7K0Q
| Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound | 分子名称: | Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0L
| Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound | 分子名称: | Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0P
| Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0M
| Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7K0I
| Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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7VSI
| Structure of human SGLT2-MAP17 complex bound with empagliflozin | 分子名称: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, PALMITIC ACID, PDZK1-interacting protein 1, ... | 著者 | Chen, L, Niu, Y, Liu, R. | 登録日 | 2021-10-26 | 公開日 | 2021-12-15 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter. Nature, 601, 2022
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7Y4S
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7WMV
| Structure of human SGLT1-MAP17 complex bound with LX2761 | 分子名称: | N-[2-(dimethylamino)ethyl]-2-methyl-2-[4-[4-[[2-methyl-5-[(2S,3R,4R,5S,6R)-6-methylsulfanyl-3,4,5-tris(oxidanyl)oxan-2-yl]phenyl]methyl]phenyl]butanoylamino]propanamide, PDZK1-interacting protein 1, Sodium/glucose cotransporter 1 | 著者 | Chen, L, Niu, Y, Cui, W. | 登録日 | 2022-01-17 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural mechanism of SGLT1 inhibitors. Nat Commun, 13, 2022
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