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PDB: 42 件

7T6M
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BU of 7t6m by Molmil
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6L
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BU of 7t6l by Molmil
Cryo-EM structure of TRPV5 at pH5 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6Q
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BU of 7t6q by Molmil
Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6P
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BU of 7t6p by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6O
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BU of 7t6o by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6N
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BU of 7t6n by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
8EKR
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BU of 8ekr by Molmil
Apo rat TRPV2 in nanodiscs, state 3
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2022-09-21
公開日2023-09-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Functional and structural insights into activation of TRPV2 by weak acids.
Embo J., 43, 2024
8EKS
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BU of 8eks by Molmil
rat TRPV2 in nanodiscs in the presence of weak acid at pH 5
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2022-09-21
公開日2023-09-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Functional and structural insights into activation of TRPV2 by weak acids.
Embo J., 43, 2024
8EKP
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BU of 8ekp by Molmil
Apo rat TRPV2 in nanodiscs, state 1
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2022-09-21
公開日2023-09-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Functional and structural insights into activation of TRPV2 by weak acids.
Embo J., 43, 2024
8EKQ
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BU of 8ekq by Molmil
Apo rat TRPV2 in nanodiscs, state 2
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2022-09-21
公開日2023-09-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Functional and structural insights into activation of TRPV2 by weak acids.
Embo J., 43, 2024
8FHI
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BU of 8fhi by Molmil
Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), ...
著者De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y.
登録日2022-12-14
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
8FFO
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BU of 8ffo by Molmil
Cryo-EM structure of wildtype rabbit TRPV5 with PI(4,5)P2 in nanodiscs
分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
著者De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
8FHH
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BU of 8fhh by Molmil
Wildtype rabbit TRPV5 in nanodiscs in the presence of oleoyl coenzyme A, Closed stated
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5
著者De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y.
登録日2022-12-14
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
8FFQ
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BU of 8ffq by Molmil
Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red
分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
著者De Jesus-Perez, J.J, Fluck, E.C, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFM
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BU of 8ffm by Molmil
Wildtype rat TRPV2 in nanodiscs bound to RR and 2-APB
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, ...
著者Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFL
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BU of 8ffl by Molmil
Wildtype rat TRPV2 in nanodiscs bound to RR
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFN
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BU of 8ffn by Molmil
RR-bound wildtype rabbit TRPV5 in nanodiscs
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
著者Fluck, E.C, De Jesus-Perez, J.J, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
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件を2024-11-06に公開中

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