2X43
 
 | | STRUCTURAL BASIS OF MOLECULAR RECOGNITION BY SHERP AT MEMBRANE SURFACES | | 分子名称: | SHERP | | 著者 | Moore, B, Miles, A.J, Guerra, C.G, Simpson, P, Iwata, M, Wallace, B.A, Matthews, S.J, Smith, D.F, Brown, K.A. | | 登録日 | 2010-02-09 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Moelcular Recognition by the Leishmania Small Hydrophilic Endoplasmic Reticulum-Associated Protein, Sherp, at Membrane Surfaces
J.Biol.Chem., 286, 2011
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3W8Z
 | | The complex structure of EncM with hydroxytetraketide | | 分子名称: | (7S)-7-hydroxy-1-phenyloctane-1,3,5-trione, FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM | | 著者 | Teufel, R, Miyanaga, A, Stull, F, Michaudel, Q, Louie, G, Noel, J.P, Baran, P.S, Palfey, B, Moore, B.S. | | 登録日 | 2013-03-22 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
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3W8X
 | | The complex structure of EncM with trifluorotriketide | | 分子名称: | 6,6,6-trifluoro-1-phenylhexane-1,3,5-trione, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Teufel, R, Miyanaga, A, Stull, F, Michaudel, Q, Louie, G, Noel, J.P, Baran, P.S, Palfey, B, Moore, B.S. | | 登録日 | 2013-03-22 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
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3W8W
 | | The crystal structure of EncM | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM | | 著者 | Teufel, R, Miyanaga, A, Stull, F, Michaudel, Q, Louie, G, Noel, J.P, Baran, P.S, Palfey, B, Moore, B.S. | | 登録日 | 2013-03-22 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
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8FFT
 | | Structure of GntC, a PLP-dependent enzyme catalyzing L-enduracididine biosynthesis from (S)-4-hydroxy-L-arginine | | 分子名称: | Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme, MAGNESIUM ION | | 著者 | Chen, P.Y.-T, Lima, S.T, Chekan, J.R, Moore, B.S. | | 登録日 | 2022-12-10 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mechanistic and Structural Insights into a Divergent PLP-Dependent l-Enduracididine Cyclase from a Toxic Cyanobacterium.
Acs Catalysis, 13, 2023
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8FFU
 | | Structure of GntC, a PLP-dependent enzyme catalyzing L-enduracididine biosynthesis from (S)-4-hydroxy-L-arginine, with the substrate bound | | 分子名称: | (2S,4S)-5-carbamimidamido-4-hydroxy-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]pentanoic acid (non-preferred name), Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme, MAGNESIUM ION | | 著者 | Chen, P.Y.-T, Moore, B.S. | | 登録日 | 2022-12-10 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Mechanistic and Structural Insights into a Divergent PLP-Dependent l-Enduracididine Cyclase from a Toxic Cyanobacterium.
Acs Catalysis, 13, 2023
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6OHJ
 | | Crystal Structure of the Debrominase Bmp8 C82A in Complex with 2,3,4-tribromopyrrole | | 分子名称: | 2,3,4-tribromo-1H-pyrrole, Debrominase Bmp8, SULFATE ION | | 著者 | Chekan, J.R, Moore, B.S. | | 登録日 | 2019-04-05 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Bacterial Tetrabromopyrrole Debrominase Shares a Reductive Dehalogenation Strategy with Human Thyroid Deiodinase.
Biochemistry, 58, 2019
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6OHI
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8CXL
 | | Structure of NapH3, a vanadium-dependent haloperoxidase homolog catalyzing the stereospecific alpha-hydroxyketone rearrangement reaction in napyradiomycin biosynthesis | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NapH3 | | 著者 | Chen, P.Y.-T, Chekan, J.R, Moore, B.S. | | 登録日 | 2022-05-21 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Biochemistry, 61, 2022
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6NSD
 | | Tar14, tryptophan C-6 flavin-dependent halogenase (chlorinase) from taromycin biosynthesis | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Tryptophan halogenase | | 著者 | Luhavaya, H, Chekan, J.R, Moore, B.S. | | 登録日 | 2019-01-24 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Biosynthesis of l-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide Antibiotics.
