2L3H

NMR Structure in a Membrane Environment Reveals Putative Amyloidogenic Regions of the SEVI Precursor Peptide PAP248-286

Summary for 2L3H

Entry DOI	10.2210/pdb2l3h/pdb
NMR Information	BMRB: 17193
Descriptor	Prostatic acid phosphatase (1 entity in total)
Functional Keywords	sevi, pap248-286, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Secreted (By similarity). Isoform 2: Lysosome membrane; Single-pass type I membrane protein: P15309
Total number of polymer chains	1
Total formula weight	4561.46
Authors	Ramamoorthy, A.,Nanga, R.,Brender, J.,Vivekanandan, S.,Popovych, N. (deposition date: 2010-09-13, release date: 2010-10-06, Last modification date: 2024-05-01)
Primary citation	Nanga, R.P.,Brender, J.R.,Vivekanandan, S.,Popovych, N.,Ramamoorthy, A. NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286). J.Am.Chem.Soc., 131:17972-17979, 2009 Cited by PubMed: 19995078 DOI: 10.1021/ja908170s PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation