6JUP
| Mutant PolIV-DNA incoming nucleotide complex | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(P*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Nair, D.T, Johnson, M.K. | 登録日 | 2019-04-15 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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6JUQ
| mutant PolIV-DNA incoming nucleotide complex 2 | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(P*CP*TP*GP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Nair, D.T, Johnson, M.K. | 登録日 | 2019-04-15 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | A polar filter in DNA polymerases prevents ribonucleotide incorporation. Nucleic Acids Res., 47, 2019
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3BJY
| Catalytic core of Rev1 in complex with DNA (modified template guanine) and incoming nucleotide | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*DAP*DTP*DCP*DCP*DTP*DCP*DCP*DCP*DCP*DTP*DAP*(DOC))-3'), DNA (5'-D(*DTP*DAP*DAP*(P)P*DGP*DTP*DAP*DGP*DGP*DGP*DGP*DAP*DGP*DGP*DAP*DT)-3'), ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2007-12-05 | 公開日 | 2008-10-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase Structure, 16, 2008
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4Q44
| Polymerase-Damaged DNA Complex | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*TP*CP*TP*AP*(RDG)P*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase IV, ... | 著者 | Nair, D.T, Kottur, J, Sharma, A. | 登録日 | 2014-04-13 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic Structure, 23, 2015
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4DEZ
| Structure of MsDpo4 | 分子名称: | DNA polymerase IV 1 | 著者 | Nair, D.T, Sharma, A. | 登録日 | 2012-01-22 | 公開日 | 2012-08-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The PAD region in the mycobacterial DinB homologue MsPolIV exhibits positional heterogeneity. Acta Crystallogr.,Sect.D, 68, 2012
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4H0E
| Crystal Structure of mutant ORR3 in complex with NTD of AraR | 分子名称: | 5'-D(*AP*AP*AP*TP*TP*TP*GP*TP*CP*CP*GP*TP*AP*CP*AP*TP*TP*TP*TP*AP*T)-3', 5'-D(*TP*AP*TP*AP*AP*AP*AP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*AP*AP*TP*T)-3', ACETATE ION, ... | 著者 | Nair, D.T, Jain, D. | 登録日 | 2012-09-08 | 公開日 | 2013-02-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.973 Å) | 主引用文献 | Spacing between core recognition motifs determines relative orientation of AraR monomers on bipartite operators. Nucleic Acids Res., 41, 2013
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3OSP
| Structure of rev1 | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | 著者 | Nair, D.T, Aggarwal, A.K. | 登録日 | 2010-09-09 | 公開日 | 2011-04-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. J.Mol.Biol., 406, 2011
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3G6V
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3G6Y
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3G6X
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6IG1
| DNA polymerase IV - DNA ternary complex 10 | 分子名称: | DIPHOSPHATE, DNA polymerase IV, DTN3, ... | 著者 | Kottur, J, Nair, D.T. | 登録日 | 2018-09-21 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction. Nucleic Acids Res., 46, 2018
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7WVL
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5D4S
| Crystal Structure of AraR(DBD) in complex with operator ORX1 | 分子名称: | Arabinose metabolism transcriptional repressor, DNA (5'-D(*AP*AP*AP*TP*AP*CP*AP*TP*AP*CP*GP*TP*AP*CP*AP*AP*AP*TP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*TP*AP*TP*GP*TP*AP*TP*T)-3') | 著者 | Jain, D, Narayanan, N, Nair, D.T. | 登録日 | 2015-08-08 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | 主引用文献 | Plasticity in Repressor-DNA Interactions Neutralizes Loss of Symmetry in Bipartite Operators. J.Biol.Chem., 291, 2016
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5D4R
| Crystal Structure of AraR(DBD) in complex with operator ORE1 | 分子名称: | Arabinose metabolism transcriptional repressor, DNA (5'-D(*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*TP*AP*CP*TP*AP*AP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*TP*AP*GP*TP*AP*CP*GP*TP*AP*CP*AP*AP*AP*TP*A)-3') | 著者 | Jain, D, Narayanan, N, Nair, D.T. | 登録日 | 2015-08-08 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Plasticity in Repressor-DNA Interactions Neutralizes Loss of Symmetry in Bipartite Operators. J.Biol.Chem., 291, 2016
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8JRB
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4R8U
| S-SAD structure of DINB-DNA Complex | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA, DNA polymerase IV, ... | 著者 | Kottur, J, Nair, D.T, Weinert, T, Oligeric, V, Wang, M. | 登録日 | 2014-09-03 | 公開日 | 2015-01-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination Nat.Methods, 12, 2015
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5YK4
| Mismatch Repair Protein | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein MutS | 著者 | Nirwal, S, Nair, D.T. | 登録日 | 2017-10-12 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Mechanism of formation of a toroid around DNA by the mismatch sensor protein. Nucleic Acids Res., 46, 2018
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1IIZ
| Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta | 分子名称: | LYSOZYME | 著者 | Jain, D, Nair, D.T, Swaminathan, G.J, Abraham, E.G, Nagaraju, J, Salunke, D.M. | 登録日 | 2001-04-24 | 公開日 | 2001-12-12 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the induced antibacterial protein from tasar silkworm, Antheraea mylitta. Implications to molecular evolution. J.Biol.Chem., 276, 2001
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6JBP
| Structure of MP-4 from Mucuna pruriens at 2.22 Angstroms | 分子名称: | Kunitz-type trypsin inhibitor-like 2 protein | 著者 | Jain, A, Shikhi, M, Kumar, A, Kumar, A, Nair, D.T, Salunke, D.M. | 登録日 | 2019-01-26 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.217 Å) | 主引用文献 | The structure of MP-4 from Mucuna pruriens at 2.22 angstrom resolution. Acta Crystallogr.,Sect.F, 76, 2020
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5DSS
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4IR9
| Polymerase-DNA complex | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(P*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Sharma, A, Nair, D.T. | 登録日 | 2013-01-14 | 公開日 | 2013-04-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
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4IR1
| Polymerase-DNA Complex | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | 著者 | Sharma, A, Nair, D.T. | 登録日 | 2013-01-14 | 公開日 | 2013-04-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
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6K0W
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3BSB
| Crystal Structure of Human Pumilio1 in Complex with CyclinB reverse RNA | 分子名称: | 5'-R(*UP*UP*UP*AP*AP*UP*GP*UP*U)-3', Pumilio homolog 1 | 著者 | Gupta, Y.K, Nair, D.T, Wharton, R.P, Aggarwal, A.K. | 登録日 | 2007-12-23 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. Structure, 16, 2008
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3BSX
| Crystal Structure of Human Pumilio 1 in complex with Puf5 RNA | 分子名称: | 5'-R(*UP*UP*GP*UP*AP*AP*UP*AP*UP*UP*A)-3', Pumilio homolog 1 | 著者 | Gupta, Y.K, Nair, D.T, Wharton, R.P, Aggarwal, A.K. | 登録日 | 2007-12-26 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. Structure, 16, 2008
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