1YGU
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![BU of 1ygu by Molmil](/molmil-images/mine/1ygu) | Crystal structure of the tandem phosphatase domains of RPTP CD45 with a pTyr peptide | Descriptor: | Leukocyte common antigen, Polyoma Middle T antigen | Authors: | Nam, H, Poy, F, Saito, H, Frederick, C.A. | Deposit date: | 2005-01-05 | Release date: | 2005-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45. J.Exp.Med., 201, 2005
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2ABL
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![BU of 2abl by Molmil](/molmil-images/mine/2abl) | |
1YGR
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![BU of 1ygr by Molmil](/molmil-images/mine/1ygr) | Crystal structure of the tandem phosphatase domain of RPTP CD45 | Descriptor: | CD45 Protein Tyrosine Phosphatase, T-cell Receptor CD3 zeta ITAM-1 | Authors: | Nam, H.J, Poy, F, Saito, H, Frederick, C.A. | Deposit date: | 2005-01-05 | Release date: | 2005-02-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45. J.Exp.Med., 201, 2005
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3VKI
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![BU of 3vki by Molmil](/molmil-images/mine/3vki) | |
3VJP
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![BU of 3vjp by Molmil](/molmil-images/mine/3vjp) | |
6O3T
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![BU of 6o3t by Molmil](/molmil-images/mine/6o3t) | Structural basis of FOXC2 and DNA interactions | Descriptor: | DNA (5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein C2 | Authors: | Nam, H.-J, Li, S. | Deposit date: | 2019-02-27 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Crystal Structure of FOXC2 in Complex with DNA Target. Acs Omega, 4, 2019
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2QA0
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![BU of 2qa0 by Molmil](/molmil-images/mine/2qa0) | Structure of Adeno-Associated virus serotype 8 | Descriptor: | Capsid protein, SODIUM ION | Authors: | Nam, H.-J. | Deposit date: | 2007-06-14 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of adeno-associated virus serotype 8, a gene therapy vector. J.Virol., 81, 2007
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5BXF
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![BU of 5bxf by Molmil](/molmil-images/mine/5bxf) | Apo FcRn Structure at pH 4.5 | Descriptor: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51 | Authors: | Nam, H.-J, Taha, M. | Deposit date: | 2015-06-08 | Release date: | 2015-11-11 | Method: | X-RAY DIFFRACTION (2.851 Å) | Cite: | Human Fc-Receptor Neonatal at low pH gives insights into different states of FcRn To Be Published
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1LAR
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![BU of 1lar by Molmil](/molmil-images/mine/1lar) | CRYSTAL STRUCTURE OF THE TANDEM PHOSPHATASE DOMAINS OF RPTP LAR | Descriptor: | PROTEIN (LAR) | Authors: | Nam, H.-J, Poy, F, Krueger, N, Saito, H, Frederick, C.A. | Deposit date: | 1999-04-20 | Release date: | 2000-04-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the tandem phosphatase domains of RPTP LAR. Cell(Cambridge,Mass.), 97, 1999
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3RA8
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![BU of 3ra8 by Molmil](/molmil-images/mine/3ra8) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | Descriptor: | ADENOSINE MONOPHOSPHATE, Capsid protein | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | Deposit date: | 2011-03-27 | Release date: | 2011-09-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3RA2
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![BU of 3ra2 by Molmil](/molmil-images/mine/3ra2) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | Descriptor: | Capsid protein | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | Deposit date: | 2011-03-26 | Release date: | 2011-09-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3RA9
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![BU of 3ra9 by Molmil](/molmil-images/mine/3ra9) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | Descriptor: | Capsid protein, DNA (5'-D(P*CP*A)-3') | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | Deposit date: | 2011-03-27 | Release date: | 2011-09-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3RAA
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![BU of 3raa by Molmil](/molmil-images/mine/3raa) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | Descriptor: | ADENOSINE MONOPHOSPHATE, Capsid protein | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | Deposit date: | 2011-03-27 | Release date: | 2011-09-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3RA4
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![BU of 3ra4 by Molmil](/molmil-images/mine/3ra4) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | Descriptor: | Capsid protein, DNA (5'-D(*CP*A)-3') | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | Deposit date: | 2011-03-27 | Release date: | 2011-09-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3MH0
