5YFM
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5YFN
| Human isocitrate dehydrogenase 1 bound with isocitrate | 分子名称: | ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, MAGNESIUM ION, ... | 著者 | Nordlund, P, Chen, D, Jansson, A, Larsson, A. | 登録日 | 2017-09-21 | 公開日 | 2017-10-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human isocitrate dehydrogenase 1 bound with isocitrate To Be Published
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5X5A
| Human thymidylate synthase bound with phosphate ion | 分子名称: | PHOSPHATE ION, Thymidylate synthase | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | 登録日 | 2017-02-15 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
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5X66
| Human thymidylate synthase in complex with dUMP and methotrexate | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, METHOTREXATE, Thymidylate synthase | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | 登録日 | 2017-02-21 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states J. Biol. Chem., 292, 2017
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1MRR
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1MXR
| High resolution structure of Ribonucleotide reductase R2 from E. coli in its oxidised (Met) form | 分子名称: | FE (III) ION, GLYCEROL, MERCURY (II) ION, ... | 著者 | Andersson, M.A, Hogbom, M, Nordlund, P. | 登録日 | 2002-10-03 | 公開日 | 2003-03-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-A x-ray data. Proc.Natl.Acad.Sci.Usa, 100, 2003
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3KVH
| Crystal structure of human protein syndesmos (NUDT16-like protein) | 分子名称: | CHLORIDE ION, GLYCEROL, Protein syndesmos | 著者 | Tresaugues, L, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Kotzsch, A, Kraulis, P, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Roos, A.K, Schuler, H, Schutz, P, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2009-11-30 | 公開日 | 2010-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of human protein syndesmos (NUDT16L1) To be Published
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1MH9
| Crystal Structure Analysis of deoxyribonucleotidase | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, deoxyribonucleotidase | 著者 | Rinaldo-Matthis, A, Rampazzo, C, Reichard, P, Bianchi, V, Nordlund, P. | 登録日 | 2002-08-19 | 公開日 | 2002-10-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of a human mitochondrial deoxyribonucleotidase. Nat.Struct.Biol., 9, 2002
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2FVZ
| Human Inositol Monophosphosphatase 2 | 分子名称: | Inositol monophosphatase 2 | 著者 | Ogg, D, Hallberg, B.M, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Kursula, P, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Van Den Berg, S, Weigelt, J, Thorsell, A.G, Structural Genomics Consortium (SGC) | 登録日 | 2006-01-31 | 公開日 | 2006-02-21 | 最終更新日 | 2018-05-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of Human Inositol Monophosphatase 2 To be published
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1MMO
| CRYSTAL STRUCTURE OF A BACTERIAL NON-HAEM IRON HYDROXYLASE THAT CATALYSES THE BIOLOGICAL OXIDATION OF METHANE | 分子名称: | ACETIC ACID, FE (III) ION, METHANE MONOOXYGENASE HYDROLASE (ALPHA CHAIN), ... | 著者 | Rosenzweig, A.C, Frederick, C.A, Lippard, S.J, Nordlund, P. | 登録日 | 1994-02-22 | 公開日 | 1995-02-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane. Nature, 366, 1993
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2G62
| Crystal structure of human PTPA | 分子名称: | GLYCEROL, SULFATE ION, protein phosphatase 2A, ... | 著者 | Magnusdottir, A, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Hogbom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P. | 登録日 | 2006-02-24 | 公開日 | 2006-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of a human PP2A phosphatase activator reveals a novel fold and highly conserved cleft implicated in protein-protein interactions. J.Biol.Chem., 281, 2006
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2QQ2
| Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7 | 分子名称: | Cytosolic acyl coenzyme A thioester hydrolase | 著者 | Busam, R, Lehtio, L, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Herman, M.D, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC) | 登録日 | 2007-07-26 | 公開日 | 2007-08-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Human acyl-CoA thioesterase 7. To be Published
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4XAL
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3C5N
| Structure of human TULP1 in complex with IP3 | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Tubby-related protein 1 | 著者 | Busam, R.D, Lehtio, L, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-01-31 | 公開日 | 2008-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human TULP1 in complex with IP3 To be published
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5WRN
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3CC6
| Crystal structure of kinase domain of protein tyrosine kinase 2 beta (PTK2B) | 分子名称: | GLYCEROL, MAGNESIUM ION, Protein tyrosine kinase 2 beta | 著者 | Busam, R.D, Lehtio, L, Karlberg, T, Arrowsmith, C.H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Helleday, T, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-02-25 | 公開日 | 2008-03-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of Protein Tyrosine Kinase 2 Beta (PTK2B) Kinase domain. To be Published
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2FRX
| Crystal structure of YebU, a m5C RNA methyltransferase from E.coli | 分子名称: | Hypothetical protein yebU | 著者 | Erlandsen, H, Nordlund, P, Hallberg, B.M, Johnson, K.A, Ericsson, U.B. | 登録日 | 2006-01-20 | 公開日 | 2006-08-29 | 最終更新日 | 2018-05-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain J.Mol.Biol., 360, 2006
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4TPJ
| Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | 分子名称: | ALA-ALA-ALA, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ... | 著者 | Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. | 登録日 | 2014-06-07 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
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4TPH
| Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | 分子名称: | 3,5 DIBROMOTYROSINE, ALANINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. | 登録日 | 2014-06-07 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.155 Å) | 主引用文献 | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
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4TPG
| Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | 分子名称: | Ala-L-3-Br-Tyr-Ala, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ... | 著者 | Guettou, F, Quistgaard, E.M, Raba, M, Moberg, P, Low, C, Nordlund, P. | 登録日 | 2014-06-07 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.91 Å) | 主引用文献 | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
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4MXE
| Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA | 分子名称: | ACETYL COENZYME *A, N-acetyltransferase ESCO1 | 著者 | Karlberg, T, Wisniewska, M, Thorsell, A.G, Kouznetsova, E, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Svensson, L, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2013-09-26 | 公開日 | 2015-04-08 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis. Structure, 24, 2016
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5HS3
| Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol, Thymidylate synthase | 著者 | Chen, D, Almqvist, H, Axelsson, H, Jafari, R, Mateus, A, Haraldsson, M, Larsson, A, Artursson, P, Molina, D.M, Lundback, T, Nordlund, P. | 登録日 | 2016-01-25 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.103 Å) | 主引用文献 | CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil Nat Commun, 7, 2016
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5EBE
| Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with 5' CMP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-O-phosphono-beta-D-ribofuranose, ... | 著者 | Lim, S.M, Yeung, K, Tresaugues, L, Teo, H.L, Nordlund, P. | 登録日 | 2015-10-19 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. Febs J., 283, 2016
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1HS6
| STRUCTURE OF LEUKOTRIENE A4 HYDROLASE COMPLEXED WITH BESTATIN. | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ACETATE ION, IMIDAZOLE, ... | 著者 | Thunnissen, M.M.G.M, Nordlund, P.N, Haeggstrom, J.Z. | 登録日 | 2000-12-24 | 公開日 | 2001-06-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation. Nat.Struct.Biol., 8, 2001
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5IPX
| Structure of ORF49 from KSHV | 分子名称: | ORF49 protein, SULFATE ION | 著者 | Hew, K, Nordlund, P. | 登録日 | 2016-03-10 | 公開日 | 2016-11-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Open Reading Frame 49 Protein Encoded by Kaposi's Sarcoma-Associated Herpesvirus. J. Virol., 91, 2017
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