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PDB: 17 件
2NWG
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Structure of CXCL12:heparin disaccharide complex
分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1
著者Murphy, J.W, Cho, Y, Lolis, E.
登録日2006-11-14
公開日2007-02-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin
J.Biol.Chem., 282, 2007
3GV3
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BU of 3gv3 by Molmil
CXCL12 (SDF) in trigonal space group
分子名称: CXCL12 protein
著者Murphy, J.W, Crichlow, G, Lolis, E.
登録日2009-03-30
公開日2010-01-26
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family.
Proteins, 78, 2009
3HP3
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Crystal structure of CXCL12
分子名称: CXCL12 protein, GOLD ION
著者Murphy, J.W, Lolis, E, Xiong, Y, Yuan, H, Crichlow, G.
登録日2009-06-03
公開日2010-01-26
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family
Proteins, 78, 2009
7MRU
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BU of 7mru by Molmil
Crystal structure of S62A MIF2 mutant
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-dopachrome decarboxylase
著者Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E.
登録日2021-05-09
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
7MW7
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BU of 7mw7 by Molmil
Crystal structure of P1G mutant of D-dopachrome tautomerase
分子名称: D-dopachrome decarboxylase, SODIUM ION, SULFATE ION
著者Manjula, R, Murphy, E.L, Murphy, J.W, Lolis, E.
登録日2021-05-15
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
7MSE
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High-resolution crystal structure of hMIF2 with tartrate at the active site
分子名称: D-dopachrome decarboxylase, L(+)-TARTARIC ACID
著者Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E.
登録日2021-05-11
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
7MRV
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F100A mutant structure of MIF2 (D-DT)
分子名称: D-dopachrome decarboxylase, SULFATE ION
著者Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E.
登録日2021-05-09
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
5KVY
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CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG
分子名称: CHLORIDE ION, DNA (30-MER), Poly(U)-binding-splicing factor PUF60
著者Hsiao, H.-H, Crichlow, G.V, Albright, R.A, Murphy, J.W, Lolis, E.J, Braddock, D.T.
登録日2016-07-15
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
7JNY
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Crystal structure of CXCL13
分子名称: C-X-C motif chemokine 13
著者Rosenberg Jr, E.M, Rajasekaran, D, Murphy, J.W, Pantouris, G, Lolis, E.J.
登録日2020-08-05
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.
Acta Crystallogr D Struct Biol, 76, 2020
3MZG
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Crystal structure of a human prolactin receptor antagonist in complex with the extracellular domain of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-05-12
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3N06
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BU of 3n06 by Molmil
A mutant human Prolactin receptor antagonist H27A in complex with the extracellular domain of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-05-13
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3N0P
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A mutant human Prolactin receptor antagonist H30A in complex with the extracellular domain of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-05-14
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCE
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BU of 3nce by Molmil
A mutant human Prolactin receptor antagonist H27A in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCB
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A mutant human Prolactin receptor antagonist H180A in complex with the extracellular domain of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCF
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BU of 3ncf by Molmil
A mutant human Prolactin receptor antagonist H30A in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
4FQN
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Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD)
分子名称: Malcavernin
著者Fisher, O.S, Zhang, R, Li, X, Murphy, J.W, Boggon, T.J.
登録日2012-06-25
公開日2012-12-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus.
Febs Lett., 587, 2013
3NCC
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BU of 3ncc by Molmil
A human Prolactin receptor antagonist in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010

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