7T6M
| Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1 | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
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7T6L
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7T6Q
| Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
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7T6P
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7T6O
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7T6N
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8EKR
| Apo rat TRPV2 in nanodiscs, state 3 | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 | 著者 | Pumroy, R.A, Moiseenkova-Bell, V.Y. | 登録日 | 2022-09-21 | 公開日 | 2023-09-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
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8EKS
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8EKP
| Apo rat TRPV2 in nanodiscs, state 1 | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 | 著者 | Pumroy, R.A, Moiseenkova-Bell, V.Y. | 登録日 | 2022-09-21 | 公開日 | 2023-09-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
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8EKQ
| Apo rat TRPV2 in nanodiscs, state 2 | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 | 著者 | Pumroy, R.A, Moiseenkova-Bell, V.Y. | 登録日 | 2022-09-21 | 公開日 | 2023-09-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Functional and structural insights into activation of TRPV2 by weak acids. Embo J., 43, 2024
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8FHI
| Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), ... | 著者 | De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y. | 登録日 | 2022-12-14 | 公開日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nat Commun, 14, 2023
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8FFO
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8FHH
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8FFQ
| Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ... | 著者 | De Jesus-Perez, J.J, Fluck, E.C, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y. | 登録日 | 2022-12-09 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25, 2024
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8FFM
| Wildtype rat TRPV2 in nanodiscs bound to RR and 2-APB | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, ... | 著者 | Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y. | 登録日 | 2022-12-09 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25, 2024
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8FFL
| Wildtype rat TRPV2 in nanodiscs bound to RR | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2 | 著者 | Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y. | 登録日 | 2022-12-09 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25, 2024
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8FFN
| RR-bound wildtype rabbit TRPV5 in nanodiscs | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ... | 著者 | Fluck, E.C, De Jesus-Perez, J.J, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y. | 登録日 | 2022-12-09 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25, 2024
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