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PDB: 98 件

4Z09
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Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Thr2040Ala] peptide
分子名称: Apical membrane antigen 1, GLYCEROL, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
6DN8
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SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor
分子名称: (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ...
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6DN5
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SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor
分子名称: SPRY domain-containing SOCS box protein 2, SULFATE ION, WDINNN(BAL) cyclic peptide inhibitor
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
1AHL
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ANTHOPLEURIN-A,NMR, 20 STRUCTURES
分子名称: ANTHOPLEURIN-A
著者Pallaghy, P.K, Scanlon, M.J, Monks, S.A, Norton, R.S.
登録日1994-10-28
公開日1995-11-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Three-dimensional structure in solution of the polypeptide cardiac stimulant anthopleurin-A.
Biochemistry, 34, 1995
1OWT
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Structure of the Alzheimer's disease amyloid precursor protein copper binding domain
分子名称: Amyloid beta A4 protein
著者Barnham, K.J, McKinstry, W.J, Multhaup, G, Galatis, D, Morton, C.J, Curtain, C.C, Williamson, N.A, White, A.R, Hinds, M.G, Norton, R.S, Beyreuther, K, Masters, C.L, Parker, M.W, Cappai, R.
登録日2003-03-30
公開日2003-05-13
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain. A REGULATOR OF NEURONAL COPPER HOMEOSTASIS.
J.Biol.Chem., 278, 2003
1ANS
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THREE-DIMENSIONAL STRUCTURE IN SOLUTION OF NEUROTOXIN III FROM THE SEA ANEMONE ANEMONIA SULCATA
分子名称: NEUROTOXIN III
著者Manoleras, N, Norton, R.S.
登録日1994-06-09
公開日1994-08-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Three-dimensional structure in solution of neurotoxin III from the sea anemone Anemonia sulcata.
Biochemistry, 33, 1994
1APF
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ANTHOPLEURIN-B, NMR, 20 STRUCTURES
分子名称: ANTHOPLEURIN-B
著者Monks, S.A, Pallaghy, P.K, Scanlon, M.J, Norton, R.S.
登録日1995-05-30
公開日1996-07-11
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A.
Structure, 3, 1995
1VIB
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NMR SOLUTION STRUCTURE OF THE NEUROTOXIN B-IV, 20 STRUCTURES
分子名称: NEUROTOXIN B-IV
著者Barnham, K.J, Dyke, T.R, Kem, W.R, Norton, R.S.
登録日1996-11-25
公開日1997-05-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding.
J.Mol.Biol., 268, 1997
2SH1
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SOLUTION STRUCTURE OF NEUROTOXIN I FROM THE SEA ANEMONE STICHODACTYLA HELIANTHUS. A NUCLEAR MAGNETIC RESONANCE, DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS STUDY
分子名称: NEUROTOXIN I
著者Fogh, R.H, Norton, R.S.
登録日1990-05-03
公開日1991-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study.
J.Biol.Chem., 265, 1990
5WCV
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AsK132958: A minimal homologue of ShK identified in the transcriptome of Anemonia sulcata
分子名称: ShK homolog AsK132958
著者Krishnarjuna, B, MacRaild, C.A, Norton, R.S.
登録日2017-07-02
公開日2017-10-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.
Peptides, 99, 2018
8SEM
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Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni
分子名称: TRPV1 inhibitory peptide Tst2
著者Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
登録日2023-04-10
公開日2023-09-27
実験手法SOLUTION NMR
主引用文献Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
8SED
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Structure of a new ShKT peptide from the sea anemone Telmatactis stephensoni: ShKT-Ts1
分子名称: ShKT peptide ShKT-Ts1
著者Sanches, K, Siedoks, A.A, Wai, D.C.C, Norton, R.S.
登録日2023-04-09
公開日2023-10-18
最終更新日2024-01-17
実験手法SOLUTION NMR
主引用文献Structure-function relationships in ShKT domain peptides: ShKT-Ts1 from the sea anemone Telmatactis stephensoni.
Proteins, 92, 2024
5JYQ
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Structure of Conus Geographus insulin G1
分子名称: Insulin 1, Insulin 1b, SULFATE ION
