4FR4
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![BU of 4fr4 by Molmil](/molmil-images/mine/4fr4) | Crystal structure of human serine/threonine-protein kinase 32A (YANK1) | Descriptor: | 1,2-ETHANEDIOL, STAUROSPORINE, Serine/threonine-protein kinase 32A | Authors: | Chaikuad, A, Elkins, J.M, Krojer, T, Mahajan, P, Goubin, S, Szklarz, M, Tumber, A, Wang, J, Savitsky, P, Shrestha, B, Daga, N, Picaud, S, Fedorov, O, Allerston, C.K, Latwiel, S.V.A, Vollmar, M, Canning, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2012-06-26 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of human serine/threonine-protein kinase 32A (YANK1) To be Published
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5LCD
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![BU of 5lcd by Molmil](/molmil-images/mine/5lcd) | Structure of Polyphosphate Kinase from Meiothermus ruber bound to AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Gerhardt, S, Einsle, O, Kemper, F, Schwarzer, N. | Deposit date: | 2016-06-21 | Release date: | 2017-06-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ABX
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4JJ6
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![BU of 4jj6 by Molmil](/molmil-images/mine/4jj6) | Crystal structure of a catalytic mutant of Axe2 (Axe2-H194A), an acetylxylan esterase from Geobacillus stearothermophilus | Descriptor: | Acetyl xylan esterase, CHLORIDE ION, GLYCEROL | Authors: | Lansky, S, Alalouf, O, Solomon, V, Alhassid, A, Belrahli, H, Govada, L, Chayan, N.E, Shoham, Y, Shoham, G. | Deposit date: | 2013-03-07 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | To be published To be published
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5LD1
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![BU of 5ld1 by Molmil](/molmil-images/mine/5ld1) | Crystal Structure of Polyphosphate Kinase from Meiothermus ruber bound to ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Gerhardt, S, Einsle, O, Kemper, F, Schwarzer, N. | Deposit date: | 2016-06-23 | Release date: | 2017-06-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4FBL
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![BU of 4fbl by Molmil](/molmil-images/mine/4fbl) | LipS and LipT, two metagenome-derived lipolytic enzymes increase the diversity of known lipase and esterase families | Descriptor: | CHLORIDE ION, LipS lipolytic enzyme, SPERMIDINE | Authors: | Chow, J, Krauss, U, Dall Antonia, Y, Fersini, F, Schmeisser, C, Schmidt, M, Menyes, I, Bornscheuer, U, Lauinger, B, Bongen, P, Pietruszka, J, Eckstein, M, Thum, O, Liese, A, Mueller-Dieckmann, J, Jaeger, K.-E, Kovacic, F, Streit, W.R, Structural Proteomics in Europe (SPINE) | Deposit date: | 2012-05-23 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases. Plos One, 7, 2012
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4JBF
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![BU of 4jbf by Molmil](/molmil-images/mine/4jbf) | Crystal structure of peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469. | Descriptor: | Peptidoglycan glycosyltransferase, TETRAETHYLENE GLYCOL | Authors: | Filippova, E.V, Wawrzak, Z, Minasov, G, Shuvalova, L, Kiryukhina, O, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | Deposit date: | 2013-02-19 | Release date: | 2013-03-20 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Crystal structure of peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469. To be Published
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4GTY
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![BU of 4gty by Molmil](/molmil-images/mine/4gty) | Crystal structure of mouse Enpp1 in complex with GMP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-29 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
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5A47
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![BU of 5a47 by Molmil](/molmil-images/mine/5a47) | Structure of Thaumatin obtained by multi crystal data collection | Descriptor: | L(+)-TARTARIC ACID, THAUMATIN-1 | Authors: | Zander, U, Bourenkov, G, Popov, A.N, de Sanctis, D, McCarthy, A.A, Svensson, O, Round, E.S, Gordeliy, V.I, Mueller-Dieckmann, C, Leonard, G.A. | Deposit date: | 2015-06-05 | Release date: | 2015-11-11 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Meshandcollect: An Automated Multi-Crystal Data-Collection Workflow for Synchrotron Macromolecular Crystallography Beamlines. Acta Crystallogr.,Sect.D, 71, 2015