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![BU of 3mh0 by Molmil](/molmil-images/mine/3mh0) | Mutagenesis of p38 MAP Kinase eshtablishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state | Descriptor: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. | Deposit date: | 2010-04-07 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry, 46, 2007
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3MH3
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![BU of 3mh3 by Molmil](/molmil-images/mine/3mh3) | Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state | Descriptor: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. | Deposit date: | 2010-04-07 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry, 46, 2007
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3MH2
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![BU of 3mh2 by Molmil](/molmil-images/mine/3mh2) | Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state | Descriptor: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. | Deposit date: | 2010-04-07 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry, 46, 2007
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3HEC
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![BU of 3hec by Molmil](/molmil-images/mine/3hec) | P38 in complex with Imatinib | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Namboodiri, H.V, Karpusas, M. | Deposit date: | 2009-05-08 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry, 49, 2010
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3HEG
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![BU of 3heg by Molmil](/molmil-images/mine/3heg) | P38 in complex with Sorafenib | Descriptor: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Mitogen-activated protein kinase 14 | Authors: | Namboodiri, H.V, Karpusas, M. | Deposit date: | 2009-05-08 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry, 49, 2010
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7EHA
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![BU of 7eha by Molmil](/molmil-images/mine/7eha) | Crystal structure of the flagellar hook cap from Salmonella enterica serovar Typhimurium | Descriptor: | Basal-body rod modification protein FlgD | Authors: | Matsunami, H, Yoon, Y.-H, Imada, K, Namba, K, Samatey, F.A. | Deposit date: | 2021-03-29 | Release date: | 2021-11-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the bacterial flagellar hook cap provides insights into a hook assembly mechanism Commun Biol, 4, 2021
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7EH9
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![BU of 7eh9 by Molmil](/molmil-images/mine/7eh9) | Crystal structure of the flagellar hook cap fragment from Salmonella enterica serovar Typhimurium | Descriptor: | Basal-body rod modification protein FlgD | Authors: | Matsunami, H, Yoon, Y.-H, Imada, K, Namba, K, Samatey, F.A. | Deposit date: | 2021-03-29 | Release date: | 2021-11-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the bacterial flagellar hook cap provides insights into a hook assembly mechanism Commun Biol, 4, 2021
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8UTE
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![BU of 8ute by Molmil](/molmil-images/mine/8ute) | Structure of SARS-Cov2 3CLPro in complex with Compound 27 | Descriptor: | 1,2-ETHANEDIOL, 3C-like proteinase nsp5, methyl {(2S)-1-[(1S,3aR,6aS)-1-{[(2R,3S)-6,6-difluoro-2-hydroxy-1-(methylamino)-1-oxoheptan-3-yl]carbamoyl}hexahydrocyclopenta[c]pyrrol-2(1H)-yl]-3,3-dimethyl-1-oxobutan-2-yl}carbamate | Authors: | Krishnamurthy, H, Zhuang, N, Qiang, D, Wu, Y, Klein, D.J. | Deposit date: | 2023-10-31 | Release date: | 2024-03-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J.Med.Chem., 67, 2024
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3TEE
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![BU of 3tee by Molmil](/molmil-images/mine/3tee) | Crystal Structure of Salmonella FlgA in open form | Descriptor: | CHLORIDE ION, Flagella basal body P-ring formation protein flgA, GLYCEROL | Authors: | Matsunami, H, Samatey, F.A, Namba, K. | Deposit date: | 2011-08-12 | Release date: | 2012-08-15 | Last modified: | 2016-07-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural flexibility of the periplasmic protein, FlgA, regulates flagellar P-ring assembly in Salmonella enterica Sci Rep, 6, 2016
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5JXL
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![BU of 5jxl by Molmil](/molmil-images/mine/5jxl) | |
8UPV
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![BU of 8upv by Molmil](/molmil-images/mine/8upv) | Structure of SARS-Cov2 3CLPro in complex with Compound 33 | Descriptor: | 3C-like proteinase nsp5, methyl {(2S)-1-[(1S,3aR,6aS)-1-{[(2R,3S,6R)-6-fluoro-2-hydroxy-1-(methylamino)-1-oxoheptan-3-yl]carbamoyl}hexahydrocyclopenta[c]pyrrol-2(1H)-yl]-3,3-dimethyl-1-oxobutan-2-yl}carbamate | Authors: | Krishnamurthy, H, Zhuang, N, Qiang, D, Wu, Y, Klein, D.J. | Deposit date: | 2023-10-23 | Release date: | 2024-03-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J.Med.Chem., 67, 2024
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