1SHF
 
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1SHG
 | | CRYSTAL STRUCTURE OF A SRC-HOMOLOGY 3 (SH3) DOMAIN | | 分子名称: | ALPHA-SPECTRIN SH3 DOMAIN | | 著者 | Noble, M, Pauptit, R, Musacchio, A, Saraste, M, Wierenga, R.K. | | 登録日 | 1993-05-19 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a Src-homology 3 (SH3) domain.
Nature, 359, 1992
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3LTW
 | | The structure of mycobacterium marinum arylamine n-acetyltransferase in complex with hydralazine | | 分子名称: | 1-hydrazinophthalazine, Arylamine N-acetyltransferase Nat, FORMIC ACID | | 著者 | Abuhammad, A.M, Lowe, E.D, Fullam, E, Noble, M, Garman, E.F, Sim, E. | | 登録日 | 2010-02-16 | | 公開日 | 2010-07-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site
Protein Cell, 1, 2010
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2PMO
 | | Crystal structure of PfPK7 in complex with hymenialdisine | | 分子名称: | 4-(5-AMINO-4-OXO-4H-PYRAZOL-3-YL)-2-BROMO-4,5,6,7-TETRAHYDRO-3AH-PYRROLO[2,3-C]AZEPIN-8-ONE, Ser/Thr protein kinase | | 著者 | Merckx, A, Echalier, A, Noble, M, Endicott, J. | | 登録日 | 2007-04-23 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design.
Structure, 16, 2008
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2PMN
 | | Crystal structure of PfPK7 in complex with an ATP-site inhibitor | | 分子名称: | 4-(6-{[(1S)-1-(HYDROXYMETHYL)-2-METHYLPROPYL]AMINO}IMIDAZO[1,2-B]PYRIDAZIN-3-YL)BENZONITRILE, Ser/Thr protein kinase, putative | | 著者 | Merckx, A, Echalier, A, Noble, M, Endicott, J. | | 登録日 | 2007-04-23 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design.
Structure, 16, 2008
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2PML
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1UUH
 | | Hyaluronan binding domain of human CD44 | | 分子名称: | CD44 ANTIGEN | | 著者 | Teriete, P, Banerji, S, Noble, M, Blundell, C, Wright, A, Pickford, A, Lowe, E, Mahoney, D, Tammi, M, Kahmann, J, Campbell, I, Day, A, Jackson, D. | | 登録日 | 2003-12-19 | | 公開日 | 2004-03-04 | | 最終更新日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the Regulatory Hyaluronan-Binding Domain in the Inflammatory Leukocyte Homing Receptor Cd44
Mol.Cell, 13, 2004
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1GX3
 | | M. smegmatis arylamine N-acetyl transferase | | 分子名称: | ARYLAMINE N-ACETYLTRANSFERASE | | 著者 | Sandy, J, Mushtaq, A, Kawamura, A, Sinclair, J, Sim, E, Noble, M. | | 登録日 | 2002-03-26 | | 公開日 | 2002-06-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Structure of Arylamine N-Acetyltransferase from Mycobacterium Smegmatis-an Enzyme which Inactivates the Anti-Tubercular Drug, Isoniazid
J.Mol.Biol., 318, 2002
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1OB3
 | | Structure of P. falciparum PfPK5 | | 分子名称: | CELL DIVISION CONTROL PROTEIN 2 HOMOLOG | | 著者 | Holton, S, Merckx, A, Burgess, D, Doerig, C, Noble, M, Endicott, J. | | 登録日 | 2003-01-24 | | 公開日 | 2004-01-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition
Structure, 11, 2003
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1V0P
 | | Structure of P. falciparum PfPK5-Purvalanol B ligand complex | | 分子名称: | CELL DIVISION CONTROL PROTEIN 2 HOMOLOG, PURVALANOL B | | 著者 | Holton, S, Merckx, A, Burgess, D, Doerig, C, Noble, M, Endicott, J. | | 登録日 | 2004-04-01 | | 公開日 | 2004-05-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition
Structure, 11, 2003
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1V0B
 | | Crystal structure of the t198a mutant of pfpk5 | | 分子名称: | CELL DIVISION CONTROL PROTEIN 2 HOMOLOG | | 著者 | Holton, S, Merckx, A, Burgess, D, Doerig, C, Noble, M, Endicott, J. | | 登録日 | 2004-03-26 | | 公開日 | 2004-03-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition
Structure, 11, 2003
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1V0O
 | | Structure of P. falciparum PfPK5-Indirubin-5-sulphonate ligand complex | | 分子名称: | 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, CELL DIVISION CONTROL PROTEIN 2 HOMOLOG | | 著者 | Holton, S, Merckx, A, Burgess, D, Doerig, C, Noble, M, Endicott, J. | | 登録日 | 2004-03-31 | | 公開日 | 2004-04-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition
Structure, 11, 2003
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1GZ8
 | | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 2-Amino-6-(3'-methyl-2'-oxo)butoxypurine | | 分子名称: | 1-[(2-AMINO-6,9-DIHYDRO-1H-PURIN-6-YL)OXY]-3-METHYL-2-BUTANOL, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Davies, T, Endicott, J, Johnson, L, Noble, M, Tucker, J. | | 登録日 | 2002-05-17 | | 公開日 | 2003-06-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives
J.Med.Chem., 45, 2002
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