2L3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l3h by Molmil](/molmil-images/mine/2l3h) | NMR Structure in a Membrane Environment Reveals Putative Amyloidogenic Regions of the SEVI Precursor Peptide PAP248-286 | Descriptor: | Prostatic acid phosphatase | Authors: | Ramamoorthy, A, Nanga, R, Brender, J, Vivekanandan, S, Popovych, N. | Deposit date: | 2010-09-13 | Release date: | 2010-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286). J.Am.Chem.Soc., 131, 2009
|
|
2LAZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2laz by Molmil](/molmil-images/mine/2laz) | Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
|
|
2LER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ler by Molmil](/molmil-images/mine/2ler) | Conotoxin pc16a | Descriptor: | Conotoxin pc16a | Authors: | Dyubankova, N, Lescrinier, E, Van Der Haegen, A, Peigneur, S, Tytgat, J. | Deposit date: | 2011-06-22 | Release date: | 2012-04-11 | Last modified: | 2012-04-18 | Method: | SOLUTION NMR | Cite: | Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity. Peptides, 34, 2012
|
|
6QYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qyn by Molmil](/molmil-images/mine/6qyn) | Structure of MBP-Mcl-1 in complex with compound 10d | Descriptor: | (2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. | Deposit date: | 2019-03-09 | Release date: | 2019-08-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
|
|
6QZQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qzq by Molmil](/molmil-images/mine/6qzq) | |
4OEM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oem by Molmil](/molmil-images/mine/4oem) | Crystal structure of Cathepsin C in complex with dipeptide substrates | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Zhao, B, Smallwood, A, Concha, N. | Deposit date: | 2014-01-13 | Release date: | 2015-03-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry, 51, 2012
|
|
6QN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qn7 by Molmil](/molmil-images/mine/6qn7) | Structure of bovine anti-RSV hybrid Fab B4HC-B13LC | Descriptor: | Heavy chain of bovine anti-RSV B4, Light chain of bovine anti-RSV B13 | Authors: | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | Deposit date: | 2019-02-10 | Release date: | 2019-05-29 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus. Mol.Immunol., 112, 2019
|
|
6QNV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qnv by Molmil](/molmil-images/mine/6qnv) | Fibrinogen-like globe domain of Human Tenascin-C | Descriptor: | Tenascin | Authors: | Coker, J.A, Bezerra, G.A, Bradshaw, W.J, Zhang, M, Yosaatmadja, Y, Fernandez-Cid, A, Shrestha, L, Burgess-Brown, N, Gileadi, O, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | Deposit date: | 2019-02-12 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Fibrinogen-like globe domain of Human Tenascin-C To Be Published
|
|
6QOY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qoy by Molmil](/molmil-images/mine/6qoy) | Crystal structure of L1 protease Lysobacter sp. XL1 in complex with AEBSF | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, 4-(2-azanylethyl)benzenesulfonic acid, CHLORIDE ION, ... | Authors: | Gabdulkhakov, A, Tishchenko, S, Kudryakova, I, Afoshin, A, Vasilyeva, N. | Deposit date: | 2019-02-13 | Release date: | 2019-12-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Serine bacteriolytic protease L1 of Lysobacter sp. XL1 complexed with protease inhibitor AEBSF: features of interaction Process Biochem, 2019
|
|
6QPH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qph by Molmil](/molmil-images/mine/6qph) | Dunaliella minimal PSI complex | Descriptor: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | Authors: | Klaiman, D, Caspy, I, Nelson, N. | Deposit date: | 2019-02-14 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure of a minimal photosystem I from the green alga Dunaliella salina. Nat.Plants, 6, 2020
|
|
2L82
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l82 by Molmil](/molmil-images/mine/2l82) | Solution NMR Structure of de novo designed protein, P-loop NTPase fold, Northeast Structural Genomics Consortium Target OR32 | Descriptor: | DESIGNED PROTEIN OR32 | Authors: | Liu, G, Koga, N, Koga, R, Xiao, R, Hamilton, K, Janjua, H, Tong, S, Acton, T.B, Everett, J, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-12-31 | Release date: | 2011-02-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Northeast Structural Genomics Consortium Target OR32 To be Published
|
|
2LC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lc5 by Molmil](/molmil-images/mine/2lc5) | Calmodulin-like Protein from Entamoeba histolytica: Solution Structure and Calcium-Binding Properties of a Partially Folded Protein | Descriptor: | CALCIUM ION, Calmodulin, putative | Authors: | Rout, A.K, Padhan, N, Barnwal, R.P, Bhattacharya, A, Chary, K.V. | Deposit date: | 2011-04-23 | Release date: | 2011-06-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Calmodulin like protein from Entamoeba histolytica: solution structure and calcium binding properties of a partially folded protein. Biochemistry, 50, 2010
