3HBB
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![BU of 3hbb by Molmil](/molmil-images/mine/3hbb) | Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate | 分子名称: | 1,2-ETHANEDIOL, Dihydrofolate reductase-thymidylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schormann, N, Senkovich, O, Chattopadhyay, D. | 登録日 | 2009-05-04 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate. Acta Crystallogr.,Sect.D, 65, 2009
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3HFU
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![BU of 3hfu by Molmil](/molmil-images/mine/3hfu) | Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide | 分子名称: | 1,2-ETHANEDIOL, AZIDE ION, HTH-type transcriptional regulator cynR | 著者 | Singer, A.U, Evdokimova, E, Kagan, O, Dong, A, Edwards, A.M, Savchenko, A. | 登録日 | 2009-05-12 | 公開日 | 2009-06-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide TO BE PUBLISHED
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1KXG
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![BU of 1kxg by Molmil](/molmil-images/mine/1kxg) | The 2.0 Ang Resolution Structure of BLyS, B Lymphocyte Stimulator. | 分子名称: | 1,4-DIETHYLENE DIOXIDE, B lymphocyte stimulator, CITRIC ACID, ... | 著者 | Oren, D.A, Li, Y, Volovik, Y, Morris, T.S, Dharia, C, Das, K, Galperina, O, Gentz, R, Arnold, E. | 登録日 | 2002-01-31 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of BLyS receptor recognition. Nat.Struct.Biol., 9, 2002
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3HFR
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![BU of 3hfr by Molmil](/molmil-images/mine/3hfr) | Crystal structure of glutamate racemase from Listeria monocytogenes | 分子名称: | CHLORIDE ION, Glutamate racemase, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) | 著者 | Majorek, K.A, Chruszcz, M, Zimmerman, M.D, Klimecka, M.M, Cymborowski, M, Skarina, T, Onopriyenko, O, Stam, J, Otwinowski, Z, Anderson, W.F, Savchenko, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-05-12 | 公開日 | 2009-06-09 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of glutamate racemase from Listeria monocytogenes TO BE PUBLISHED
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6F2F
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![BU of 6f2f by Molmil](/molmil-images/mine/6f2f) | Crystal structure of Protease 1 from Pyrococcus Horikoshii co-cystallized in presence of 10 mM Tb-Xo4 and ammonium sulfate. | 分子名称: | Deglycase PH1704, Dihydroxyacetone, SULFATE ION, ... | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Franzetti, B, Girard, E, Dumont, E, Maury, O. | 登録日 | 2017-11-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
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3HE6
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4C67
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![BU of 4c67 by Molmil](/molmil-images/mine/4c67) | Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains | 分子名称: | 1,2-ETHANEDIOL, 13-methyl-7-phenyl-3-thia-1,8,11,12-tetraazatricyclo trideca-2(6),4,7,10,12-pentaene, BROMODOMAIN-CONTAINING PROTEIN 4 | 著者 | Chung, C, Mirguet, O. | 登録日 | 2013-09-17 | 公開日 | 2013-10-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Discovery of Epigenetic Regulator I-Bet762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the Bet Bromodomains. J.Med.Chem., 56, 2013
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1KO2
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![BU of 1ko2 by Molmil](/molmil-images/mine/1ko2) | VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa with an oxidized Cys (cysteinesulfonic) | 分子名称: | ACETATE ION, VIM-2 metallo-beta-lactamase, ZINC ION | 著者 | Garcia-Saez, I, Docquier, J.-D, Rossolini, G.M, Dideberg, O. | 登録日 | 2001-12-20 | 公開日 | 2003-09-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form J.Mol.Biol., 375, 2008
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3HJ7
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![BU of 3hj7 by Molmil](/molmil-images/mine/3hj7) | Crystal structure of TILS C-terminal domain | 分子名称: | CHLORIDE ION, tRNA(Ile)-lysidine synthase | 著者 | Nakanishi, K, Bonnefond, L, Kimura, S, Suzuki, T, Ishitani, R, Nureki, O. | 登録日 | 2009-05-21 | 公開日 | 2009-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase. Nature, 461, 2009
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1KTV
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![BU of 1ktv by Molmil](/molmil-images/mine/1ktv) | |
6F2J
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![BU of 6f2j by Molmil](/molmil-images/mine/6f2j) | Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM sodium sulfate | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION, ... | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Girard, E, Dumont, E, Maury, O. | 登録日 | 2017-11-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
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6FEA
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6F5D
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![BU of 6f5d by Molmil](/molmil-images/mine/6f5d) | Trypanosoma brucei F1-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma subunit, ATP synthase subunit alpha, ... | 著者 | Montgomery, M.G, Gahura, O, Leslie, A.G.W, Zikova, A, Walker, J.E. | 登録日 | 2017-12-01 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | ATP synthase fromTrypanosoma bruceihas an elaborated canonical F1-domain and conventional catalytic sites. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3HIM
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![BU of 3him by Molmil](/molmil-images/mine/3him) | The Crystal Structure of a Bacterial Regulatory Protein in the tetR Family from Rhodococcus RHA1 to 2.2A | 分子名称: | Probable transcriptional regulator | 著者 | Stein, A.J, Binkowski, T.A, Evdokimova, E, Kagan, O, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-05-20 | 公開日 | 2009-05-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Crystal Structure of a Bacterial Regulatory Protein in the tetR Family from Rhodococcus RHA1 to 2.2A To be Published
