1T3N
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![BU of 1t3n by Molmil](/molmil-images/mine/1t3n) | Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP | Descriptor: | MAGNESIUM ION, Primer DNA strand, THYMIDINE-5'-TRIPHOSPHATE, ... | Authors: | Nair, D.T, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K. | Deposit date: | 2004-04-27 | Release date: | 2004-07-20 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature, 430, 2004
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4R8T
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![BU of 4r8t by Molmil](/molmil-images/mine/4r8t) | Structure of JEV protease | Descriptor: | CHLORIDE ION, NS3, Serine protease subunit NS2B | Authors: | Nair, D.T, Weinert, T, Wang, M, Olieric, V. | Deposit date: | 2014-09-03 | Release date: | 2014-12-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.133 Å) | Cite: | Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
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1KC5
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![BU of 1kc5 by Molmil](/molmil-images/mine/1kc5) | CRYSTAL STRUCTURE OF ANTIBODY PC287 IN COMPLEX WITH PS1 PEPTIDE | Descriptor: | PC287 Immunoglobulin, PS1 peptide | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. | Deposit date: | 2001-11-07 | Release date: | 2002-07-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response. J.Immunol., 168, 2002
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1KCS
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![BU of 1kcs by Molmil](/molmil-images/mine/1kcs) | CRYSTAL STRUCTURE OF ANTIBODY PC282 IN COMPLEX WITH PS1 PEPTIDE | Descriptor: | PC282 IMMUNOGLOBULIN, PS1 peptide | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V.S, Salunke, D.M. | Deposit date: | 2001-11-11 | Release date: | 2002-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response. J.Immunol., 168, 2002
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1KCU
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![BU of 1kcu by Molmil](/molmil-images/mine/1kcu) | CRYSTAL STRUCTURE OF ANTIBODY PC287 | Descriptor: | PC287 IMMUNOGLOBULIN | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V.S, Salunke, D.M. | Deposit date: | 2001-11-11 | Release date: | 2002-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response. J.Immunol., 168, 2002
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1KCV
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![BU of 1kcv by Molmil](/molmil-images/mine/1kcv) | Crystal structure of antibody pc282 | Descriptor: | PC282 IMMUNOGLOBULIN | Authors: | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. | Deposit date: | 2001-11-11 | Release date: | 2002-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response. J.Immunol., 168, 2002
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5X9W
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![BU of 5x9w by Molmil](/molmil-images/mine/5x9w) | Mismatch Repair Protein | Descriptor: | DNA mismatch repair protein MutS, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Nair, D.T, Nirwal, S. | Deposit date: | 2017-03-10 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Mechanism of formation of a toroid around DNA by the mismatch sensor protein. Nucleic Acids Res., 46, 2018
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2FLP
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![BU of 2flp by Molmil](/molmil-images/mine/2flp) | Binary complex of the catalytic core of human DNA polymerase iota with DNA (template G) | Descriptor: | DNA polymerase iota, DNA primer strand, DNA template strand | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2006-01-06 | Release date: | 2006-12-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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2FLN
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![BU of 2fln by Molmil](/molmil-images/mine/2fln) | binary complex of catalytic core of human DNA polymerase iota with DNA (template A) | Descriptor: | DNA polymerase iota, DNA primer strand, DNA template strand | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2006-01-06 | Release date: | 2006-12-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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2FLL
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![BU of 2fll by Molmil](/molmil-images/mine/2fll) | Ternary complex of human DNA polymerase iota with DNA and dTTP | Descriptor: | DNA polymerase iota, DNA primer strand, DNA template strand, ... | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2006-01-06 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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1KCR
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![BU of 1kcr by Molmil](/molmil-images/mine/1kcr) | CRYSTAL STRUCTURE OF ANTIBODY PC283 IN COMPLEX WITH PS1 PEPTIDE | Descriptor: | PC283 IMMUNOGLOBULIN, PS1 peptide | Authors: | Nair, D.T, Singh, K, Sahu, N, Rao, K.V.S, Salunke, D.M. | Deposit date: | 2001-11-11 | Release date: | 2002-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition. J.Immunol., 165, 2000
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2DPJ
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![BU of 2dpj by Molmil](/molmil-images/mine/2dpj) | structure of hPoli with DNA and dTTP | Descriptor: | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2006-05-12 | Release date: | 2006-07-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat.Struct.Mol.Biol., 13, 2006
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2DPI
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![BU of 2dpi by Molmil](/molmil-images/mine/2dpi) | Ternary complex of hPoli with DNA and dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', ... | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2006-05-12 | Release date: | 2006-07-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat.Struct.Mol.Biol., 13, 2006
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2ALZ
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![BU of 2alz by Molmil](/molmil-images/mine/2alz) | Ternary Complex of hPoli with DNA and dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*T)-3', ... | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2005-08-08 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Human DNA Polymerase iota Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair. Structure, 13, 2005
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2AQ4
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![BU of 2aq4 by Molmil](/molmil-images/mine/2aq4) | Ternary complex of the catalytic core of REV1 with DNA and dCTP. | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*C)-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | Authors: | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | Deposit date: | 2005-08-17 | Release date: | 2005-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science, 309, 2005
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5C5J
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![BU of 5c5j by Molmil](/molmil-images/mine/5c5j) | Poymerase Nucleotide complex | Descriptor: | 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Kottur, J. | Deposit date: | 2015-06-20 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Reactive Oxygen Species Play an Important Role in the Bactericidal Activity of Quinolone Antibiotics Angew.Chem.Int.Ed.Engl., 55, 2016
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4IRD
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![BU of 4ird by Molmil](/molmil-images/mine/4ird) | Structure of Polymerase-DNA complex | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Nair, D.T, Sharma, A. | Deposit date: | 2013-01-14 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
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4IRC
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![BU of 4irc by Molmil](/molmil-images/mine/4irc) | Polymerase-DNA complex | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Nair, D.T, Sharma, A. | Deposit date: | 2013-01-14 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
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4IRK
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![BU of 4irk by Molmil](/molmil-images/mine/4irk) | structure of Polymerase-DNA complex, dna | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*A*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA (5'-D(*TP*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Nair, D.T, Sharma, A. | Deposit date: | 2013-01-14 | Release date: | 2013-04-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
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6JUR
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![BU of 6jur by Molmil](/molmil-images/mine/6jur) | MsDpo4-DNA complex 5 | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(*TP*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*A)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Johnson, M.K. | Deposit date: | 2019-04-15 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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6JUO
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![BU of 6juo by Molmil](/molmil-images/mine/6juo) | MsDpo4-DNA complex 4 | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*AP*GP*G)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Johnson, M.K. | Deposit date: | 2019-04-15 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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6JUS
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![BU of 6jus by Molmil](/molmil-images/mine/6jus) | MsDpo4-DNA complex 6 | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(*TP*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*AP*G)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Johnson, M.K. | Deposit date: | 2019-04-15 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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6JUL
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![BU of 6jul by Molmil](/molmil-images/mine/6jul) | MsDpo4-DNA complex 1 | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Johnson, M.K. | Deposit date: | 2019-04-15 | Release date: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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6JUM
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![BU of 6jum by Molmil](/molmil-images/mine/6jum) | MsDpo4-DNA complex 2 | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Johnson, M.J. | Deposit date: | 2019-04-15 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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6JUN
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![BU of 6jun by Molmil](/molmil-images/mine/6jun) | MsDpo4-DNA complex 3 | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | Authors: | Nair, D.T, Johnson, M.K. | Deposit date: | 2019-04-15 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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