著者Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
登録日2016-05-15
公開日2016-09-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
8F04
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Structure of elevenin-Vc1 from venom of the Australian cone snail Conus victoriae
分子名称: Elevenin-Vc1
著者Krishnarjuna, B, Sunanda, P, Norton, R.S.
登録日2022-11-01
公開日2023-09-13
実験手法SOLUTION NMR
主引用文献Characterisation of Elevenin-Vc1 from the Venom of Conus victoriae : A Structural Analogue of alpha-Conotoxins.
Mar Drugs, 21, 2023
7KNN
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Solution structure of the alpha-conotoxin analogue [2-8]-alkyne Vc1.1
分子名称: Alpha-conotoxin Vc1a
著者MacRaild, C.A, Robinson, S.D, Chhabra, S, Norton, R.S.
登録日2020-11-05
公開日2021-09-15
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Alkyne-Bridged alpha-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
J.Med.Chem., 64, 2021
1A3P
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ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
分子名称: EPIDERMAL GROWTH FACTOR
著者Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R.
登録日1998-01-22
公開日1998-07-29
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
1YXE
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Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical membrane antigen 1
分子名称: apical membrane antigen 1
著者Feng, Z.P, Keizer, D.W, Stevenson, R.A, Yao, S, Babon, J.J, Murphy, V.J, Anders, R.F, Norton, R.S.
登録日2005-02-21
公開日2005-07-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure and Inter-domain Interactions of Domain II from the Blood-stage Malarial Protein, Apical Membrane Antigen 1.
J.Mol.Biol., 350, 2005
6OQP
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U-AITx-Ate1
分子名称: SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE
著者Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
登録日2019-04-28
公開日2019-07-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Toxicon, 168, 2019
5TBD
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Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222
分子名称: Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2
著者Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S.
登録日2016-09-12
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.
J. Mol. Biol., 429, 2017
3EK9
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SPRY Domain-containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding
分子名称: GLYCEROL, SPRY domain-containing SOCS box protein 2
著者Kuang, Z, Yao, S, Xu, Y, Garrett, T.J.P, Norton, R.S.
登録日2008-09-19
公開日2009-02-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
J.Mol.Biol., 386, 2009
1A7M
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LEUKAEMIA INHIBITORY FACTOR CHIMERA (MH35-LIF), NMR, 20 STRUCTURES
分子名称: LEUKEMIA INHIBITORY FACTOR
著者Hinds, M.G, Maurer, T, Zhang, J.-G, Nicola, N.A, Norton, R.S.
登録日1998-03-16
公開日1999-04-20
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of leukemia inhibitory factor.
J.Biol.Chem., 273, 1998
1KD6
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Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II
分子名称: EQUINATOXIN II
著者Hinds, M.G, Zhang, W, Anderluh, G, Hansen, P.E, Norton, R.S.
登録日2001-11-12
公開日2002-02-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
J.Mol.Biol., 315, 2002
1IGL
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SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS
分子名称: INSULIN-LIKE GROWTH FACTOR II
著者Torres, A.M, Forbes, B.E, Aplin, S.E, Wallace, J.C, Francis, G.L, Norton, R.S.
登録日1994-12-29
公開日1995-02-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions.
J.Mol.Biol., 248, 1995
6MJV
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A consensus human beta defensin
分子名称: Human beta-defensin
著者Amero, C, Villegas-Moreno, J, Rodriguez, A, Norton, R.S, Corzo, G.
登録日2018-09-22
公開日2019-08-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Antimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10.
Proteins, 88, 2020
4Z0F
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Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038(6CW)] peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016

 

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