1WQS
| Crystal structure of Norovirus 3C-like protease | Descriptor: | 3C-like protease, D(-)-TARTARIC ACID, L(+)-TARTARIC ACID, ... | Authors: | Nakamura, K, Someya, Y, Kumasaka, T, Tanaka, N. | Deposit date: | 2004-10-01 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A norovirus protease structure provides insights into active and substrate binding site integrity J.Virol., 79, 2005
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4DCN
| Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1 | Descriptor: | ADP-ribosylation factor-like protein 1, Arfaptin-2, MAGNESIUM ION, ... | Authors: | Nakamura, K, Xie, Y, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-01-18 | Release date: | 2012-06-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase J.Biol.Chem., 287, 2012
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7XY8
| Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN) | Descriptor: | Isoform 2 of Basigin, heavy chain, light chain | Authors: | Nakamura, K, Amano, M, Yoneda, K, Suzuki, M, Fukuchi, K. | Deposit date: | 2022-06-01 | Release date: | 2022-11-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals. J Oncol, 2022, 2022
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3SIC
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3HSB
| Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer | Descriptor: | Protein hfq, RNA (5'-R(*AP*GP*AP*GP*AP*GP*A)-3') | Authors: | Baba, S, Someya, T, Kumasaka, T, Kawai, G, Nakamura, K. | Deposit date: | 2009-06-10 | Release date: | 2010-06-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq Nucleic Acids Res., 40, 2012
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1EW0
| CRYSTAL STRUCTURE ANALYSIS OF THE SENSOR DOMAIN OF RMFIXL(FERROUS FORM) | Descriptor: | FIXL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y. | Deposit date: | 2000-04-21 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies J.MOL.BIOL., 301, 2000
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1D06
| STRUCTURAL BASIS OF DIMERIZATION AND SENSORY MECHANISMS OF OXYGEN-SENSING DOMAIN OF RHIZOBIUM MELILOTI FIXL DETERMINED AT 1.4A RESOLUTION | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, nitrogen fixation regulatory protein fixL | Authors: | Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y. | Deposit date: | 1999-09-09 | Release date: | 2000-03-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies J.MOL.BIOL., 301, 2000
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2TLD
| CRYSTAL STRUCTURE OF AN ENGINEERED SUBTILISIN INHIBITOR COMPLEXED WITH BOVINE TRYPSIN | Descriptor: | STREPTOMYCES SUBTILISIN INHIBITOR (SSI), TRYPSIN | Authors: | Mitsui, Y, Takeuchi, Y, Nonaka, T, Nakamura, K.T. | Deposit date: | 1991-09-16 | Release date: | 1992-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin. Proc.Natl.Acad.Sci.USA, 89, 1992
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1BOL
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7YRU
| ALK2 antibody complex | Descriptor: | Activin receptor type-1, antibody heavy chain, antibody light chain | Authors: | Kawaguchi, Y, Nakamura, K, Suzuki, M, Tsuji, S, Katagiri, T. | Deposit date: | 2022-08-10 | Release date: | 2023-05-17 | Last modified: | 2023-06-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders. Nat Commun, 14, 2023
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2SIC
| REFINED CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' AND STREPTOMYCES SUBTILISIN INHIBITOR AT 1.8 ANGSTROMS RESOLUTION | Descriptor: | CALCIUM ION, STREPTOMYCES SUBTILISIN INHIBITOR (SSI), SUBTILISIN BPN' | Authors: | Mitsui, Y, Takeuchi, Y, Hirono, S, Akagawa, H, Nakamura, K.T. | Deposit date: | 1991-04-01 | Release date: | 1993-04-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution. J.Mol.Biol., 221, 1991
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5SIC
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1RDS
| CRYSTAL STRUCTURE OF RIBONUCLEASE MS (AS RIBONUCLEASE T1 HOMOLOGUE) COMPLEXED WITH A GUANYLYL-3',5'-CYTIDINE ANALOGUE | Descriptor: | 2'-FLUOROGUANYLYL-(3'-5')-PHOSPHOCYTIDINE, RIBONUCLEASE MS | Authors: | Nonaka, T, Nakamura, K.T, Mitsui, Y. | Deposit date: | 1993-05-14 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of ribonuclease Ms (as a ribonuclease T1 homologue) complexed with a guanylyl-3',5'-cytidine analogue. Biochemistry, 32, 1993
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1DIX
| CRYSTAL STRUCTURE OF RNASE LE | Descriptor: | EXTRACELLULAR RIBONUCLEASE LE | Authors: | Tanaka, N, Nakamura, K.T. | Deposit date: | 1999-11-30 | Release date: | 2000-09-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of a plant ribonuclease, RNase LE. J.Mol.Biol., 298, 2000
