8SDQ
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8SDX
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![BU of 8sdx by Molmil](/molmil-images/mine/8sdx) | ATAD2B bromodomain in complex with histone H4 acetylated at lysine 5 with Serine 1 mutation to Cysteine | Descriptor: | ATPase family AAA domain-containing protein 2B, SULFATE ION, histone H4S1CK5ac | Authors: | Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C. | Deposit date: | 2023-04-07 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67, 2024
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8SDO
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8UHL
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![BU of 8uhl by Molmil](/molmil-images/mine/8uhl) | ATAD2B bromodomain in complex with histone H4 acetylated at lysine 12 | Descriptor: | ATPase family AAA domain-containing protein 2B, Histone H4 | Authors: | Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C. | Deposit date: | 2023-10-09 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67, 2024
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8UK5
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![BU of 8uk5 by Molmil](/molmil-images/mine/8uk5) | Crystal structure of the bromodomain of human ATAD2B in complex with histone H4S1(ph)K5ac | Descriptor: | ATPase family AAA domain-containing protein 2B, Histone H4S1(ph)K5ac | Authors: | Montgomery, C, Phillips, M, Nix, J.C, Glass, K.C. | Deposit date: | 2023-10-12 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67, 2024
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7JX3
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![BU of 7jx3 by Molmil](/molmil-images/mine/7jx3) | Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab domain of monoclonal antibody S2H14, Heavy chain of Fab domain of monoclonal antibody S304, ... | Authors: | Snell, G, Czudnochowski, N, Rosen, L.E, Nix, J.C, Corti, D, Veesler, D, Park, Y.J, Walls, A.C, Tortorici, M.A, Cameroni, E, Pinto, D, Beltramello, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2020-08-26 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology. Cell, 183, 2020
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6MJ0
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![BU of 6mj0 by Molmil](/molmil-images/mine/6mj0) | Crystal structure of the complete turnip yellow mosaic virus 3'UTR | Descriptor: | RNA (101-MER) | Authors: | Hartwick, E.W, Costantino, D.A, MacFadden, A, Nix, J.C, Tian, S, Das, R, Kieft, J.S. | Deposit date: | 2018-09-20 | Release date: | 2019-01-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Ribosome-induced RNA conformational changes in a viral 3'-UTR sense and regulate translation levels. Nat Commun, 9, 2018
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7JJU
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![BU of 7jju by Molmil](/molmil-images/mine/7jju) | Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV) | Descriptor: | CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ... | Authors: | Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S. | Deposit date: | 2020-07-27 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold. Rna, 26, 2020
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5J9A
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![BU of 5j9a by Molmil](/molmil-images/mine/5j9a) | Ambient temperature transition state structure of arginine kinase - crystal 11/Form II | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ... | Authors: | Godsey, M, Davulcu, O, Nix, J, Skalicky, J.J, Bruschweiler, R, Chapman, M.S. | Deposit date: | 2016-04-08 | Release date: | 2016-08-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | The Sampling of Conformational Dynamics in Ambient-Temperature Crystal Structures of Arginine Kinase. Structure, 24, 2016
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2OXQ
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![BU of 2oxq by Molmil](/molmil-images/mine/2oxq) | Structure of the UbcH5 :CHIP U-box complex | Descriptor: | CHLORIDE ION, STIP1 homology and U-Box containing protein 1, Ubiquitin-conjugating enzyme E2D 1 | Authors: | Xu, Z, Nix, J.C, Devlin, K.I, Misra, S. | Deposit date: | 2007-02-20 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes. Bmc Struct.Biol., 8, 2008
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6OP6
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![BU of 6op6 by Molmil](/molmil-images/mine/6op6) | Structure of VIM-20 in the reduced state | Descriptor: | Metallo-beta-lactamase VIM-20, SODIUM ION, ZINC ION | Authors: | Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C. | Deposit date: | 2019-04-24 | Release date: | 2019-10-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions. Mbio, 10, 2019
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6OP7
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![BU of 6op7 by Molmil](/molmil-images/mine/6op7) | Structure of oxidized VIM-20 | Descriptor: | ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION | Authors: | Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C. | Deposit date: | 2019-04-24 | Release date: | 2019-10-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions. Mbio, 10, 2019
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6NHK
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![BU of 6nhk by Molmil](/molmil-images/mine/6nhk) | Mortalin nucleotide binding domain in the ADP-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Page, R.C, Moseng, M.A, Nix, J.C. | Deposit date: | 2018-12-23 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.777 Å) | Cite: | Biophysical Consequences of EVEN-PLUS Syndrome Mutations for the Function of Mortalin. J.Phys.Chem.B, 123, 2019
