2PMO

Crystal structure of PfPK7 in complex with hymenialdisine

Summary for 2PMO

Entry DOI	10.2210/pdb2pmo/pdb
Descriptor	Ser/Thr protein kinase, 4-(5-AMINO-4-OXO-4H-PYRAZOL-3-YL)-2-BROMO-4,5,6,7-TETRAHYDRO-3AH-PYRROLO[2,3-C]AZEPIN-8-ONE (3 entities in total)
Functional Keywords	ser/thr protein kinase; plasmodium falciparum; transferase; phosphorylation, transferase
Biological source	Plasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains	1
Total formula weight	41758.73
Authors	Merckx, A.,Echalier, A.,Noble, M.,Endicott, J. (deposition date: 2007-04-23, release date: 2008-01-22, Last modification date: 2023-08-30)
Primary citation	Merckx, A.,Echalier, A.,Langford, K.,Sicard, A.,Langsley, G.,Joore, J.,Doerig, C.,Noble, M.,Endicott, J. Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design. Structure, 16:228-238, 2008 Cited by PubMed: 18275814 DOI: 10.1016/j.str.2007.11.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation