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PDB: 60 件
6J84
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Crystal structure of TleB with hydroxyl analog
分子名称: (2S)-2-hydroxy-N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-3-methylbutanamide, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE
著者Nakamura, H, Mori, T, Abe, I.
登録日2019-01-18
公開日2019-08-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis.
Nat.Chem.Biol., 15, 2019
1LAW
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STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY-FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core.
Biochemistry, 32, 1993
1LAV
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STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY-FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core.
Biochemistry, 32, 1993
1EW0
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CRYSTAL STRUCTURE ANALYSIS OF THE SENSOR DOMAIN OF RMFIXL(FERROUS FORM)
分子名称: FIXL, PROTOPORPHYRIN IX CONTAINING FE
著者Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y.
登録日2000-04-21
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies
J.MOL.BIOL., 301, 2000
1MBE
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1
分子名称: MYB PROTO-ONCOGENE PROTEIN
著者Ogata, K, Morikawa, S, Nakamura, H, Hojo, H, Yoshimura, S, Zhang, R, Aimoto, S, Ametani, Y, Hirata, Z, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-05-19
公開日1995-07-31
最終更新日2012-02-29
実験手法SOLUTION NMR
主引用文献Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBJ
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
分子名称: MYB PROTO-ONCOGENE PROTEIN
著者Ogata, K, Morikawa, S, Nakamura, H, Hojo, H, Yoshimura, S, Zhang, R, Aimoto, S, Ametani, Y, Hirata, Z, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-05-19
公開日1995-07-31
最終更新日2012-02-29
実験手法SOLUTION NMR
主引用文献Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBH
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2
分子名称: C-MYB
著者Ogata, K, Morikawa, S, Nakamura, H, Hojo, H, Yoshimura, S, Zhang, R, Aimoto, S, Ametani, Y, Hirata, Z, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-05-19
公開日1995-09-15
最終更新日2012-02-29
実験手法SOLUTION NMR
主引用文献Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBK
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
分子名称: MYB PROTO-ONCOGENE PROTEIN
著者Ogata, K, Morikawa, S, Nakamura, H, Hojo, H, Yoshimura, S, Zhang, R, Aimoto, S, Ametani, Y, Hirata, Z, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-05-19
公開日1995-07-31
最終更新日2012-02-29
実験手法SOLUTION NMR
主引用文献Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBF
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1
分子名称: MYB PROTO-ONCOGENE PROTEIN
著者Ogata, K, Morikawa, S, Nakamura, H, Hojo, H, Yoshimura, S, Zhang, R, Aimoto, S, Ametani, Y, Hirata, Z, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-05-19
公開日1995-07-31
最終更新日2012-02-29
実験手法SOLUTION NMR
主引用文献Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBG
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2
分子名称: MYB PROTO-ONCOGENE PROTEIN
著者Ogata, K, Morikawa, S, Nakamura, H, Hojo, H, Yoshimura, S, Zhang, R, Aimoto, S, Ametani, Y, Hirata, Z, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-05-19
公開日1995-07-31
最終更新日2012-02-29
実験手法SOLUTION NMR
主引用文献Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1D06
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STRUCTURAL BASIS OF DIMERIZATION AND SENSORY MECHANISMS OF OXYGEN-SENSING DOMAIN OF RHIZOBIUM MELILOTI FIXL DETERMINED AT 1.4A RESOLUTION
分子名称: PROTOPORPHYRIN IX CONTAINING FE, nitrogen fixation regulatory protein fixL
著者Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y.
登録日1999-09-09
公開日2000-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies
J.MOL.BIOL., 301, 2000
1MSE
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SOLUTION STRUCTURE OF A SPECIFIC DNA COMPLEX OF THE MYB DNA-BINDING DOMAIN WITH COOPERATIVE RECOGNITION HELICES
分子名称: C-Myb DNA-Binding Domain, DNA (5'-D(*AP*TP*GP*TP*GP*TP*GP*TP*CP*AP*GP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*AP*CP*TP*GP*AP*CP*AP*CP*AP*CP*AP*T)-3')
著者Ogata, K, Morikawa, S, Nakamura, H, Sekikawa, A, Inoue, T, Kanai, H, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-01-24
公開日1995-03-31
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices.
Cell(Cambridge,Mass.), 79, 1994
3ETA
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Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor
分子名称: 1-(3-{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea, insulin receptor, kinase domain
著者Patnaik, S, Stevens, K, Gerding, R, Deanda, F, Shotwell, B, Tang, J, Hamajima, T, Nakamura, H, Leesnitzer, A, Hassell, A, Shewchuk, L, Kumar, R, Lei, H, Chamberlain, S.
