7YRU

ALK2 antibody complex

Summary for 7YRU

• Entry DOI: 10.2210/pdb7yru/pdb
• Descriptor: Activin receptor type-1, antibody heavy chain, antibody light chain, ... (4 entities in total)
• Functional Keywords: alk2, protein binding, transferase-immune system complex, immune system, transferase/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 59973.15

Authors

Kawaguchi, Y.,Nakamura, K.,Suzuki, M.,Tsuji, S.,Katagiri, T. (deposition date: 2022-08-10, release date: 2023-05-17, Last modification date: 2023-06-07)

• Primary citation: Katagiri, T.,Tsukamoto, S.,Kuratani, M.,Tsuji, S.,Nakamura, K.,Ohte, S.,Kawaguchi, Y.,Takaishi, K.; A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders.; Nat Commun, 14:2960-2960, 2023; PubMed: 37231012; DOI: 10.1038/s41467-023-38746-5

Experimental method

X-RAY DIFFRACTION (2.6 Å)