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PDB: 17170 results

4WSM
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BU of 4wsm by Molmil
Complex of 70S ribosome with tRNA-Leu and mRNA with G-U mismatch in the first position in the A- and P-sites
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-28
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4X5I
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BU of 4x5i by Molmil
ecDHFR complexed with folate and NADP+ at 660 MPa
Descriptor: BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ...
Authors:Yamada, H, Watanabe, N, Nagae, T.
Deposit date:2014-12-05
Release date:2016-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-pressure protein crystal structure analysis of Escherichia coli dihydrofolate reductase complexed with folate and NADP.
Acta Crystallogr D Struct Biol, 74, 2018
7PH1
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BU of 7ph1 by Molmil
Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
Authors:Dimos, N, Leppkes, J, Koksch, B, Loll, B.
Deposit date:2021-08-16
Release date:2022-03-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment.
J.Phys.Chem.B, 126, 2022
4X2Z
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BU of 4x2z by Molmil
Structural view and substrate specificity of papain-like protease from Avian Infectious Bronchitis Virus
Descriptor: Nonstructural protein 3, ZINC ION
Authors:Kong, L, Shaw, N, Yan, L, Lou, Z, Rao, Z.
Deposit date:2014-11-27
Release date:2015-01-28
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural View and Substrate Specificity of Papain-like Protease from Avian Infectious Bronchitis Virus.
J.Biol.Chem., 290, 2015
4X3Z
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BU of 4x3z by Molmil
Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP and NAD
Descriptor: GLYCEROL, Inosine-5'-monophosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Osipiuk, J, MALTSEVA, N, KIM, Y, Mulligan, R, MAKOWSKA-GRZYSKA, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-12-02
Release date:2014-12-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP and NAD
to be published
7YXU
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BU of 7yxu by Molmil
Crystal structure of agonistic antibody 1618 fab domain bound to human 4-1BB.
Descriptor: MANGANESE (II) ION, Tumor necrosis factor receptor superfamily member 9, heavy chain of Fab, ...
Authors:Hakansson, M, Rose, N, Petersson, J, Enell Smith, K, Thorolfsson, M, von Schantz, L.
Deposit date:2022-02-16
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies.
Mol.Cancer Ther., 22, 2023
4WQR
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BU of 4wqr by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the first position in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-22
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4X8W
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BU of 4x8w by Molmil
dsRBD3 of Loquacious
Descriptor: GLYCEROL, Loquacious, isoform B
Authors:Jakob, L, Treiber, N, Treiber, T, Stotz, M, Meister, G.
Deposit date:2014-12-10
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.647 Å)
Cite:Structure of the dsRBD3 of Loquacious reveals features for dimerization and Dicer1-interaction
To Be Published
4WM5
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BU of 4wm5 by Molmil
High pressure protein crystallography of hen egg white lysozyme at 890 MPa
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Yamada, H, Nagae, T, Watanabe, N.
Deposit date:2014-10-08
Release date:2015-04-08
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-pressure protein crystallography of hen egg-white lysozyme
Acta Crystallogr.,Sect.D, 71, 2015
4X2T
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BU of 4x2t by Molmil
X-ray crystal structure of the orally available aminopeptidase inhibitor, Tosedostat, bound to the M17 Leucyl Aminopeptidase from P. falciparum
Descriptor: (2S)-({(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}amino)(phenyl)ethanoic acid, CARBONATE ION, M17 leucyl aminopeptidase, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2014-11-27
Release date:2015-02-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.729 Å)
Cite:X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17.
Proteins, 83, 2015
4WRO
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BU of 4wro by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-24
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
5HKZ
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BU of 5hkz by Molmil
Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (36-60, pY55) Refined to 1.8 A Resolution (P21 form)
Descriptor: E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2, SODIUM ION
Authors:Lovell, S, Battaile, K.P, Mehzabeen, N, Zhang, N, Cooper, A, Gao, P, Perez, R.P.