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5A9F
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![BU of 5a9f by Molmil](/molmil-images/mine/5a9f) | Crystal structure of the Helicase domain of human DNA polymerase theta in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA POLYMERASE THETA, MAGNESIUM ION, ... | Authors: | Newman, J.A, Cooper, C.D.O, Aitkenhead, H, Pinkas, D.M, Kupinska, K, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2015-07-21 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. Structure, 23, 2015
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5AA5
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![BU of 5aa5 by Molmil](/molmil-images/mine/5aa5) | Actinobacterial-type NiFe-hydrogenase from Ralstonia eutropha H16 at 2.85 Angstrom resolution | Descriptor: | IRON/SULFUR CLUSTER, MALONIC ACID, NIFE-HYDROGENASE LARGE SUBUNIT, ... | Authors: | Schaefer, C, Bommer, M, Hennig, S, Jeoung, J.H, Dobbek, H, Lenz, O. | Deposit date: | 2015-07-23 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Structure of an Actinobacterial-Type [Nife]-Hydrogenase Reveals Insight Into O2-Tolerant H2 Oxidation. Structure, 24, 2016
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5ABB
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![BU of 5abb by Molmil](/molmil-images/mine/5abb) | Visualization of a polytopic membrane protein during SecY-mediated membrane insertion | Descriptor: | GREEN-LIGHT ABSORBING PROTEORHODOPSIN, PROTEIN TRANSLOCASE SUBUNIT SECE, PROTEIN TRANSLOCASE SUBUNIT SECY | Authors: | Bischoff, L, Wickles, S, Berninghausen, O, vanderSluis, E, Beckmann, R. | Deposit date: | 2015-08-05 | Release date: | 2015-08-19 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Visualization of a Polytopic Membrane Protein During Secy-Mediated Membrane Insertion. Nat.Commun., 5, 2014
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5ACS
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![BU of 5acs by Molmil](/molmil-images/mine/5acs) | Y233A-Investigation of the impact from residues W228 and Y233 in the metallo-beta-lactamase GIM-1 | Descriptor: | GIM-1 PROTEIN, ZINC ION | Authors: | Skagseth, S, Carlsen, T.J, Bjerga, G.E.K, Spencer, J, Samuelsen, O, Leiros, H.-K.S. | Deposit date: | 2015-08-17 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.459 Å) | Cite: | Role of Residues W228 and Y233 in the Structure and Activity of Metallo-Beta-Lactamase Gim-1. Antimicrob.Agents Chemother., 60, 2015
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4H3U
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![BU of 4h3u by Molmil](/molmil-images/mine/4h3u) | Crystal structure of hypothetical protein with ketosteroid isomerase-like protein fold from Catenulispora acidiphila DSM 44928 | Descriptor: | ACETATE ION, CADMIUM ION, CHLORIDE ION, ... | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-09-14 | Release date: | 2012-10-03 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural characterization of a hypothetical protein: a potential agent involved in trimethylamine metabolism in Catenulispora acidiphila. J.Struct.Funct.Genom., 15, 2014
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5J3Y
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![BU of 5j3y by Molmil](/molmil-images/mine/5j3y) | Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex | Descriptor: | mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1 | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.288 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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5A14
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![BU of 5a14 by Molmil](/molmil-images/mine/5a14) | Human CDK2 with type II inhibitor | Descriptor: | 1-[4-(2-azanylpyrimidin-4-yl)oxyphenyl]-3-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]urea, CYCLIN-DEPENDENT KINASE 2 | Authors: | Alexander, L.T, Elkins, J.M, Kopec, J, Fedorov, O, Savitsky, P.A, Moebitz, H, Cowan-Jacob, S.W, Szklarz, M, Pike, A.C.W, Carpenter, E.P, Krojer, T, Bountra, C, Edwards, A.M, Knapp, S. | Deposit date: | 2015-04-27 | Release date: | 2015-07-22 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Type II Inhibitors Targeting Cdk2. Acs Chem.Biol., 10, 2015
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5IZ1
