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PDB: 98 results

2SH1
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SOLUTION STRUCTURE OF NEUROTOXIN I FROM THE SEA ANEMONE STICHODACTYLA HELIANTHUS. A NUCLEAR MAGNETIC RESONANCE, DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS STUDY
Descriptor: NEUROTOXIN I
Authors:Fogh, R.H, Norton, R.S.
Deposit date:1990-05-03
Release date:1991-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study.
J.Biol.Chem., 265, 1990
2GX1
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Solution structure and alanine scan of a spider toxin that affects the activation of mammalian sodium channels
Descriptor: Neurotoxin magi-5
Authors:Sabo, J.K, Corzo, G, Bosmans, F, Billen, B, Villegas, E, Tytgat, J, Norton, R.S.
Deposit date:2006-05-08
Release date:2006-12-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure and Alanine Scan of a Spider Toxin That Affects the Activation of Mammalian Voltage-gated Sodium Channels
J.Biol.Chem., 282, 2007
5WCV
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AsK132958: A minimal homologue of ShK identified in the transcriptome of Anemonia sulcata
Descriptor: ShK homolog AsK132958
Authors:Krishnarjuna, B, MacRaild, C.A, Norton, R.S.
Deposit date:2017-07-02
Release date:2017-10-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.
Peptides, 99, 2018
8SEM
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Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni
Descriptor: TRPV1 inhibitory peptide Tst2
Authors:Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
Deposit date:2023-04-10
Release date:2023-09-27
Method:SOLUTION NMR
Cite:Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
8SED
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Structure of a new ShKT peptide from the sea anemone Telmatactis stephensoni: ShKT-Ts1
Descriptor: ShKT peptide ShKT-Ts1
Authors:Sanches, K, Siedoks, A.A, Wai, D.C.C, Norton, R.S.
Deposit date:2023-04-09
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Structure-function relationships in ShKT domain peptides: ShKT-Ts1 from the sea anemone Telmatactis stephensoni.
Proteins, 92, 2024
8F04
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Structure of elevenin-Vc1 from venom of the Australian cone snail Conus victoriae
Descriptor: Elevenin-Vc1
Authors:Krishnarjuna, B, Sunanda, P, Norton, R.S.
Deposit date:2022-11-01
Release date:2023-09-13
Method:SOLUTION NMR
Cite:Characterisation of Elevenin-Vc1 from the Venom of Conus victoriae : A Structural Analogue of alpha-Conotoxins.
Mar Drugs, 21, 2023
5JYQ
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Structure of Conus Geographus insulin G1
Descriptor: Insulin 1, Insulin 1b, SULFATE ION
Authors:Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
Deposit date:2016-05-15
Release date:2016-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
4QXT
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with FC27-MSP2 14-30
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-22
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4QY8
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-24
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.353 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4QYO
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-24
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.208 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4R3S
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23
Descriptor: FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-08-18
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate
Sci Rep, 5, 2015
1OWT
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Structure of the Alzheimer's disease amyloid precursor protein copper binding domain
Descriptor: Amyloid beta A4 protein
Authors:Barnham, K.J, McKinstry, W.J, Multhaup, G, Galatis, D, Morton, C.J, Curtain, C.C, Williamson, N.A, White, A.R, Hinds, M.G, Norton, R.S, Beyreuther, K, Masters, C.L, Parker, M.W, Cappai, R.
Deposit date:2003-03-30
Release date:2003-05-13
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain. A REGULATOR OF NEURONAL COPPER HOMEOSTASIS.
J.Biol.Chem., 278, 2003
6DN5
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SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor
Descriptor: SPRY domain-containing SOCS box protein 2, SULFATE ION, WDINNN(BAL) cyclic peptide inhibitor
Authors:Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
Deposit date:2018-06-06
Release date:2019-04-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6DN8
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SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor
Descriptor: (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ...
Authors:Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