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7RNJ
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![BU of 7rnj by Molmil](/molmil-images/mine/7rnj) | S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide | Descriptor: | Monoclonal antibody S2P6 Fab heavy chain, Monoclonal antibody S2P6 Fab light chain, SULFATE ION, ... | Authors: | Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M, Sauer, M.M, Veesler, D. | Deposit date: | 2021-07-29 | Release date: | 2021-08-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Broad betacoronavirus neutralization by a stem helix-specific human antibody. Science, 373, 2021
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5GYJ
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![BU of 5gyj by Molmil](/molmil-images/mine/5gyj) | Structure of catalytically active sortase from Clostridium difficile | Descriptor: | Putative peptidase C60B, sortase B | Authors: | Yin, J.-C, Fei, C.-H, Hsiao, Y.-Y, Nix, J.C, Huang, I.-H, Wang, S. | Deposit date: | 2016-09-22 | Release date: | 2017-01-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structural Insights into Substrate Recognition by Clostridium difficile Sortase. Front Cell Infect Microbiol, 6, 2016
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2Q5G
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![BU of 2q5g by Molmil](/molmil-images/mine/2q5g) | Ligand binding domain of PPAR delta receptor in complex with a partial agonist | Descriptor: | Peroxisome proliferator-activated receptor delta, [(7-{[2-(3-MORPHOLIN-4-YLPROP-1-YN-1-YL)-6-{[4-(TRIFLUOROMETHYL)PHENYL]ETHYNYL}PYRIDIN-4-YL]THIO}-2,3-DIHYDRO-1H-INDEN- 4-YL)OXY]ACETIC ACID | Authors: | Pettersson, I, Sauerberg, P, Johansson, E, Hoffman, I, Tari, L.W, Hunter, M.J, Nix, J. | Deposit date: | 2007-06-01 | Release date: | 2008-06-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Design of a partial PPARdelta agonist. Bioorg.Med.Chem.Lett., 17, 2007
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5F16
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![BU of 5f16 by Molmil](/molmil-images/mine/5f16) | CTA-modified hen egg-white lysozyme | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | McGlone, C, Nix, J.C, Page, R.C. | Deposit date: | 2015-11-30 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates. Biomacromolecules, 17, 2016
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5F14
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![BU of 5f14 by Molmil](/molmil-images/mine/5f14) | Structure of native hen egg-white lysozyme | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | McGlone, C, Nix, J.C, Page, R.C. | Deposit date: | 2015-11-30 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.148 Å) | Cite: | Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates. Biomacromolecules, 17, 2016
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3CQX
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![BU of 3cqx by Molmil](/molmil-images/mine/3cqx) | Chaperone Complex | Descriptor: | BAG family molecular chaperone regulator 2, Heat shock cognate 71 kDa protein, SODIUM ION, ... | Authors: | Xu, Z, Nix, J.C, Misra, S. | Deposit date: | 2008-04-03 | Release date: | 2008-11-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2 Nat.Struct.Mol.Biol., 15, 2008
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3D0T
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4P5J
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![BU of 4p5j by Molmil](/molmil-images/mine/4p5j) | Crystal structure of the tRNA-like structure from Turnip Yellow Mosaic Virus (TYMV), a tRNA mimicking RNA | Descriptor: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, SPERMINE, ... | Authors: | Colussi, T.M, Costantino, D.A, Hammond, J.A, Ruehle, G.M, Nix, J.C, Kieft, J.S. | Deposit date: | 2014-03-17 | Release date: | 2014-06-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9912 Å) | Cite: | The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA. Nature, 511, 2014
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4PQV
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![BU of 4pqv by Molmil](/molmil-images/mine/4pqv) | Crystal structure of an Xrn1-resistant RNA from the 3' untranslated region of a flavivirus (Murray Valley Encephalitis virus) | Descriptor: | MAGNESIUM ION, XRN1-resistant flaviviral RNA | Authors: | Chapman, E.G, Costantino, D.A, Rabe, J.L, Moon, S.L, Wilusz, J, Nix, J.C, Kieft, J.S. | Deposit date: | 2014-03-04 | Release date: | 2014-04-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.463 Å) | Cite: | The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production. Science, 344, 2014
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3L28
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![BU of 3l28 by Molmil](/molmil-images/mine/3l28) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant | Descriptor: | CHLORIDE ION, Polymerase cofactor VP35, SODIUM ION, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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3L27
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![BU of 3l27 by Molmil](/molmil-images/mine/3l27) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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3L26
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![BU of 3l26 by Molmil](/molmil-images/mine/3l26) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Polymerase cofactor VP35, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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