4X2Z

Structural view and substrate specificity of papain-like protease from Avian Infectious Bronchitis Virus

Summary for 4X2Z

• Entry DOI: 10.2210/pdb4x2z/pdb
• Descriptor: Nonstructural protein 3, ZINC ION (3 entities in total)
• Functional Keywords: plpro, de-ubiquitination, ibv, coronavirus, hydrolase
• Biological source: Avian infectious bronchitis virus (IBV)
• Cellular location: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6Y1
• Total number of polymer chains: 1
• Total formula weight: 36119.06

Authors

Kong, L.,Shaw, N.,Yan, L.,Lou, Z.,Rao, Z. (deposition date: 2014-11-27, release date: 2015-01-28, Last modification date: 2015-04-01)

• Primary citation: Kong, L.,Shaw, N.,Yan, L.,Lou, Z.,Rao, Z.; Structural View and Substrate Specificity of Papain-like Protease from Avian Infectious Bronchitis Virus.; J.Biol.Chem., 290:7160-7168, 2015; PubMed: 25609249; DOI: 10.1074/jbc.M114.628636

Experimental method

X-RAY DIFFRACTION (2.15 Å)