Deposit date:2018-06-06
Release date:2019-04-17
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
7KNN
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Solution structure of the alpha-conotoxin analogue [2-8]-alkyne Vc1.1
Descriptor: Alpha-conotoxin Vc1a
Authors:MacRaild, C.A, Robinson, S.D, Chhabra, S, Norton, R.S.
Deposit date:2020-11-05
Release date:2021-09-15
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Alkyne-Bridged alpha-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
J.Med.Chem., 64, 2021
1KD6
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Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II
Descriptor: EQUINATOXIN II
Authors:Hinds, M.G, Zhang, W, Anderluh, G, Hansen, P.E, Norton, R.S.
Deposit date:2001-11-12
Release date:2002-02-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
J.Mol.Biol., 315, 2002
5TBD
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BU of 5tbd by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222
Descriptor: Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2
Authors:Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S.
Deposit date:2016-09-12
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.
J. Mol. Biol., 429, 2017
3EK9
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BU of 3ek9 by Molmil
SPRY Domain-containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding
Descriptor: GLYCEROL, SPRY domain-containing SOCS box protein 2
Authors:Kuang, Z, Yao, S, Xu, Y, Garrett, T.J.P, Norton, R.S.
Deposit date:2008-09-19
Release date:2009-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
J.Mol.Biol., 386, 2009
1IXT
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BU of 1ixt by Molmil
Structure of a Novel P-Superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif
Descriptor: spasmodic protein tx9a-like protein
Authors:Miles, L.A, Dy, C.Y, Nielsen, J, Barnham, K.J, Hinds, M.G, Olivera, B.M, Bulaj, G, Norton, R.S.
Deposit date:2002-07-04
Release date:2003-01-28
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of a Novel P-Superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif
J.Biol.Chem., 277, 2002
2AFJ
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SPRY domain-containing SOCS box protein 2 (SSB-2)
Descriptor: gene rich cluster, C9 gene
Authors:Masters, S.L, Yao, S, Willson, T.A, Zhang, J.G, Palmer, K.R, Smith, B.J, Babon, J.J, Nicola, N.A, Norton, R.S, Nicholson, S.E.
Deposit date:2005-07-26
Release date:2006-01-03
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues
Nat.Struct.Mol.Biol., 13, 2006
1YXE
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BU of 1yxe by Molmil
Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical membrane antigen 1
Descriptor: apical membrane antigen 1
Authors:Feng, Z.P, Keizer, D.W, Stevenson, R.A, Yao, S, Babon, J.J, Murphy, V.J, Anders, R.F, Norton, R.S.
Deposit date:2005-02-21
Release date:2005-07-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Inter-domain Interactions of Domain II from the Blood-stage Malarial Protein, Apical Membrane Antigen 1.
J.Mol.Biol., 350, 2005
1ZEC
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BU of 1zec by Molmil
NMR Solution structure of NEF1-25, 20 structures
Descriptor: NEF1-25
Authors:Barnham, K.J, Monks, S.A, Hinds, M.G, Azad, A.A, Norton, R.S.
Deposit date:1996-12-18
Release date:1998-01-07
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:Solution structure of a polypeptide from the N terminus of the HIV protein Nef.
Biochemistry, 36, 1997
1IGL
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BU of 1igl by Molmil
SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS
Descriptor: INSULIN-LIKE GROWTH FACTOR II
Authors:Torres, A.M, Forbes, B.E, Aplin, S.E, Wallace, J.C, Francis, G.L, Norton, R.S.
Deposit date:1994-12-29
Release date:1995-02-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions.
J.Mol.Biol., 248, 1995
2CCO
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BU of 2cco by Molmil
STRUCTURE OF THE CALCIUM CHANNEL BLOCKER OMEGA CONOTOXIN GVIA, NMR, 20 STRUCTURES
Descriptor: OMEGA-CONOTOXIN GVIA
Authors:Pallaghy, P.K, Norton, R.S.
Deposit date:1998-02-13
Release date:1998-07-15
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Refined solution structure of omega-conotoxin GVIA: implications for calcium channel binding
J.Pept.Res., 53, 1999
2BBU
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solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor
Descriptor: GP130 PHOSPHOPEPTIDE, Suppressor of cytokine signaling 3
Authors:Babon, J.J, Yao, S, Norton, R.S.
Deposit date:2005-10-17
Release date:2006-05-02
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability
Mol.Cell, 22, 2006

 

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