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5OTX

Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cys/Thr11Cys

Summary for 5OTX
Entry DOI10.2210/pdb5otx/pdb
DescriptorGlucagon-like peptide 1 receptor, Glucagon (3 entities in total)
Functional Keywordsglucagon-like peptide 1, gpcr, cyclic peptides, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight33883.39
Authors
Mortensen, S. (deposition date: 2017-08-22, release date: 2018-07-04, Last modification date: 2024-01-17)
Primary citationOddo, A.,Mortensen, S.,Thogersen, H.,De Maria, L.,Hennen, S.,McGuire, J.N.,Kofoed, J.,Linderoth, L.,Reedtz-Runge, S.
alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57:4148-4154, 2018
Cited by
PubMed: 29877701
DOI: 10.1021/acs.biochem.8b00105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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