登録日2008-10-07
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.
Bioorg.Med.Chem.Lett., 19, 2009
1MSF
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SOLUTION STRUCTURE OF A SPECIFIC DNA COMPLEX OF THE MYB DNA-BINDING DOMAIN WITH COOPERATIVE RECOGNITION HELICES
分子名称: C-Myb DNA-Binding Domain, DNA (5'-D(*AP*TP*GP*TP*GP*TP*GP*TP*CP*AP*GP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*AP*CP*TP*GP*AP*CP*AP*CP*AP*CP*AP*T)-3')
著者Ogata, K, Morikawa, S, Nakamura, H, Sekikawa, A, Inoue, T, Kanai, H, Sarai, A, Ishii, S, Nishimura, Y.
登録日1995-01-24
公開日1995-03-31
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices.
Cell(Cambridge,Mass.), 79, 1994
2RN2
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STRUCTURAL DETAILS OF RIBONUCLEASE H FROM ESCHERICHIA COLI AS REFINED TO AN ATOMIC RESOLUTION
分子名称: RIBONUCLEASE H
著者Katayanagi, K, Miyagawa, M, Matsushima, M, Ishikawa, M, Kanaya, S, Nakamura, H, Ikehara, M, Matsuzaki, T, Morikawa, K.
登録日1992-04-15
公開日1993-10-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution.
J.Mol.Biol., 223, 1992
1GOB
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COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
1GOC
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COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
8XJ0
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Crystal structure of AmFab mutant - P40C/E165C (Light chain), G10C/P210C(Heavy chain)
分子名称: Adalimumab Fab Heavy chain, Adalimumab Fab Light chain
著者Senda, M, Yoshikawa, M, Nakamura, H, Ohkuri, T, Senda, T.
登録日2023-12-20
公開日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Stabilization of adalimumab Fab through the introduction of disulfide bonds between the variable and constant domains.
Biochem.Biophys.Res.Commun., 700, 2024
4YN8
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Crystal Structure of Response Regulator ChrA in Heme-Sensing Two Component System
分子名称: MAGNESIUM ION, Response regulator ChrA, SULFATE ION
著者Doi, A, Nakamura, H, Shiro, Y, Sugimoto, H.
登録日2015-03-09
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the response regulator ChrA in the haem-sensing two-component system of Corynebacterium diphtheriae.
Acta Crystallogr.,Sect.F, 71, 2015
1IDZ
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STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 STRUCTURES
分子名称: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
著者Furukawa, K, Oda, M, Nakamura, H.
登録日1996-08-15
公開日1996-12-23
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Proc.Natl.Acad.Sci.USA, 93, 1996
1IDY
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STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
著者Furukawa, K, Oda, M, Nakamura, H.
登録日1996-08-15
公開日1996-12-23
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Proc.Natl.Acad.Sci.USA, 93, 1996
1HNR
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H-NS (DNA-BINDING DOMAIN)
分子名称: H-NS
著者Shindo, H, Iwaki, T, Ieda, R, Kurumizaka, H, Ueguchi, C, Mizuno, T, Morikawa, S, Nakamura, H, Kuboniwa, H.
登録日1995-04-06
公開日1995-07-10
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli.
FEBS Lett., 360, 1995
1HNS
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H-NS (DNA-BINDING DOMAIN)
分子名称: H-NS
著者Shindo, H, Iwaki, T, Ieda, R, Kurumizaka, H, Ueguchi, C, Mizuno, T, Morikawa, S, Nakamura, H, Kuboniwa, H.
登録日1995-04-06
公開日1995-07-10
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli.
FEBS Lett., 360, 1995
1GOA
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COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
1NAO
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SOLUTION STRUCTURE OF AN RNA 2'-O-METHYLATED RNA DUPLEX CONTAINING AN RNA/DNA HYBRID SEGMENT AT THE CENTER, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: DNA/RNA (5'-R(*OMGP*OMUP*OMC)-D(P*AP*TP*CP*T)-R(P*OMCP*OMC)-3'), RNA (5'-R(*GP*GP*AP*GP*AP*UP*GP*AP*C)-3')
著者Nishizaki, T, Iwai, S, Ohtsuka, E, Nakamura, H.
登録日1996-03-29
公開日1997-01-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of an RNA.2'-O-methylated RNA hybrid duplex containing an RNA.DNA hybrid segment at the center.
Biochemistry, 36, 1997

 

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