2BQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bqz by Molmil](/molmil-images/mine/2bqz) | Crystal structure of a ternary complex of the human histone methyltransferase Pr-SET7 (also known as SET8) | Descriptor: | HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE, SET8 PROTEIN | Authors: | Xiao, B, Jing, C, Kelly, G, Walker, P.A, Muskett, F.W, Frenkiel, T.A, Martin, S.R, Sarma, K, Reinberg, D, Gamblin, S.J, Wilson, J.R. | Deposit date: | 2005-04-28 | Release date: | 2005-06-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Specificity and Mechanism of the Histone Methyltransferase Pr-Set7 Genes Dev., 19, 2005
|
|
1SD4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sd4 by Molmil](/molmil-images/mine/1sd4) | Crystal Structure of a SeMet derivative of BlaI at 2.0 A | Descriptor: | PENICILLINASE REPRESSOR, SULFATE ION | Authors: | Safo, M.K, Zhao, Q, Musayev, F.N, Robinson, H, Scarsdale, N, Archer, G.L. | Deposit date: | 2004-02-13 | Release date: | 2004-08-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons J.Bacteriol., 187, 2005
|
|
1RV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rv4 by Molmil](/molmil-images/mine/1rv4) | E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ... | Authors: | Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V. | Deposit date: | 2003-12-12 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism. Biochemistry, 43, 2004
|
|
1G79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g79 by Molmil](/molmil-images/mine/1g79) | X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION | Descriptor: | BETA-MERCAPTOETHANOL, FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, ... | Authors: | Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V. | Deposit date: | 2000-11-09 | Release date: | 2000-11-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution. J.Mol.Biol., 310, 2001
|
|
1RVY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rvy by Molmil](/molmil-images/mine/1rvy) | E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE, COMPLEX WITH GLYCINE | Descriptor: | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V. | Deposit date: | 2003-12-15 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism. Biochemistry, 43, 2004
|
|
1RV3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rv3 by Molmil](/molmil-images/mine/1rv3) | E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE, COMPLEX WITH GLYCINE | Descriptor: | GLYCINE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Szebenyi, D.M, Musayev, F.N, di Salvo, M.L, Safo, M.K, Schirch, V. | Deposit date: | 2003-12-12 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism. Biochemistry, 43, 2004
|
|
1G76
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g76 by Molmil](/molmil-images/mine/1g76) | X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION | Descriptor: | FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V. | Deposit date: | 2000-11-09 | Release date: | 2000-11-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution. J.Mol.Biol., 310, 2001
|
|
1G78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g78 by Molmil](/molmil-images/mine/1g78) | X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION | Descriptor: | FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V. | Deposit date: | 2000-11-09 | Release date: | 2000-11-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution. J.Mol.Biol., 310, 2001
|
|
3TPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tpz by Molmil](/molmil-images/mine/3tpz) | |
1J5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j5i by Molmil](/molmil-images/mine/1j5i) | Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore | Descriptor: | 2-HYDROXY-7-METHOXY-5-METHYL-NAPHTHALENE-1-CARBOXYLIC ACID MESO-2,5-DIHYDROXY-CYCLOPENT-3-ENYL ESTER, PROTEIN (Apo-Neocarzinostatin) | Authors: | Urbaniak, M.D, Muskett, F.W, Finucane, M.D, Caddick, S, Woolfson, D.N. | Deposit date: | 2002-05-02 | Release date: | 2002-09-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore Biochemistry, 41, 2002
|
|
1G77
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g77 by Molmil](/molmil-images/mine/1g77) | X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5`-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION | Descriptor: | FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V. | Deposit date: | 2000-11-09 | Release date: | 2000-11-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution. J.Mol.Biol., 310, 2001
|
|
1F4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f4j by Molmil](/molmil-images/mine/1f4j) | STRUCTURE OF TETRAGONAL CRYSTALS OF HUMAN ERYTHROCYTE CATALASE | Descriptor: | CATALASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Safo, M.K, Musayev, F.N, Wu, S.H, Abraham, D.J, Ko, T.P. | Deposit date: | 2000-06-07 | Release date: | 2000-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of tetragonal crystals of human erythrocyte catalase. Acta Crystallogr.,Sect.D, 57, 2001
|
|
1H8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h8b by Molmil](/molmil-images/mine/1h8b) | EF-hands 3,4 from alpha-actinin / Z-repeat 7 from titin | Descriptor: | ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN | Authors: | Atkinson, R.A, Joseph, C, Kelly, G, Muskett, F.W, Frenkiel, T.A, Nietlispach, D, Pastore, A. | Deposit date: | 2001-02-01 | Release date: | 2001-08-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex Nat.Struct.Biol., 8, 2001
|
|
1WA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wa8 by Molmil](/molmil-images/mine/1wa8) | Solution Structure of the CFP-10.ESAT-6 Complex. Major Virulence Determinants of Pathogenic Mycobacteria | Descriptor: | 6 KDA EARLY SECRETORY ANTIGENIC TARGET (ESAT-6), ESAT-6 LIKE PROTEIN ESXB | Authors: | Renshaw, P.S, Lightbody, K.L, Veverka, V, Muskett, F.W, Kelly, G, Frenkiel, T.A, Gordon, S.V, Hewinson, R.G, Burke, B, Norman, J, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-10-25 | Release date: | 2005-06-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6 Embo J., 24, 2005