Deposit date:2016-01-14
Release date:2017-01-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (36-60, pY55) Refined to 1.8 A Resolution (P21 form)
To be published
4WR6
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BU of 4wr6 by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-23
Release date:2015-06-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WYP
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BU of 4wyp by Molmil
The crystal structure of the A109G mutant of RNase A in complex with 5'AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic
Authors:French, R.L, Gagne, D, Doucet, N, Simonovic, M.
Deposit date:2014-11-17
Release date:2015-11-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
2RD3
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BU of 2rd3 by Molmil
Crystal structure of TenA homologue (HP1287) from Helicobacter pylori
Descriptor: Transcriptional regulator
Authors:Barison, N, Cendron, L, Trento, A, Angelini, A, Zanotti, G.
Deposit date:2007-09-21
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural and functional characterization of HP1287 from Helicobacter pylori demonstrates it is a TenA homologue
To be Published
7PKW
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BU of 7pkw by Molmil
Crystal structure of VIRB8-like OrfG central and C-terminal domains of Streptococcus thermophilus ICESt3 (Gram positive conjugative type IV secretion system).
Descriptor: GLYCEROL, Putative transfer protein, SULFATE ION
Authors:Favier, F, Didierjean, C, Cappele, J, Douzi, B, Leblond-Bourget, N.
Deposit date:2021-08-27
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.835 Å)
Cite:Crystal structure of VIRB8-like OrfG central and C-terminal domains of Streptococcus thermophilus ICESt3 (Gram positive conjugative type IV secretion system).
To Be Published
4WT1
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BU of 4wt1 by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with A-A mismatch in the second position in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-29
Release date:2015-06-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WYZ
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BU of 4wyz by Molmil
The crystal structure of the A109G mutant of RNase A in complex with 3'UMP
Descriptor: 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic
Authors:French, R.L, Gagne, D, Doucet, N, Simonovic, M.
Deposit date:2014-11-18
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4WZO
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BU of 4wzo by Molmil
Complex of 70S ribosome with tRNA-fMet and mRNA
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-11-20
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WYN
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BU of 4wyn by Molmil
The crystal structure of the A109G mutant of RNase A
Descriptor: Ribonuclease pancreatic
Authors:French, R.L, Gagne, D, Doucet, N, Simonovic, M.
Deposit date:2014-11-17
Release date:2015-11-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4X5F
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BU of 4x5f by Molmil
ecDHFR complexed with folate and NADP+ at 0.1 MPa
Descriptor: BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ...
Authors:Yamada, H, Watanabe, N, Nagae, T.
Deposit date:2014-12-05
Release date:2016-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High-pressure protein crystal structure analysis of Escherichia coli dihydrofolate reductase complexed with folate and NADP.
Acta Crystallogr D Struct Biol, 74, 2018
4WWL
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BU of 4wwl by Molmil
E. coli 5'-nucleotidase mutant I521C labeled with MTSL (intermediate form)
Descriptor: CARBONATE ION, GLYCEROL, Protein UshA, ...
Authors:Krug, U, Paithankar, K.S, Schultz-Heienbrok, R, Strater, N.
Deposit date:2014-11-11
Release date:2014-11-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:E. coli 5'-nucleotidase mutant I521C labeled with MTSL (intermediate form)
To Be Published
4X6Y
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BU of 4x6y by Molmil
Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
Descriptor: 4-phenoxy-N-[(1S,2R)-2-phenylcyclopropyl]piperidine-1-carboxamide, Bifunctional epoxide hydrolase 2
Authors:Chiyo, N, Takai, K, Ishii, T.
Deposit date:2014-12-09
Release date:2015-04-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
4WZQ
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BU of 4wzq by Molmil
Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA
Descriptor: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
5HKX
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BU of 5hkx by Molmil
Crystal Structure of c-Cbl TKBD-RING domains (Y371E mutant) Refined to 1.85 A Resolution
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase CBL, SODIUM ION, ...
Authors:Lovell, S, Battaile, K.P, Mehzabeen, N, Zhang, N, Cooper, A, Gao, P, Perez, R.P.
Deposit date:2016-01-14
Release date:2017-01-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of c-Cbl TKBD-RING domains (Y371E mutant) Refined to 1.85 A Resolution
To be published

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