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![BU of 5iz1 by Molmil](/molmil-images/mine/5iz1) | Physcomitrella patens FBPase | Descriptor: | fructose-1,6-bisphosphatase | Authors: | Einsle, O, Guetle, D. | Deposit date: | 2016-03-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Chloroplast FBPase and SBPase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories. Proc.Natl.Acad.Sci.USA, 113, 2016
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5A3Y
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![BU of 5a3y by Molmil](/molmil-images/mine/5a3y) | SAD structure of Thermolysin obtained by multi crystal data collection | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ... | Authors: | Zander, U, Bourenkov, G, Popov, A.N, de Sanctis, D, McCarthy, A.A, Svensson, O, Round, E.S, Gordeliy, V.I, Mueller-Dieckmann, C, Leonard, G.A. | Deposit date: | 2015-06-04 | Release date: | 2015-11-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Meshandcollect: An Automated Multi-Crystal Data-Collection Workflow for Synchrotron Macromolecular Crystallography Beamlines. Acta Crystallogr.,Sect.D, 71, 2015
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5ABY
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![BU of 5aby by Molmil](/molmil-images/mine/5aby) | Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli | Descriptor: | 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ... | Authors: | Peter, D, Weichenrieder, O. | Deposit date: | 2015-08-09 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation Genes Dev., 29, 2015
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4HD0
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![BU of 4hd0 by Molmil](/molmil-images/mine/4hd0) | Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair | Descriptor: | DNA double-strand break repair protein Mre11, MANGANESE (II) ION | Authors: | Limbo, O, Moiani, D, Kertokalio, A, Wyman, C, Tainer, J.A, Russell, P. | Deposit date: | 2012-10-01 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Nucleic Acids Res., 40, 2012
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4GSN
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5A1S
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![BU of 5a1s by Molmil](/molmil-images/mine/5a1s) | Crystal structure of the sodium-dependent citrate symporter SeCitS form Salmonella enterica. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, CITRATE ANION, ... | Authors: | Woehlert, D, Groetzinger, M.J, Kuhlbrandt, W, Yildiz, O. | Deposit date: | 2015-05-05 | Release date: | 2016-02-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanism of Na(+)-dependent citrate transport from the structure of an asymmetrical CitS dimer. Elife, 4, 2015
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4L4Q
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![BU of 4l4q by Molmil](/molmil-images/mine/4l4q) | Methionine Adenosyltransferase | Descriptor: | S-adenosylmethionine synthase | Authors: | Schlesier, J, Siegrist, J, Gerhardt, S, Andexer, J.N, Einsle, O. | Deposit date: | 2013-06-09 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional characterisation of the methionine adenosyltransferase from Thermococcus kodakarensis. Bmc Struct.Biol., 13, 2013
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4GUP
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![BU of 4gup by Molmil](/molmil-images/mine/4gup) | Structure of MHC-class I related molecule MR1 | Descriptor: | 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ... | Authors: | Patel, O, Le Nours, J, Rossjohn, J. | Deposit date: | 2012-08-29 | Release date: | 2012-10-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | MR1 presents microbial vitamin B metabolites to MAIT cells Nature, 491, 2012
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5A3Z
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![BU of 5a3z by Molmil](/molmil-images/mine/5a3z) | Structure of monoclinic Lysozyme obtained by multi crystal data collection | Descriptor: | GLYCEROL, LYSOZYME, NITRATE ION | Authors: | Zander, U, Bourenkov, G, Popov, A.N, de Sanctis, D, McCarthy, A.A, Svensson, O, Round, E.S, Gordeliy, V.I, Mueller-Dieckmann, C, Leonard, G.A. | Deposit date: | 2015-06-04 | Release date: | 2015-11-11 | Last modified: | 2015-11-25 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Meshandcollect: An Automated Multi-Crystal Data-Collection Workflow for Synchrotron Macromolecular Crystallography Beamlines. Acta Crystallogr.,Sect.D, 71, 2015
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