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6ET9
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![BU of 6et9 by Molmil](/molmil-images/mine/6et9) | Structure of the acetoacetyl-CoA-thiolase/HMG-CoA-synthase complex from Methanothermococcus thermolithotrophicus at 2.75 A | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acetyl-CoA acetyltransferase thiolase, CHLORIDE ION, ... | 著者 | Engilberge, S, Voegeli, B, Girard, E, Riobe, F, Maury, O, Erb, T.J, Shima, S, Wagner, T. | 登録日 | 2017-10-25 | 公開日 | 2018-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1M4P
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![BU of 1m4p by Molmil](/molmil-images/mine/1m4p) | Structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP "late domain" peptide, DYANA Ensemble | 分子名称: | Gag Polyprotein, Tumor Susceptibility gene 101 protein | 著者 | Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-07-03 | 公開日 | 2002-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein Nat.Struct.Biol., 9, 2002
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1M85
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![BU of 1m85 by Molmil](/molmil-images/mine/1m85) | Structure of Proteus mirabilis catalase for the native form | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | 著者 | Gouet, P, Jouve, H.-M, Dideberg, O. | 登録日 | 2002-07-24 | 公開日 | 2002-08-14 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Proteus mirabilis PR catalase with and without bound NADPH. J.Mol.Biol., 249, 1995
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3IED
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![BU of 3ied by Molmil](/molmil-images/mine/3ied) | Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN | 分子名称: | AMP PHOSPHORAMIDATE, Heat shock protein | 著者 | Pizarro, J.C, Wernimont, A.K, Lew, J, Hutchinson, A, Artz, J.D, Amaya, M.F, Plotnikova, O, Vedadi, M, Kozieradzki, I, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Botchkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | 登録日 | 2009-07-22 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN TO BE PUBLISHED
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1HO2
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![BU of 1ho2 by Molmil](/molmil-images/mine/1ho2) | NMR STRUCTURE OF THE POTASSIUM CHANNEL FRAGMENT L45 IN MICELLES | 分子名称: | VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN | 著者 | Ohlenschlager, O, Hojo, H, Ramachandran, R, Gorlach, M, Haris, P.I. | 登録日 | 2000-12-08 | 公開日 | 2002-06-05 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel. Biophys.J., 82, 2002
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6F2H
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![BU of 6f2h by Molmil](/molmil-images/mine/6f2h) | Structure of Protease 1 from Pyrococcus horikoshii co-crystallized in presence of 10 mM Tb-Xo4 and potassium iodide. | 分子名称: | Deglycase PH1704, IODIDE ION, TERBIUM(III) ION, ... | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Franzetti, B, Girard, E, Dumont, E, Maury, O. | 登録日 | 2017-11-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
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3IGK
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![BU of 3igk by Molmil](/molmil-images/mine/3igk) | Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 2) | 分子名称: | Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ZINC ION | 著者 | Suad, O, Rabinovich, D, Rozenberg, H, Shakked, Z. | 登録日 | 2009-07-28 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
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6F58
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![BU of 6f58 by Molmil](/molmil-images/mine/6f58) | Crystal structure of human Brachyury (T) in complex with DNA | 分子名称: | Brachyury protein, DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*TP*T)-3'), SODIUM ION | 著者 | Newman, J.A, Gavard, A.E, Krojer, T, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2017-12-01 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.253 Å) | 主引用文献 | Crystal structure of human Brachyury (T) in complex with DNA To Be Published
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1HUY
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![BU of 1huy by Molmil](/molmil-images/mine/1huy) | CRYSTAL STRUCTURE OF CITRINE, AN IMPROVED YELLOW VARIANT OF GREEN FLUORESCENT PROTEIN | 分子名称: | GREEN FLUORESCENT PROTEIN | 著者 | Griesbeck, O, Baird, G.S, Campbell, R.E, Zacharias, D.A, Tsien, R.Y. | 登録日 | 2001-01-04 | 公開日 | 2001-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications J.Biol.Chem., 276, 2001
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3IMI
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![BU of 3imi by Molmil](/molmil-images/mine/3imi) | 2.01 Angstrom resolution crystal structure of a HIT family protein from Bacillus anthracis str. 'Ames Ancestor' | 分子名称: | HIT family protein, SULFATE ION, ZINC ION | 著者 | Halavaty, A.S, Wawrzak, Z, Skarina, T, Onopriyenko, O, Gordon, E, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-08-10 | 公開日 | 2009-08-18 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | 2.01 Angstrom resolution crystal structure of a HIT family protein from Bacillus anthracis str. 'Ames Ancestor' To be Published
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1M2A
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![BU of 1m2a by Molmil](/molmil-images/mine/1m2a) | Crystal structure at 1.5 Angstroms resolution of the wild type thioredoxin-like [2Fe-2S] ferredoxin from Aquifex aeolicus | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, SULFATE ION, ZINC ION, ... | 著者 | Yeh, A.P, Ambroggio, X.I, Andrade, S.L.A, Einsle, O, Chatelet, C, Meyer, J, Rees, D.C. | 登録日 | 2002-06-22 | 公開日 | 2002-09-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | High-resolution crystal structures of the wild type and
Cys-55-->Ser and Cys-59-->Ser variants of the thioredoxin-like
[2Fe-2S] ferredoxin from Aquifex aeolicus J.Biol.Chem., 277, 2002
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