|
|
2DDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ddo by Molmil](/molmil-images/mine/2ddo) | Crystal Structure of Pyridoxal Kinase from the Escherichia coli pdxK gene at 2.6 A resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Safo, M.K, Musayev, F.N, di Salvo, M.L, Hunt, S, Claude, J.B, Schirch, V. | Deposit date: | 2006-02-02 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases. J.Bacteriol., 188, 2006
|
|
2M2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m2d by Molmil](/molmil-images/mine/2m2d) | Human programmed cell death 1 receptor | Descriptor: | Programmed cell death protein 1 | Authors: | Veverka, V, Cheng, X, Waters, L.C, Muskett, F.W, Morgan, S, Lesley, A, Griffiths, M, Stubberfield, C, Griffin, R, Henry, A.J, Robinson, M.K, Jansson, A, Ladbury, J.E, Ikemizu, S, Davis, S.J, Carr, M.D. | Deposit date: | 2012-12-18 | Release date: | 2013-02-27 | Last modified: | 2013-05-15 | Method: | SOLUTION NMR | Cite: | Structure and interactions of the human programmed cell death 1 receptor. J.Biol.Chem., 288, 2013
|
|
2DDM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ddm by Molmil](/molmil-images/mine/2ddm) | Crystal Structure of Pyridoxal Kinase from the Escherichia coli PdxK gene at 2.1 A resolution | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pyridoxine kinase | Authors: | Safo, M.K, Musayev, F.N, di Salvo, M.L, Hunt, S, Claude, J.B, Schirch, V. | Deposit date: | 2006-02-02 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases. J.Bacteriol., 188, 2006
|
|
1E9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e9t by Molmil](/molmil-images/mine/1e9t) | High resolution solution structure of human intestinal trefoil factor | Descriptor: | INTESTINAL TREFOIL FACTOR | Authors: | Lemercinier, X, Muskett, F, Cheeseman, B, McIntosh, P, Carr, M. | Deposit date: | 2000-10-26 | Release date: | 2000-12-08 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | High-Resolution Solution Structure of Human Intestinal Trefoil Factor and Functional Insights from Detailed Structural Comparisons with the Other Members of the Trefoil Family of Mammalian Cell Motility Factors Biochemistry, 40, 2001
|
|
3R5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r5i by Molmil](/molmil-images/mine/3r5i) | Crystal structure of liganded Hemoglobin complexed with a potent Antisickling agent, INN-312 | Descriptor: | 5-methoxy-2-(pyridin-3-ylmethoxy)benzaldehyde, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Safo, M.K, Musayev, F.N, Safo, R.P, Daniels, D, Eseonu, D.N, Parra, J. | Deposit date: | 2011-03-18 | Release date: | 2011-04-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and in Vitro Chracterization of Pyridyl Derivatives of Benzaldehydes : Highly Potent Antisickling Agents To be Published
|
|
1XSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xsd by Molmil](/molmil-images/mine/1xsd) | Crystal structure of the BlaI repressor in complex with DNA | Descriptor: | 5'-D(P*TP*AP*CP*TP*AP*CP*AP*TP*AP*TP*GP*TP*AP*GP*TP*A)-3', penicillinase repressor | Authors: | Safo, M.K, Ko, T.-P, Musayev, F.N, Zhao, Q, Robinson, H, Scarsdale, N, Wang, A.H.-J, Archer, G.L. | Deposit date: | 2004-10-19 | Release date: | 2005-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons J.Bacteriol., 187, 2005
|
|
2EFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2eft by Molmil](/molmil-images/mine/2eft) | Methanethiol-CYS 112 inhibition complex of E. coli ketoacyl synthase III (FABH) and Coenzyme A (high concentration (1.7mM) soak) | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, COENZYME A, METHANETHIOL, ... | Authors: | Alhamadsheh, M.M, Musayev, F, Komissarov, A.A, Sachdeva, S, Wright, H.T, Scarsdale, N, Florova, G, Reynolds, K.A. | Deposit date: | 2007-02-24 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Alkyl-CoA Disulfides as Inhibitors and Mechanistic Probes for FabH Enzymes Chem.Biol., 14, 2007
|
|
2KH2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kh2 by Molmil](/molmil-images/mine/2kh2) | Solution structure of a scFv-IL-1B complex | Descriptor: | Interleukin-1 beta, scFv | Authors: | Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D. | Deposit date: | 2009-03-23 | Release date: | 2009-09-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development. J.Biol.Chem., 284, 2009
|
|
2K8P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k8p by Molmil](/molmil-images/mine/2k8p) | Characterisation of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation | Descriptor: | Sclerostin | Authors: | Veverka, V, Henry, A.J, Slocombe, P.M, Ventom, A, Mulloy, B, Muskett, F.W, Muzylak, M, Greenslade, K, Moore, A, Zhang, L, Gong, J, Qian, X, Paszty, C, Taylor, R.J, Robinson, M.K, Carr, M.D. | Deposit date: | 2008-09-18 | Release date: | 2009-02-17 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Characterization of the Structural Features and Interactions of Sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation J.Biol.Chem., 284, 2009
|
|
4EN4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4en4 by Molmil](/molmil-images/mine/4en4) | Crystal Structure of the Ternary Human PL Kinase-Ginkgotoxin-MgATP Complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Safo, M.K, Musayev, F.N, Gandhi, A.K. | Deposit date: | 2012-04-12 | Release date: | 2012-05-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. Plos One, 7, 2012
|
|
4EOH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eoh by Molmil](/molmil-images/mine/4eoh) | Crystal Structure of Human PL Kinase with bound Theophylline | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pyridoxal Kinase, SODIUM ION, ... | Authors: | Safo, M.K, Gandhi, A.K, Musayev, F.N. | Deposit date: | 2012-04-14 | Release date: | 2012-05-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. Plos One, 7, 2012
|
|