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PDB: 98 件

4Z0E
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Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038TRN] peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
4Z0D
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Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038Trp] peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
1IXT
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Structure of a Novel P-Superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif
分子名称: spasmodic protein tx9a-like protein
著者Miles, L.A, Dy, C.Y, Nielsen, J, Barnham, K.J, Hinds, M.G, Olivera, B.M, Bulaj, G, Norton, R.S.
登録日2002-07-04
公開日2003-01-28
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of a Novel P-Superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif
J.Biol.Chem., 277, 2002
1SHI
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REFINED STRUCTURE IN SOLUTION OF THE SEA ANEMONE NEUROTOXIN SHI
分子名称: NEUROTOXIN I
著者Pallaghy, P.K, Dyke, T.R, Norton, R.S.
登録日1994-12-07
公開日1995-02-07
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Refined structure in solution of the sea anemone neurotoxin ShI.
J.Biol.Chem., 268, 1993
6Y1U
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Mycobacterium tuberculosis FtsZ-GDP in complex with 4-hydroxycoumarin
分子名称: 4-HYDROXY-2H-CHROMEN-2-ONE, Cell division protein FtsZ, DIMETHYL SULFOXIDE, ...
著者Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F.
登録日2020-02-13
公開日2021-06-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
6Y1V
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Mycobacterium tuberculosis FtsZ-GTP-gamma-S in complex with 4-hydroxycoumarin
分子名称: 4-HYDROXY-2H-CHROMEN-2-ONE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein FtsZ, ...
著者Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F.
登録日2020-02-13
公開日2021-06-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
4Y1S
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Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
分子名称: CALCIUM ION, Perforin-1
著者Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S.
登録日2015-02-09
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.611 Å)
主引用文献Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J.Biol.Chem., 290, 2015
4Y1T
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Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
分子名称: CALCIUM ION, Perforin-1
著者Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S.
登録日2015-02-09
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.666 Å)
主引用文献Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J.Biol.Chem., 290, 2015
6DN7
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SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor
分子名称: CHLORIDE ION, SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6DN6
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SPRY domain-containing SOCS box protein 2 complexed with INNN(ABU) cyclic peptide inhibitor
分子名称: INNN(ABU) cyclic peptide inhibitor, SPRY domain-containing SOCS box protein 2
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6CKF
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Structure of a new ShKT peptide from the sea anemone Oulactis sp: OspTx2a-p2
分子名称: OspTx2a-p2
著者Sunanda, P, Krishnarjuna, B, Norton, R.S.
登録日2018-02-28
公開日2019-03-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification, chemical synthesis, structure, and function of a new KV1 channel blocking peptide from Oulactis sp.
Peptide Science, 110, 2018
6CKD
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Structure of a new ShKT peptide from the sea anemone Oulactis sp: OspTx2a-p1
分子名称: OspTx2a-p1
著者Sunanda, P, Krishnarjuna, B, Norton, R.S.
登録日2018-02-27
公開日2019-02-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification, chemical synthesis, structure, and function of a new KV1 channel blocking peptide from Oulactis sp.
Peptide Science, 110, 2018
2AFJ
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SPRY domain-containing SOCS box protein 2 (SSB-2)
分子名称: gene rich cluster, C9 gene
著者Masters, S.L, Yao, S, Willson, T.A, Zhang, J.G, Palmer, K.R, Smith, B.J, Babon, J.J, Nicola, N.A, Norton, R.S, Nicholson, S.E.
登録日2005-07-26
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues
Nat.Struct.Mol.Biol., 13, 2006
6UX5
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Structure of acrorhagin I from the sea anemone Actinia equina
分子名称: U-actitoxin-Aeq5a
著者Krishnarjuna, B, Sunanda, P, Norton, R.S.
登録日2019-11-06
公開日2020-11-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A disulfide-stabilised helical hairpin fold in acrorhagin I: An emerging structural motif in peptide toxins.
J.Struct.Biol., 213, 2020
6YM1
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Mycobacterium tuberculosis FtsZ in complex with GDP
分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
著者Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F.
登録日2020-04-07
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
6YM9
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Mycobacterium tuberculosis FtsZ in complex with GTP-gamma-S
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein FtsZ
著者Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F.
登録日2020-04-08
公開日2021-04-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
2JRY
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Structure and Sodium Channel Activity of an Excitatory I1-Superfamily Conotoxin
分子名称: I-superfamily conotoxin r11a
著者Buczek, O, Wei, D, Babon, J, Yang, X, Fiedler, B, Chen, P, Yoshikami, D, Olivera, B, Bulaj, G, Norton, R.
登録日2007-06-29
公開日2007-10-23
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Biochemistry, 46, 2007
1RMJ
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C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II
分子名称: Insulin-like growth factor binding protein 6
著者Headey, S.J, Keizer, D.W, Yao, S, Brasier, G, Kantharidis, P, Bach, L.A, Norton, R.S.
登録日2003-11-28
公開日2004-09-14
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II.
Mol.Endocrinol., 18, 2004
4QXT
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with FC27-MSP2 14-30
分子名称: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-07-22
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4QYO
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22
分子名称: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-07-24
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.208 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4R3S
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23
分子名称: FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-08-18
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate
Sci Rep, 5, 2015
4QY8
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Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30
分子名称: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-07-24
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.353 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4R1B
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Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1, AMA1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
4R1C
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Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1, AMA1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
4R19
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Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1, AMA1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014

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