/molmil-images/mine/1xfh) | |
1XG4
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![BU of 1xg4 by Molmil](/molmil-images/mine/1xg4) | Crystal Structure of the C123S 2-Methylisocitrate Lyase Mutant from Escherichia coli in complex with the inhibitor isocitrate | Descriptor: | ISOCITRIC ACID, MAGNESIUM ION, Probable methylisocitrate lyase | Authors: | Liu, S, Lu, Z, Han, Y, Melamud, E, Dunaway-Mariano, D, Herzberg, O. | Deposit date: | 2004-09-16 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate Specificity, Catalysis and Evolution Biochemistry, 44, 2005
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1XR0
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![BU of 1xr0 by Molmil](/molmil-images/mine/1xr0) | Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors | Descriptor: | Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1 | Authors: | Dhalluin, C, Yan, K.S, Plotnikova, O, Lee, K.W, Zeng, L, Kuti, M, Mujtaba, S, Goldfarb, M.P, Zhou, M.-M. | Deposit date: | 2004-10-13 | Release date: | 2004-11-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors Mol.Cell, 6, 2000
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1XR9
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![BU of 1xr9 by Molmil](/molmil-images/mine/1xr9) | Crystal Structures of HLA-B*1501 in Complex with Peptides from Human UbcH6 and Epstein-Barr Virus EBNA-3 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Roder, G, Blicher, T, Johannessen, B.R, Kristensen, O, Buus, S, Gajhede, M. | Deposit date: | 2004-10-14 | Release date: | 2005-04-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.788 Å) | Cite: | Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype Acta Crystallogr.,Sect.D, 62, 2006
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1XTI
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![BU of 1xti by Molmil](/molmil-images/mine/1xti) | Structure of Wildtype human UAP56 | Descriptor: | ISOPROPYL ALCOHOL, Probable ATP-dependent RNA helicase p47 | Authors: | Shi, H, Cordin, O, Minder, C.M, Linder, P, Xu, R.M. | Deposit date: | 2004-10-21 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of the human ATP-dependent splicing and export factor UAP56 Proc.Natl.Acad.Sci.Usa, 101, 2004
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6SPT
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![BU of 6spt by Molmil](/molmil-images/mine/6spt) | High resolution crystal structure of N-terminal domain of PEX14 from Trypanosoma brucei in complex with the fist compound with sub-micromolar trypanocidal activity | Descriptor: | 5-[(4-methoxynaphthalen-1-yl)methyl]-1-[2-[(2-methyl-1-oxidanyl-propan-2-yl)amino]ethyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Napolitano, V, Dawidowski, M, Kalel, V.C, Fino, R, Emmanouilidis, L, Lenhart, D, Ostertag, M, Kaiser, M, Kolonko, M, Schilebs, W, Maser, P, Tetko, I, Hadian, K, Plettenburg, O, Erdmann, R, Sattler, M, Popowicz, G.M, Dubin, G. | Deposit date: | 2019-09-02 | Release date: | 2020-01-01 | Last modified: | 2020-02-05 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity. J.Med.Chem., 63, 2020
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6SUP
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![BU of 6sup by Molmil](/molmil-images/mine/6sup) | Crystal Structure of TcdB2-TccC3-Cdc42 | Descriptor: | MAGNESIUM ION, TcdB2,TccC3,Cell division control protein 42 homolog | Authors: | Roderer, D, Schubert, E, Sitsel, O, Raunser, S. | Deposit date: | 2019-09-16 | Release date: | 2019-12-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Towards the application of Tc toxins as a universal protein translocation system. Nat Commun, 10, 2019
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1XNI
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![BU of 1xni by Molmil](/molmil-images/mine/1xni) | Tandem Tudor Domain of 53BP1 | Descriptor: | Tumor suppressor p53-binding protein 1 | Authors: | Huyen, Y, Zgheib, O, DiTullio Jr, R.A, Gorgoulis, V.G, Zacharatos, P, Petty, T.J, Sheston, E.A, Mellert, H.S, Stavridi, E.S, Halazonetis, T.D. | Deposit date: | 2004-10-05 | Release date: | 2004-11-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks Nature, 432, 2004
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6SUQ
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![BU of 6suq by Molmil](/molmil-images/mine/6suq) | Crystal Structure of TcdB2-TccC3-TEV | Descriptor: | TcdB2,TccC3,Genome polyprotein | Authors: | Roderer, D, Schubert, E, Sitsel, O, Raunser, S. | Deposit date: | 2019-09-16 | Release date: | 2019-12-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Towards the application of Tc toxins as a universal protein translocation system. Nat Commun, 10, 2019
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1Y8F
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![BU of 1y8f by Molmil](/molmil-images/mine/1y8f) | |
6V8G
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![BU of 6v8g by Molmil](/molmil-images/mine/6v8g) | GltPh mutant - Y204L A345V V366A | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Boudker, O, Huysmans, G.H.M. | Deposit date: | 2019-12-11 | Release date: | 2020-11-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | The high-energy transition state of the glutamate transporter homologue GltPh. Embo J., 40, 2021
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2W5Q
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![BU of 2w5q by Molmil](/molmil-images/mine/2w5q) | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE | Authors: | Lu, D, Wormann, M.E, Zhang, X, Scheewind, O, Grundling, A, Freemont, P.S. | Deposit date: | 2008-12-11 | Release date: | 2009-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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1Y53
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![BU of 1y53 by Molmil](/molmil-images/mine/1y53) | Crystal structure of bacterial expressed avidin related protein 4 (AVR4) C122S | Descriptor: | Avidin-related protein 4/5, FORMIC ACID | Authors: | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | Deposit date: | 2004-12-02 | Release date: | 2005-05-24 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr.,Sect.D, 61, 2005
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1YI3
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![BU of 1yi3 by Molmil](/molmil-images/mine/1yi3) | Crystal Structure of Pim-1 bound to LY294002 | Descriptor: | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Jacobs, M.D, Black, J, Futer, O, Swenson, L, Hare, B, Fleming, M, Saxena, K. | Deposit date: | 2005-01-11 | Release date: | 2005-01-25 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002. J.Biol.Chem., 280, 2005
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6VBF
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![BU of 6vbf by Molmil](/molmil-images/mine/6vbf) | 1.85 Angstrom Resolution Crystal Structure of N-terminal Domain of Two-component System Response Regulator from Acinetobacter baumannii | Descriptor: | CALCIUM ION, CHLORIDE ION, Two-component regulatory system response regulator | Authors: | Minasov, G, Shuvalova, L, Kiryukhina, O, Wiersum, G, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-12-18 | Release date: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1.85 Angstrom Resolution Crystal Structure of N-terminal Domain of Two-component System Response Regulator from Acinetobacter baumannii To Be Published
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