Angew.Chem.Int.Ed.Engl., 58, 2019
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7S2X
 | | Structure of SalC, a gamma-lactam-beta-lactone bicyclase for salinosporamide biosynthesis | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, POTASSIUM ION, SalC | | 著者 | Chen, P.Y.-T, Trivella, D.B.B, Bauman, K.D, Moore, B.S. | | 登録日 | 2021-09-04 | | 公開日 | 2022-04-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Enzymatic assembly of the salinosporamide gamma-lactam-beta-lactone anticancer warhead.
Nat.Chem.Biol., 18, 2022
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7S5L
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3W36
 | | Crystal structure of holo-type bacterial Vanadium-dependent chloroperoxidase | | 分子名称: | NapH1, VANADATE ION | | 著者 | Liscombe, D.K, Miyanaga, A, Fielding, E, Bernhardt, P, Li, A, Winter, J.M, Gilson, M.K, Noel, J.P, Moore, B.S. | | 登録日 | 2012-12-11 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Biochemistry, 2022
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3W35
 | | Crystal structure of apo-type bacterial Vanadium-dependent chloroperoxidase | | 分子名称: | NapH1 | | 著者 | Liscombe, D.K, Miyanaga, A, Fielding, E, Bernhardt, P, Li, A, Winter, J.M, Gilson, M.K, Noel, J.P, Moore, B.S. | | 登録日 | 2012-12-11 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Biochemistry, 2022
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6VL0
 | | Crystal Structure of the N-prenyltransferase DabA in Complex with GSPP and Mn2+ | | 分子名称: | DabA, GERANYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Chekan, J.R, Noel, J.P, Moore, B.S. | | 登録日 | 2020-01-22 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase.
Proc.Natl.Acad.Sci.USA, 117, 2020
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2H84
 | | Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium) | | 分子名称: | HEXAETHYLENE GLYCOL, Steely1 | | 著者 | Austin, M.B, Saito, T, Bowman, M.E, Haydock, S, Kato, A, Moore, B.S, Kay, R.R, Noel, J.P. | | 登録日 | 2006-06-06 | | 公開日 | 2006-08-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.
Nat.Chem.Biol., 2, 2006
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6VL1
 | | Crystal Structure of the N-prenyltransferase DabA in Complex with NGG and Mg2+ | | 分子名称: | DabA, MAGNESIUM ION, N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-L-glutamic acid | | 著者 | Chekan, J.R, Noel, J.P, Moore, B.S. | | 登録日 | 2020-01-22 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VKZ
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5BUL
 | | Structure of flavin-dependent brominase Bmp2 triple mutant Y302S F306V A345W | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, flavin-dependent halogenase triple mutant | | 著者 | Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S. | | 登録日 | 2015-06-04 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9784 Å) | | 主引用文献 | Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5BVA
 | | Structure of flavin-dependent brominase Bmp2 | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, flavin-dependent halogenase | | 著者 | Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S. | | 登録日 | 2015-06-04 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.873 Å) | | 主引用文献 | Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5BUK
 | | Structure of flavin-dependent chlorinase Mpy16 | | 分子名称: | FADH2-dependent halogenase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | | 著者 | Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S. | | 登録日 | 2015-06-03 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2O7E
 | | Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant), bound to 2-aminoindan-2-phosphonic acid | | 分子名称: | (2-AMINO-2,3-DIHYDRO-1H-INDEN-2-YL)PHOSPHONIC ACID, Putative histidine ammonia-lyase | | 著者 | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | | 登録日 | 2006-12-11 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
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2NYF
 | | Crystal structure of phenylalanine ammonia-lyase from Nostoc punctiforme | | 分子名称: | Nostoc punctiforme phenylalanine ammonia lyase | | 著者 | Louie, G.V, Moffitt, M.C, Bowman, M.E, Pence, J, Noel, J.P, Moore, B.S. | | 登録日 | 2006-11-20 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
Biochemistry, 46, 2007
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2O78
 | | Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant) complexed with cinnamic acid | | 分子名称: | PHENYLETHYLENECARBOXYLIC ACID, Putative histidine ammonia-lyase | | 著者 | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | | 登録日 | 2006-12-10 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
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2O6Y
 | | Tyrosine ammonia-lyase from Rhodobacter sphaeroides | | 分子名称: | Putative histidine ammonia-lyase | | 著者 | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | | 登録日 | 2006-12-09 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
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