|
|
6QT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qt9 by Molmil](/molmil-images/mine/6qt9) | Cryo-EM structure of SH1 full particle. | Descriptor: | ORF 24, ORF 25, ORF 31, ... | Authors: | De Colibus, L, Roine, E, Walter, T.S, Ilca, S.L, Wang, X, Wang, N, Roseman, A.M, Bamford, D, Huiskonen, J.T, Stuart, D.I. | Deposit date: | 2019-02-22 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Assembly of complex viruses exemplified by a halophilic euryarchaeal virus. Nat Commun, 10, 2019
|
|
6QYO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qyo by Molmil](/molmil-images/mine/6qyo) | Structure of MBP-Mcl-1 in complex with compound 18a | Descriptor: | (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. | Deposit date: | 2019-03-09 | Release date: | 2019-08-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
|
|
2LAW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2law by Molmil](/molmil-images/mine/2law) | Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
|
|
6QRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qro by Molmil](/molmil-images/mine/6qro) | Crystal structure of Tannerella forsythia glutaminyl cyclase | Descriptor: | Glutamine cyclotransferase, SULFATE ION, ZINC ION | Authors: | Linnert, M, Piechotta, A, Parthier, C, Taudte, N, Kolenko, P, Rahfeld, J, Potempa, J, Stubbs, M.T. | Deposit date: | 2019-02-19 | Release date: | 2019-03-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis. J.Biol.Chem., 296, 2021
|
|
6QUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qua by Molmil](/molmil-images/mine/6qua) | The complex structure of hsRosR-SG (vng0258/RosR-SG) | Descriptor: | DNA (28-MER), MANGANESE (II) ION, SULFATE ION, ... | Authors: | Shaanan, B, Kutnowski, N. | Deposit date: | 2019-02-27 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.681 Å) | Cite: | Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein hsRosR. Nucleic Acids Res., 47, 2019
|
|
2LRH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lrh by Molmil](/molmil-images/mine/2lrh) | Solution NMR structure of de novo designed protein, p-loop ntpase fold, Northeast Structural Genomics Consortium target or137 | Descriptor: | De novo designed protein | Authors: | Liu, G, Koga, N, Koga, R, Xiao, R, Lee, H, Janjua, H, Kohan, E, Acton, T.B, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-03-30 | Release date: | 2012-07-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of de novo designed protein, p-loop ntpase fold, Northeast Structural Genomics Consortium target or137 To be Published
|
|
2L87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l87 by Molmil](/molmil-images/mine/2l87) | The 27-residue N-terminus CCR5-peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide | Descriptor: | C-C chemokine receptor type 5 | Authors: | Schnur, E, Noah, E, Ayzenshtat, I, Sargsyan, H, Inui, T, Ding, F.X, Arshava, B, Sagi, Y, Kessler, N, Levy, R, Scherf, T, Naider, F, Anglister, J. | Deposit date: | 2011-01-06 | Release date: | 2011-07-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic Peptide. J.Mol.Biol., 410, 2011
|
|
2L7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l7n by Molmil](/molmil-images/mine/2l7n) | Solution Structure of the R5 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Barsukov, I.L, Roberts, G.C.K, Critchley, D.R. | Deposit date: | 2010-12-14 | Release date: | 2011-12-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover. J.Biol.Chem., 288, 2013
|
|
6QN8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qn8 by Molmil](/molmil-images/mine/6qn8) | Structure of bovine anti-RSV Fab B13 | Descriptor: | CHLORIDE ION, Heavy chain of bovine anti-RSV B13 Fab, Light chain of bovine anti-RSV Fab B13 | Authors: | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | Deposit date: | 2019-02-10 | Release date: | 2019-05-29 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus. Mol.Immunol., 112, 2019
|
|
7NFY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nfy by Molmil](/molmil-images/mine/7nfy) | P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ... | Authors: | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | Deposit date: | 2021-02-08 | Release date: | 2021-02-24 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
|
|
7NG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ng5 by Molmil](/molmil-images/mine/7ng5) | P1c-state of wild type human mitochondrial LONP1 protease with bound substrate protein in presence of ATP/ADP mix | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | Authors: | Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P. | Deposit date: | 2021-02-08 | Release date: | 2021-02-24 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
|
|
2LB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lb0 by Molmil](/molmil-images/mine/2lb0) | Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
|
|
6QZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qzt by Molmil](/molmil-images/mine/6qzt) | |