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1WM1
| Crystal Structure of Prolyl Aminopeptidase, Complex with Pro-TBODA | Descriptor: | (5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)[(2R)-PYRROLIDIN-2-YL]METHANONE, Proline iminopeptidase | Authors: | Nakajima, Y, Inoue, T, Ito, K, Tozaka, T, Hatakeyama, S, Tanaka, N, Nakamura, K.T, Yoshimoto, T. | Deposit date: | 2004-07-01 | Release date: | 2004-07-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor ARCH.BIOCHEM.BIOPHYS., 416, 2003
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1RMS
| CRYSTAL STRUCTURES OF RIBONUCLEASE MS COMPLEXED WITH 3'-GUANYLIC ACID A GP*C ANALOGUE, 2'-DEOXY-2'-FLUOROGUANYLYL-3',5'-CYTIDINE | Descriptor: | GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE MS | Authors: | Nonaka, T, Mitsui, Y, Nakamura, K.T. | Deposit date: | 1991-12-02 | Release date: | 1992-07-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of ribonuclease Ms (as a ribonuclease T1 homologue) complexed with a guanylyl-3',5'-cytidine analogue. Biochemistry, 32, 1993
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6IUE
| DNA helical wire containing Hg(II) | Descriptor: | DNA (5'-D(*TP*TP*TP*GP*C)-3'), MERCURY (II) ION | Authors: | Ono, A, Kanazawa, H, Ito, H, Goto, M, Nakamura, K, Saneyoshi, H, Kondo, J. | Deposit date: | 2018-11-28 | Release date: | 2019-10-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | A Novel DNA Helical Wire Containing HgII-Mediated T:T and T:G Pairs. Angew.Chem.Int.Ed.Engl., 58, 2019
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1WDY
| Crystal structure of ribonuclease | Descriptor: | 2-5A-dependent ribonuclease, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE | Authors: | Tanaka, N, Nakanishi, M, Kusakabe, Y, Goto, Y, Kitade, Y, Nakamura, K.T. | Deposit date: | 2004-05-19 | Release date: | 2004-10-05 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L Embo J., 23, 2004
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1WRJ
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3VW8
| Crystal structure of human c-Met kinase domain with its inhibitor | Descriptor: | CHLORIDE ION, Hepatocyte growth factor receptor, N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide | Authors: | Matsumoto, S, Miyamoto, N, Hirayama, T, Oki, H, Okada, K, Tawada, M, Iwata, H, Miki, H, Nakamura, K, Hori, A, Imamura, S. | Deposit date: | 2012-08-08 | Release date: | 2013-08-14 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors. Bioorg.Med.Chem., 21, 2013
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1WTA
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1WOJ
| Crystal structure of human phosphodiesterase | Descriptor: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase, PHOSPHATE ION | Authors: | Sakamoto, Y, Tanaka, N, Ichimiya, T, Kurihara, T, Nakamura, K.T. | Deposit date: | 2004-08-19 | Release date: | 2005-03-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the catalytic fragment of human brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase J.Mol.Biol., 346, 2005
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2DLC
| Crystal structure of the ternary complex of yeast tyrosyl-tRNA synthetase | Descriptor: | MAGNESIUM ION, O-(ADENOSINE-5'-O-YL)-N-(L-TYROSYL)PHOSPHORAMIDATE, T-RNA (76-MER), ... | Authors: | Tsunoda, M, Kusakabe, Y, Tanaka, N, Nakamura, K.T. | Deposit date: | 2006-04-18 | Release date: | 2007-06-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms. Nucleic Acids Res., 35, 2007
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1V7Z
| creatininase-product complex | Descriptor: | MANGANESE (II) ION, N-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE, SULFATE ION, ... | Authors: | Yoshimoto, T, Tanaka, N, Kanada, N, Inoue, T, Nakajima, Y, Haratake, M, Nakamura, K.T, Xu, Y, Ito, K. | Deposit date: | 2003-12-26 | Release date: | 2004-01-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism J.Mol.Biol., 337, 2004
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1V8B
| Crystal structure of a hydrolase | Descriptor: | ADENOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, adenosylhomocysteinase | Authors: | Tanaka, N, Nakanishi, M, Kusakabe, Y, Shiraiwa, K, Kitade, Y, Nakamura, K.T. | Deposit date: | 2004-01-03 | Release date: | 2004-10-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of S-Adenosyl-l-Homocysteine Hydrolase from the Human Malaria Parasite Plasmodium falciparum J.Mol.Biol., 343, 2004
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