5OTX
 
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5OTV
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5OTU
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5OTT
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5OTW
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6ZQQ
 | | Structure of the Pmt3-MIR domain with bound ligands | | 分子名称: | GLYCEROL, PMT3 isoform 1 | | 著者 | Wild, K, Chiapparino, A, Hackmann, Y, Mortensen, S, Sinning, I. | | 登録日 | 2020-07-10 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Functional implications of MIR domains in protein O -mannosylation.
Elife, 9, 2020
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8CQS
 | | Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_0217) | | 分子名称: | FLAVIN MONONUCLEOTIDE, Nitroreductase-like protein, PHOSPHATE ION | | 著者 | Blaha, J, Gratzl, S, Mortensen, S.A, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | | 登録日 | 2023-03-07 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron
To Be Published
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6ZH3
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8OXR
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8OVU
 | | Human titin immunoglobulin-like 21 domain | | 分子名称: | MAGNESIUM ION, Titin | | 著者 | Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M. | | 登録日 | 2023-04-26 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
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8P35
 | | Mutant human titin immunoglobulin-like 21 domain - C3575S | | 分子名称: | Titin | | 著者 | Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M. | | 登録日 | 2023-05-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
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1NYX
 | | Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist | | 分子名称: | (2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID, peroxisome proliferator activated receptor gamma | | 著者 | Ebdrup, S, Pettersson, I, Rasmussen, H.B, Deussen, H.-J, Frost Jensen, A, Mortensen, S.B, Fleckner, J, Pridal, L, Nygaard, L, Sauerberg, P. | | 登録日 | 2003-02-14 | | 公開日 | 2003-07-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar
J.MED.CHEM., 46, 2003
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7B9F
 | | Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | | 分子名称: | EccB5, EccC5, EccD5, ... | | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | | 登録日 | 2020-12-14 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex.
Sci Adv, 7, 2021
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6ZQP
 | | Structure of the Pmt2-MIR domain with bound ligands | | 分子名称: | GLYCEROL, PMT2 isoform 1, SULFATE ION, ... | | 著者 | Wild, K, Chiapparino, A, Hackmann, Y, Mortensen, S, Sinning, I. | | 登録日 | 2020-07-10 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Functional implications of MIR domains in protein O -mannosylation.
Elife, 9, 2020
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7B9S
 | | Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | | 分子名称: | EccB5, EccC5, EccD5, ... | | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | | 登録日 | 2020-12-14 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex.
Sci Adv, 7, 2021
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6TGY
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6TH3
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1L8G
 | | Crystal structure of PTP1B complexed with 7-(1,1-Dioxo-1H-benzo[d]isothiazol-3-yloxymethyl)-2-(oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid | | 分子名称: | 7-(1,1-DIOXO-1H-BENZO[D]ISOTHIAZOL-3-YLOXYMETHYL)-2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID, PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 | | 著者 | Iversen, L.F, Andersen, H.S, Moller, K.B, Olsen, O.H, Peters, G.H, Branner, S, Mortensen, S.B, Hansen, T.K, Lau, J, Ge, Y, Holsworth, D.D, Newman, M.J, Moller, N.P.H. | | 登録日 | 2002-03-20 | | 公開日 | 2002-05-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Steric hindrance as a basis for structure-based design of selective inhibitors of protein-tyrosine phosphatases.
Biochemistry, 40, 2001
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1C87
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 2-(OXALYL-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID | | 分子名称: | 2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID, PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B) | | 著者 | Iversen, L.F, Andersen, H.S, Mortensen, S.B, Moller, N.P. | | 登録日 | 2000-04-16 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B.
J.Biol.Chem., 275, 2000
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1C88
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID | | 分子名称: | 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B) | | 著者 | Iversen, L.F, Andersen, H.S, Mortensen, S.B, Moller, N.P. | | 登録日 | 2000-04-16 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B.
J.Biol.Chem., 275, 2000
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1KNU
 | | LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA IN COMPLEX WITH A SYNTHETIC AGONIST | | 分子名称: | (S)-3-(4-(2-CARBAZOL-9-YL-ETHOXY)-PHENYL)-2-ETHOXY-PROPIONIC ACID, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA | | 著者 | Svensson, L.A, Mortensen, S.B, Fleckner, J, Woeldike, H.F. | | 登録日 | 2001-12-19 | | 公開日 | 2002-12-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity
J.MED.CHEM., 45, 2002
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1C86
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B (R47V,D48N) COMPLEXED WITH 2-(OXALYL-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID | | 分子名称: | 2-(OXALYL-AMINO)-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBOXYLIC ACID, PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B) | | 著者 | Iversen, L.F, Andersen, H.S, Mortensen, S.B, Moller, N.P. | | 登録日 | 2000-04-16 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B.
J.Biol.Chem., 275, 2000
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